URL: https://web.expasy.org/cellosaurus/CVCL_D585
Proper Citation: (RRID:CVCL_D585)
Description:
Sex: Female
Comments: Biotechnology: Used for the production of the AstraZeneca SARS-CoV-2 (COVID-19) vaccine (Trade name: Vaxzevria; also known as ChAdOx1-SARS-COV-2 or AZD1222) (DrugBank=DB15656). In the context of the vaccine production, the tetR repressor blocks the expression of the SARS-CoV-2 spike protein gene during production of the recombinant adenoviral vector, thereby optimising vector production., Part of: ENCODE project common cell types; tier 3., Group: Vaccine production cell line.
Category: Transformed cell line
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Source: Cellosaurus
