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Series GSE153419 Query DataSets for GSE153419
Status Public on Jun 29, 2020
Title Transcriptomic response of SIM-A9 microglia to neuro-probes
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary This study aims to elucidate the response of microglial cells to various molecular probes used in neuroscience for the detection of neurotransmission. Particularly, we aim to quantify the degree of inflammatory activation observed in these cells upon exposure to carbon nanotube catecholamine sensors. We compare these results to carboxylic acid functionalized carbon nanotubes which have previously been implicated in macrophage activation, and lipopolysaccharide as a positive control.
 
Overall design Study of effects of neuro-probes, including novel carbon nanotube based platforms, on SIM-A9 mouse microglial cells. Inflammatory response compared to LPS positive control
 
Contributor(s) Yang D, Landry MP
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jun 28, 2020
Last update date Jun 30, 2020
Contact name Markita Landry
E-mail(s) landry@berkeley.edu
Organization name University of California, Berkeley
Department Chemical Engineering
Street address 106 Gilman Hall
City Berkeley
State/province CA
ZIP/Postal code 94720-1762
Country USA
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (24)
GSM4643981 SIM-A9_AAV_2h_rep1
GSM4643982 SIM-A9_AAV_2h_rep2
GSM4643983 SIM-A9_AAV_2h_rep3
Relations
BioProject PRJNA642407
SRA SRP269075

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE153419_190917_DY_RNA-seq_rawcounts.txt.gz 998.8 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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