| Entry |
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| Symbol |
Egfr
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| Name |
(RefSeq) epidermal growth factor receptor, isoform B
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| KO |
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| Organism |
dme Drosophila melanogaster (fruit fly)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:dme00001]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
Dmel_CG10079 (Egfr)
09130 Environmental Information Processing
09132 Signal transduction
04013 MAPK signaling pathway - fly
Dmel_CG10079 (Egfr)
04068 FoxO signaling pathway
Dmel_CG10079 (Egfr)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
Dmel_CG10079 (Egfr)
09143 Cell growth and death
04214 Apoptosis - fly
Dmel_CG10079 (Egfr)
09150 Organismal Systems
09158 Development and regeneration
04320 Dorso-ventral axis formation
Dmel_CG10079 (Egfr)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:dme01001]
Dmel_CG10079 (Egfr)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:dme04147]
Dmel_CG10079 (Egfr)
Enzymes [BR:dme01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
Dmel_CG10079 (Egfr)
Protein kinases [BR:dme01001]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
Dmel_CG10079 (Egfr)
Exosome [BR:dme04147]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
Dmel_CG10079 (Egfr)
Exosomal proteins of pancreatic cancer cells
Dmel_CG10079 (Egfr)
Exosomal proteins of bladder cancer cells
Dmel_CG10079 (Egfr)
Cytokine receptors [BR:dme04050]
Receptor tyrosine kinase
RTK class I (EGF receptor family)
Dmel_CG10079 (Egfr)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
2R
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| AA seq |
1426 aa
MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRS
SSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYR
NLRDRYTNCTYVDGNLELTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIR
GRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVS
NGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPR
ECCHLFCAGGCTGPTQKDCIACKNFFDEGVCKEECPPMRKYNPTTYVLETNPEGKYAYGA
TCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNC
TVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERLEVFSTVKEITGYLNIEGTHPQF
RNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVS
NIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNG
TCIADCGYISNAYKFDNRTCKICHPECRTCNGAGADHCQECVHVRDGQHCVSECPKNKYN
DRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYV
HPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTD
EEQRECFQCHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHV
NYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKK
ETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPE
GENVKIPVAIKELLKSTGAESSEEFLREAYIMASVEHVNLLKLLAVCMSSQMMLITQLMP
LGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKIT
DFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRP
HENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARD
PGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAEPDDYLQPKAAPGPSHRTD
CTDEIPKLNRYCKDPSNKNSSTGDDETDSSAREVGVGNLRLDLPVDEDDYLMPTCQPGPN
NNNNINNPNQNNMAAVGVAAGYMDLIGVPVSVDNPEYLLNAQTLGVGESPIPTQTIGIPV
MGVPGTMEVKVPMPGSEPTSSDHEYYNDTQRELQPLHRNRNTETRV |
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| NT seq |
4281 nt +upstreamnt +downstreamnt
atgctgctgcgacggcgcaacggcccctgccccttccccctgctgctcctgctcctggcc
cactgcatttgcatttggcccgcgtcggcggcccgcgatcgctacgcccgccagaacaat
cgccagcgccatcaggatatagatcgcgatcgggatcgagatcgattcctataccgcagc
agttcggcccaaaatcgacagaggggcggggccaacttcgccctgggactgggagccaac
ggagtcaccattcccaccagtctggaggataagaacaagaacgagttcgtcaaggggaaa
atctgcatcggcactaaatctcggctctccgtgccctccaacaaggaacatcattaccgg
aacctcagagatcggtacacgaactgtacgtatgtggatggcaacctggagctgacctgg
ctgcccaacgagaatttggacctcagcttcctggacaacatacgggaggtcaccggctat
attctgatcagtcatgtggacgttaagaaagtggtatttcccaaactacaaatcattcgc
