Project: PRJEB33938
The human brain has changed dramatically since humans diverged from our closest living relatives, chimpanzees and the other great apes. However, the genetic and developmental programs underlying this divergence are not fully understood. Here, we generate single-nucleus RNA-seq data of human, chimpanzee and macaque adult prefrontal cortex. Spatial information is obtained by isolating nuclei from sequential sections sliced from basal to apical positions. Bulk RNA-seq is performed for the same sections to determine positional information of the sections, by comparing the section transcriptome with published transcriptome data of cortical layers in human, chimpanzee and macaque.
Secondary Study Accession:
ERP116771
Study Title:
RNA-seq of prefrontal cortex in adult human, chimp and macaque
Center Name:
European Bioinformatics Institute;Department of Biosystems Science and Engineering;ETH Zurich
Study Name:
RNA-seq of prefrontal cortex in adult human, chimp and macaque
Broker Name:
ArrayExpress
ENA-FIRST-PUBLIC:
2019-10-04
ENA-LAST-UPDATE:
2019-08-08
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