URL: https://web.expasy.org/cellosaurus/CVCL_0426
Proper Citation: (RRID:CVCL_0426)
Description: Cell line MG-63 is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Male
Disease: Osteosarcoma
Defining Citation: PMID:218153, PMID:883813, PMID:1577731, PMID:2233717, PMID:2823272, PMID:7873286, PMID:8617485, PMID:9144345, PMID:9600771, PMID:12645653, PMID:15736406, PMID:17981215, PMID:19160414, PMID:19363654, PMID:19787792, PMID:20164919, PMID:20215515, PMID:21519327, PMID:22460905, PMID:23129384, PMID:23144859, PMID:24903274, PMID:25382592, PMID:25485619, PMID:25877200, PMID:26320182, PMID:26589293, PMID:27397505, PMID:28196595, PMID:29334376, PMID:30894373, PMID:31068700, PMID:35839778, PMID:36480329
Comments: Caution: The reported STR profile from CLS of this cell line was changed in June 2019. Seven conflicts with other sources were resolved.., Anecdotal: Have been flown in space on Foton-10 and Foton-M3 to study if differentiation is altered in microgravity (PubMed=9144345; PubMed=9600771; PubMed=24903274)., Omics: Transcriptome analysis by RNAseq., Omics: Transcriptome analysis by microarray., Omics: SNP array analysis., Omics: Protein expression by reverse-phase protein arrays., Omics: Metabolome analysis., Omics: H3K27ac ChIP-seq epigenome analysis., Omics: H3K4me1 ChIP-seq epigenome analysis., Omics: DNA methylation analysis., Omics: Deep quantitative proteome analysis., Omics: Deep exome analysis., Omics: CNV analysis., Omics: Array-based CGH., Characteristics: Can be induced to differentiate by treating the cells with 1,25-dihydroxyvitamin D3 and TGF-beta. The cells do not differentiate into the mineralized state, but stop at the matrix maturation stage (PubMed=1577731)., Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Category: Cancer cell line
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Source: Cellosaurus
