Project: PRJNA667173
Here, we studied transcriptome profiles of human nail units from polydactly samples. Single cell RNAseq with 11,541 cells from 4 extra digits revealed nail-specific mesenchymal and epithelial cell populations Overall design: We profiled transcriptomes of nail unit from 4 fresh human polydactyly specimens using single cell RNAseq (scRNAseq). Extra-digits from 6-12 months old patients were delivered to the dermatologic clinic immediately after the digit removal. All samples containing nail mesenchyme and epithelium were minced and dissociated within 3 hours of digit removal.
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