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| Status |
Public on Sep 27, 2018 |
| Title |
Composition of the Colonic Mesenchyme and the Nature of its Plasticity in Inflammatory Bowel Disease |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
10x Chromium single cell RNA-Seq of colonic mesenchyme cell populations in health and Ulcerative Colitis in human patients and health in DSS-induced colitis in murine colon
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| Overall design |
Cells from colon of three healthy mice and 3 DSS-treated mice were sequenced on 10x Chromium /hiSeq4000 instruments. Cells from 2 healthy and 2 UC human patients were isolated and sequenced using 10x Chromium /hiSeq4000 instruments.
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| Contributor(s) |
Kinchen J, Chen H, Parikh K, Antanaviciute A, Jagielowicz M, Fawkner-Corbett D, Ashley N, Mellado-Gomez E, Attar M, Sharma E, Wills Q, Bowden R, Richter F, Ahern D, Henault J, Gervais F, Puri K, Koohy H, Simmons A |
| Citation(s) |
30270042 |
| Submission date |
May 13, 2018 |
| Last update date |
Apr 23, 2020 |
| Contact name |
Alison Simmons |
| E-mail(s) |
alison.simmons@ndm.ox.ac.uk
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| Organization name |
University of Oxford
|
| Department |
The MRC Weatherall Institute of Molecular Medicine
|
| Street address |
John Radcliffe Hospital/Headley Way
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| City |
Oxford |
| ZIP/Postal code |
OX3 9DS |
| Country |
United Kingdom |
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| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA471188 |
| SRA |
SRP145547 |
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