|
| Status |
Public on Jan 01, 2022 |
| Title |
Human Obstructive and Non-obstructive Hypertrophic Cardiomyopathy Disease Mechanisms |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To understand the interplay between cardiomyocyte and nonmyocyte cell types in human obstructive and non-obstructive hypertrophic cardiomyopathy, single nuclei RNA-sequencing was performed on 2 unused donor hearts, 1 obstructive HCM specimen, and 6 non-obstructive HCM specimens.
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| |
|
| Overall design |
Specimens were sampled for single nuclei transcriptomic sequencing. Sample 16 was generated and sequenced on its own NovaSeq S4 run. Samples 14-15 and 17-22 were generated and sequenced togheter on a separate NovaSeq S4 run.
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| |
|
| Contributor(s) |
Codden CJ, Chin MT |
| Citation(s) |
35055131, 36237479, 37628806 |
| Submission date |
Aug 10, 2021 |
| Last update date |
Feb 21, 2024 |
| Contact name |
Gayani Perera |
| Organization name |
Tufts Medical Center
|
| Department |
MCRI
|
| Lab |
Chin Lab
|
| Street address |
800 Washington Street
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02111 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL21697 |
NextSeq 550 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA753316 |
| SRA |
SRP331843 |
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