|
| Status |
Public on Oct 26, 2020 |
| Title |
FOXA1-dependent responses of the HER2+ SKBR-3 cell line to lapatinib |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
SKBR-3 HER2+ breast cancer cells were treated with 25 nM Dharmacon siGENOME non-targeting (NT) siRNA control pool or siRNA pool targeting FOXA1 for 48h, then treated with either DMSO or 300nM lapatinib for 24h.
|
| |
|
| Overall design |
12 experimental samples
|
| |
|
| Contributor(s) |
Johnson GL, Angus SP |
| Citation(s) |
33980863 |
| Submission date |
Oct 23, 2020 |
| Last update date |
May 10, 2023 |
| Contact name |
Steven P Angus |
| E-mail(s) |
sangus@iu.edu
|
| Phone |
317-274-8911
|
| Organization name |
Indiana University School of Medicine
|
| Department |
Pediatrics
|
| Street address |
1044 W Walnut St
|
| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46202 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (12)
|
|
| This SubSeries is part of SuperSeries: |
| GSE160670 |
Adaptive responses to HER2-directed therapy in breast cancer cell line models |
|
| Relations |
| BioProject |
PRJNA671641 |
| SRA |
SRP288463 |
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