Examples: histone, BN000065

Project: PRJNA903479

To examine whether commonly used human cultured fibroblast systems model human cardiac fibroblasts, we tested three different fibroblast cell preparations: primary human cardiac fibroblasts (NHCF), human dermal fibroblasts (NHDF), and immortalized human cardiac fibroblasts (iHCF). Overall design: Each fibroblast cell line was treated with vehicle, TGF-β, or IL-1β for 72 hours and scRNAseq performed. Multiple biological and technical replicates were included, individually hash tagged, and pooled to minimize any potential batch effects.

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