CHEBI:138179 - aspirin-triggered resolvin D1

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name aspirin-triggered resolvin D1
ChEBI ID CHEBI:138179
Definition A member of the class of resolvins that consists of docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid carrying three hydroxy substituents at positions 7, 8, and 17 (the 7S,8R,17S-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C22H32O5
Net Charge 0
Average Mass 376.487
Monoisotopic Mass 376.22497
InChI InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21+/m1/s1
InChIKey OIWTWACQMDFHJG-BJEBZIPWSA-N
SMILES C(CC/C=C\C[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@@H](C/C=C\CC)O)O)O)(O)=O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antiviral agent
A substance that destroys or inhibits replication of viruses.
analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
TGFbeta receptor antagonist
An antagonist that binds to and deactivates TGFbeta receptors.
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
nephroprotective agent
Any protective agent that is able to prevent damage to the kidney.
anti-allergic agent
A drug used to treat allergic reactions.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing aspirin-triggered resolvin D1 (CHEBI:138179) has role analgesic (CHEBI:35480)
aspirin-triggered resolvin D1 (CHEBI:138179) has role anti-allergic agent (CHEBI:50857)
aspirin-triggered resolvin D1 (CHEBI:138179) has role anti-inflammatory agent (CHEBI:67079)
aspirin-triggered resolvin D1 (CHEBI:138179) has role antiviral agent (CHEBI:22587)
aspirin-triggered resolvin D1 (CHEBI:138179) has role human xenobiotic metabolite (CHEBI:76967)
aspirin-triggered resolvin D1 (CHEBI:138179) has role nephroprotective agent (CHEBI:76595)
aspirin-triggered resolvin D1 (CHEBI:138179) has role TGFβ receptor antagonist (CHEBI:91202)
aspirin-triggered resolvin D1 (CHEBI:138179) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
aspirin-triggered resolvin D1 (CHEBI:138179) is a resolvin (CHEBI:132120)
aspirin-triggered resolvin D1 (CHEBI:138179) is a secondary allylic alcohol (CHEBI:134396)
IUPAC Name
(4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
Synonyms Sources
(4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosahexaenoic acid ChEBI
17(R)-resolvin D1 ChEBI
17(R)-RvD1 ChEBI
17-epi-resolvin D1 ChEBI
7S,8R,17R-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid LIPID MAPS
AT-Resolvin D1 LIPID MAPS
AT-RvD1 LIPID MAPS
Manual Xref Database
LMFA04030005 LIPID MAPS
View more database links
Registry Number Type Source
24477830 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
17244615 PubMed citation Europe PMC
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Last Modified
05 March 2018