CHEBI:60815 - lysobisphosphatidic acid

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ChEBI Name lysobisphosphatidic acid ChEBI ID CHEBI:60815 Definition A lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group. Stars This entity has been manually annotated by the ChEBI Team. Roles Classification Biological Role(s): mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). (via monoacylglycerol phosphate ) View more via ChEBI Ontology ChEBI Ontology Outgoing lysobisphosphatidic acid (CHEBI:60815) has functional parent glycerophosphoglycerol (CHEBI:5457) lysobisphosphatidic acid (CHEBI:60815) is a lysophosphatidic acids (CHEBI:32957) Incoming (R,R)-bis(2-oleoylglycero)-3-phosphate (CHEBI:139583) is a lysobisphosphatidic acid (CHEBI:60815) 1,1'-lysobisphosphatidic acid (CHEBI:60817) is a lysobisphosphatidic acid (CHEBI:60815) 2,2'-lysobisphosphatidic acid (CHEBI:60818) is a lysobisphosphatidic acid (CHEBI:60815) Synonyms Sources bis(monoacylglycerol) hydrogen phosphate ChEBI BMP ChEBI LBPA ChEBI Citations Types Sources 10101262 PubMed citation Europe PMC 12008959 PubMed citation Europe PMC 18052935 PubMed citation Europe PMC 19857945 PubMed citation Europe PMC Last Modified 05 February 2018

General Comments 2010-12-17 Although either R1 or R2 of the diagram may equally be a fatty acyl or a hydrogen moiety, evidence to date indicates that the fatty acids are esterified to positions sn-2 and sn-2' in the native molecule. (http://lipidlibrary.aocs.org/lipids/lysobpa/index.htm). 2010-12-17 LBPA is involved in cholesterol homoeostasis, in the pathology of lysosomal storage diseases and in the development of antiphospholipid syndrome.