Description
Transcriptional activator of the pleiotropic drug resistance network; regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting PDRE sites (PDR responsive elements); has a role in response to drugs and organic solvents; post-translationally up-regulated in cells lacking functional mitochondrial genome; involved in diauxic shift; relative distribution to nucleus increases upon DNA replication stress; APCC(Cdh1) substrate [Source:SGD;Acc:S000000101]
Gene Synonyms
AMY2, TPE2
Location
Chromosome II: 217,470-220,400 forward strand.
R64-1-1:BK006936.2
About this gene
This gene has 1 transcript (splice variant) and 2 paralogues.
Transcripts
