|
| Status |
Public on May 01, 2019 |
| Title |
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinically diagnosed with Rett syndrome and four age-matched female donors. The dataset contains transcriptomes from two brain regions, temporal and cingulate cortex, for each individual, providing a valuable resource to explore the biology of the human brain in Rett syndrome.
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| |
|
| Overall design |
Transcriptional profiles for postmortem temporal and cingulate cortex from four females with Rett syndrome and four age-matched controls.
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| |
|
| Contributor(s) |
Aldinger KA |
| Citation(s) |
32561870 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 MH067842 |
Function and Structure Adaptations in Forebrain Development |
CHILDREN'S HOSPITAL LOS ANGELES |
PAT LEVITT |
|
| Submission date |
Mar 15, 2019 |
| Last update date |
Jun 29, 2020 |
| Contact name |
Kimberly A Aldinger |
| E-mail(s) |
kimberly.aldinger@seattlechildrens.org
|
| Organization name |
Seattle Children's Research Institute
|
| Street address |
1900 Nineth Ave
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98101 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA527289 |
| SRA |
SRP188555 |
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