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| Status |
Public on Sep 21, 2019 |
| Title |
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Here we perform massively parallel single-cell RNA sequencing (scRNA-seq) of human retinas using two independent platforms, and report the single-cell transcriptomic atlas of the human retina. Using a multi-resolution network-based analysis, we identify all major retinal cell types, and their corresponding gene expression signatures.
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| |
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| Overall design |
Three replicates of macula and peripheral retinas.
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| |
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| Contributor(s) |
Menon M, Mohammadi S, Davila-Velderrain J, Goods BA, Cadwell TD, Xing Y, Rachamimov AS, Shalek AK, Love JC, Kellis K, Hafler BP |
| Citation(s) |
31653841 |
| Submission date |
Sep 16, 2019 |
| Last update date |
Nov 04, 2019 |
| Contact name |
Brian Hafler |
| E-mail(s) |
brian.hafler@yale.edu
|
| Organization name |
Yale School of Medicine
|
| Street address |
300 George Street
|
| City |
New Haven |
| State/province |
Connecticut |
| ZIP/Postal code |
06511 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE137847 |
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration |
|
| Relations |
| BioProject |
PRJNA565928 |
| SRA |
SRP222001 |
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