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Status |
Public on Jun 29, 2020 |
Title |
Transcriptomic response of SIM-A9 microglia to neuro-probes |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
This study aims to elucidate the response of microglial cells to various molecular probes used in neuroscience for the detection of neurotransmission. Particularly, we aim to quantify the degree of inflammatory activation observed in these cells upon exposure to carbon nanotube catecholamine sensors. We compare these results to carboxylic acid functionalized carbon nanotubes which have previously been implicated in macrophage activation, and lipopolysaccharide as a positive control.
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Overall design |
Study of effects of neuro-probes, including novel carbon nanotube based platforms, on SIM-A9 mouse microglial cells. Inflammatory response compared to LPS positive control
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Contributor(s) |
Yang D, Landry MP |
Citation missing |
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Submission date |
Jun 28, 2020 |
Last update date |
Jun 30, 2020 |
Contact name |
Markita Landry |
E-mail(s) |
landry@berkeley.edu
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Organization name |
University of California, Berkeley
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Department |
Chemical Engineering
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Street address |
106 Gilman Hall
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City |
Berkeley |
State/province |
CA |
ZIP/Postal code |
94720-1762 |
Country |
USA |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (24)
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Relations |
BioProject |
PRJNA642407 |
SRA |
SRP269075 |