CHEBI:40823 - (aminooxy)acetic acid

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ChEBI Name (aminooxy)acetic acid
ChEBI ID CHEBI:40823
Definition A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of γ-aminobutyric acid in tissues.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C2H5NO3
Net Charge 0
Average Mass 91.066
Monoisotopic Mass 91.02694
InChI InChI=1S/C2H5NO3/c3-6-1-2(4)5/h1,3H2,(H,4,5)
InChIKey NQRKYASMKDDGHT-UHFFFAOYSA-N
SMILES NOCC(O)=O
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): EC 4.2.1.22 (cystathionine beta-synthase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine beta-synthase (EC 4.2.1.22).
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate2-oxoglutarate transaminase (EC 2.6.1.19).
Application(s): nootropic agent
Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
anticonvulsant
A drug used to prevent seizures or reduce their severity.
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ChEBI Ontology
Outgoing (aminooxy)acetic acid (CHEBI:40823) has role anticonvulsant (CHEBI:35623)
(aminooxy)acetic acid (CHEBI:40823) has role EC 2.6.1.19 (4-aminobutyrate—2-oxoglutarate transaminase) inhibitor (CHEBI:63674)
(aminooxy)acetic acid (CHEBI:40823) has role EC 4.2.1.22 (cystathionine β-synthase) inhibitor (CHEBI:63157)
(aminooxy)acetic acid (CHEBI:40823) has role nootropic agent (CHEBI:66980)
(aminooxy)acetic acid (CHEBI:40823) is a amino acid (CHEBI:33709)
(aminooxy)acetic acid (CHEBI:40823) is a hydroxylamines (CHEBI:24709)
(aminooxy)acetic acid (CHEBI:40823) is a monocarboxylic acid (CHEBI:25384)
(aminooxy)acetic acid (CHEBI:40823) is conjugate acid of (aminooxy)acetate (CHEBI:157642)
Incoming (aminooxy)acetate (CHEBI:157642) is conjugate base of (aminooxy)acetic acid (CHEBI:40823)
IUPAC Name
(aminooxy)acetic acid
Synonyms Sources
(carboxymethoxy)amine ChemIDplus
(O-carboxymethyl)hydroxylamine ChemIDplus
2-(aminooxy)acetic acid IUPAC
2-aminooxyethanoic acid PDBeChem
aminooxyacetic acid ChemIDplus
AOA
Note: (2020-10-15) Used as an abbreviation.
 ChEBI
AOAA
Note: (2020-10-15) Used as an abbreviation.
 ChemIDplus
carboxymethoxyamine DrugBank
U-7524 DrugBank
Manual Xrefs Databases
280 ChemSpider
Aminooxyacetic_acid Wikipedia
AOA PDBeChem
CARBOXYMETHOXYLAMINE MetaCyc
DB02079 DrugBank
View more database links
Registry Numbers Types Sources
645-88-5 CAS Registry Number ChemIDplus
878238 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
15 October 2020