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Status |
Public on Jul 10, 2014 |
Title |
DNA Methylation Analysis of Systemic Lupus Erythematosus |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by array
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Summary |
This study performed Illumina Methylation450 analysis of CD4+ T-cells, CD19+ B-cells and CD14+ Monocytes from lupus patients and controls. A validation cohort was further analyzed with the same platform using CD4+ T-cells, CD45RO-CD45RA+ naive T-cells, CD45RO+CD45RA- memory T-cells, and CD25+CD127- regulatory T-cells.
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Overall design |
SLE v Control comparisions were made within each cell type. The SLE patient samples are labeled SLEnnnn and the controls Xnnnn. The cell type CD4, CD14, CD19, Tmem, Treg, Tnaive is appended to each sample ID.
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Citation(s) |
23950730 |
Submission date |
Jul 09, 2014 |
Last update date |
Mar 22, 2019 |
Contact name |
Devin Absher |
E-mail(s) |
dabsher@hudsonalpha.org
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Organization name |
HudsonAlpha Institute for Biotechnology
|
Street address |
601 Genome Way
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City |
Huntsville |
State/province |
AL |
ZIP/Postal code |
35806 |
Country |
USA |
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Platforms (1) |
GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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Samples (434)
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Relations |
BioProject |
PRJNA254821 |