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Proper Citation: RRID:MGI:5292226
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal roof plate morphology, neonatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, postnatal growth retardation, cellular phenotype, abnormal renal tubule epithelial cell primary cilium morphology, kidney cysts, postnatal lethality, abnormal embryonic neuroepithelium morphology, abnormal dorsal-ventral axis patterning, abnormal corpus callosum morphology, abnormal cell morphology, abnormal forebrain development, incomplete rostral neuropore closure, increased forebrain size, kidney cysts, limbs/digits/tail phenotype, mandible hypoplasia, meningomyelocele, abnormal hepatobiliary system development, microcephaly, perinatal lethality, abnormal brain ependyma motile cilium morphology, abnormal basal ganglion morphology, abnormal posterior cranial fossa morphology, abnormal midbrain development, abnormal nervous system morphology, abnormal neural fold morphology, abnormal neural tube morphology, abnormal neural tube ventricular layer morphology, abnormal tegmentum morphology, decreased hindbrain size, absent anterior commissure, absent embryonic cilia, cerebellum vermis hypoplasia, decreased forebrain size, dilated fourth ventricle, small cerebellum, encephalomeningocele, enlarged hippocampus, exencephaly, holoprosencephaly
Affected Gene: Tmem67
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI