KEGG ENZYME: 5.3.99.9

ENZYME: 5.3.99.9

Entry

EC 5.3.99.9                 Enzyme

Name

neoxanthin synthase;
NSY

Class

Isomerases;
Intramolecular oxidoreductases;
Other intramolecular oxidoreductases

Sysname

violaxanthin---neoxanthin isomerase (epoxide-opening)

Reaction(IUBMB)

violaxanthin = neoxanthin [RN:R06948]

Reaction(KEGG)

R06948;
(other) R06951

Substrate

violaxanthin [CPD:C08614]

Product

neoxanthin [CPD:C08606]

Comment

The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].

History

EC 5.3.99.9 created 2005

Pathway

ec00906

Carotenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K14594

neoxanthin synthase

Genes

SLY:	543649(NSY)

SPEN:

107023247

SOT:	102601215(nxs)

SSTN:

125872065

SDUL:

129899626

LBB:

132604100

ITR:

116017470

Reference

1 [PMID:11094161]

Authors

Al-Babili S, Hugueney P, Schledz M, Welsch R, Frohnmeyer H, Laule O, Beyer P

Title

Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum.

Journal

FEBS Lett 485:168-72 (2000)
DOI:10.1016/S0014-5793(00)02193-1

Sequence

[sot:102601215]

Reference

2 [PMID:11029576]

Authors

Bouvier F, D'harlingue A, Backhaus RA, Kumagai MH, Camara B

Title

Identification of neoxanthin synthase as a carotenoid cyclase paralog.

Journal

Eur J Biochem 267:6346-52 (2000)
DOI:10.1046/j.1432-1327.2000.01722.x

Sequence

[sly:543649]

Other DBs

ExplorEnz - The Enzyme Database:

5.3.99.9

IUBMB Enzyme Nomenclature:

5.3.99.9

ExPASy - ENZYME nomenclature database:

5.3.99.9

BRENDA, the Enzyme Database:

5.3.99.9

CAS:	318960-21-3

DBGET integrated database retrieval system