ggacgcacgctgttcagcttatccgtggaggaggagaagtatgccttgttcgtcacttat
tccaaaatgtacacgctggagattcccgatctacgcgatgtcttaaatggccaagtgggc
ttccacaacaactacaatctctgccacatgcgaacgatccagtggtcggagattgtatcc
aacggcacggatgcatactacaactacgactttactgctccggagcgcgagtgtcccaag
tgccacgagagctgcacgcacggatgttggggcgagggtcccaagaattgccagaagttc
agcaagctcacctgctcgccacagtgtgccggaggtcgttgctatggaccaaagccgcgg
gagtgttgtcacctcttctgcgccggaggatgcactggtcccacgcaaaaggattgcatc
gcctgcaagaacttcttcgacgagggcgtatgcaaggaggaatgcccgcccatgcgcaag
tacaatcccaccacctatgttcttgaaacgaatcctgagggaaagtatgcctatggtgcc
acctgcgtcaaggagtgtcccggtcatctgttgcgtgataatggcgcctgcgtgcgcagc
tgtccccaggacaagatggacaaggggggcgagtgtgtgccctgcaatggaccgtgcccc
aaaacctgcccgggcgttactgtcctgcatgccggcaacattgactcgttccggaattgt
acggtgatcgatggcaacattcgcattttggatcagaccttctcgggcttccaggatgtc
tatgccaactacacgatgggaccacgatacataccgctggatcccgagcgactggaggtg
ttctccacggtgaaggagatcaccgggtatctgaatatcgagggaacccacccgcagttc
cggaatctgtcgtacttccgcaatctggaaacaattcatggccgccagctgatggagagc
atgtttgccgctttggcgatcgttaagtcatccctgtacagcctggagatgcgcaatctg
aagcagattagttccggcagtgtggtcatccagcataatagagacctctgctacgtaagc
aatatccgttggccggccattcagaaggagcccgaacagaaggtgtgggtcaacgagaat
ctcagggcggatctatgcgagaaaaatggaaccatttgctcggatcagtgcaacgaggac
ggctgctggggagctggcacggatcagtgccttacctgcaagaacttcaatttcaatggc
acctgcatcgccgactgtggttatatatccaatgcctacaagtttgacaatagaacgtgc
aagatatgccatccagagtgccggacttgcaatggagctggagcagatcactgccaggag
tgcgtccatgtgagggacggtcagcactgtgtgtccgagtgcccgaagaacaagtacaac
gatcgtggtgtctgccgagagtgccacgccacctgcgatggatgcactgggcccaaggac
accatcggcattggagcgtgtacaacgtgcaatttggccattatcaacaatgacgccaca
gtaaaacgctgcctgctgaaggacgacaagtgccccgatgggtacttctgggagtatgtg
catccacaagagcagggatcgctaaagccattggccggcagagcagtttgccgaaagtgc
catcccctttgcgagctgtgcaccaactacggataccatgaacaggtgtgctccaagtgc
acccactacaagcgacgagagcagtgcgagaccgagtgtccggccgatcactacacggat
gaggagcagcgcgagtgcttccagtgccacccagaatgcaacggttgcactggtccgggt
gccgacgattgcaagtcttgtcgcaacttcaagttgttcgacgcgaatgagacgggtccc
tatgtgaactccacgatgttcaattgcacctcgaagtgtcccttggagatgcgacatgtg
aactatcagtacacggccattggaccctactgtgcagctagtccgccgaggagcagcaag
ataactgccaatctggatgtgaacatgatcttcattatcactggtgctgttctggtgccg
acgatctgcatcctctgcgtggtcacatacatttgtcggcaaaagcaaaaggccaagaaa
gaaacagtgaagatgaccatggctctgtccggctgtgaggattccgagccgctgcgtccc
tcgaacattggagccaatctatgcaagttgcgcattgtcaaggacgccgagttgcgcaag
ggcggagtcctcggaatgggagcctttggacgagtgtacaagggcgtttgggtgccggag
ggtgagaacgtcaagattccagtggccattaaggagctgctcaagtccacaggcgccgag
tcaagcgaagagttcctccgcgaagcctacatcatggcctctgtggagcacgttaatctg
ctgaagctcctggccgtctgcatgtcctcacaaatgatgctaatcacgcaactgatgccg
cttggctgcctgttggactatgtgcgaaataaccgggacaagatcggctctaaggctctg
ctcaactggagcacgcaaatcgccaagggcatgtcgtatctggaggagaagcgactggtc
cacagagacttggctgcccgcaatgtcctggtgcagactccctcgctggtgaagatcacc
gactttgggctggccaagttgctgagcagcgattccaatgagtacaaggctgctggcggc
aagatgcccatcaagtggttggcactggagtgcattcgcaatcgtgtattcaccagcaag
tccgatgtctgggcctttggtgtgacaatttgggaactgctgacctttggccagcgtcca
cacgagaacatccccgctaaggatattcccgatcttattgaagtcggtctgaagctggag
cagccggagatttgttcgctggacatttactgcacacttctctcgtgctggcacttggat
gccgccatgcgtccaaccttcaagcagctgactacggtctttgctgagttcgccagagat
ccgggtcgctatctggccattcccggggataagttcacccggctgccggcctacacgagt
caggatgagaaggatctcatccgaaaattggctcccaccaccgatgggtccgaagccatt
gcggaacccgatgactacctgcaacccaaggcagcacctggtcctagtcacagaaccgac
tgcacggatgagatacccaagctgaaccgctactgcaaggatcctagcaacaagaattcg
agtaccggagacgatgagacggattcgagtgcccgggaagtgggcgtgggtaatctgcgc
ctcgatctaccagtcgatgaggatgattacctgatgcccacatgccaaccggggcccaac
aacaacaacaacataaataatcccaatcaaaacaatatggcagctgtgggcgtggctgcc
ggctacatggatctcatcggagtgcccgttagtgtggacaatccggagtatctgctaaac
gcgcagacactgggtgttggggagtcgccgatacccacccagaccatcgggataccggtg
atgggagtcccgggcaccatggaggtcaaggtgccaatgccaggcagtgagccaacgagc
tccgatcacgagtactacaatgatacccaacgggagttgcagccactgcatcgaaaccgc
aacacggagacgagggtgtag |
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