Drosophila melanogaster (fruit fly): Dmel_CG18085 Help Entry Dmel_CG18085      CDS       T00030                                  Symbol sev Name (RefSeq) sevenless   KO K05088   proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1] Organism dme  Drosophila melanogaster (fruit fly) Pathway dme04013   MAPK signaling pathway - fly Brite KEGG Orthology (KO) [BR:dme00001]  09130 Environmental Information Processing   09132 Signal transduction    04013 MAPK signaling pathway - fly     Dmel_CG18085 (sev)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dme01001]     Dmel_CG18085 (sev) Enzymes [BR:dme01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      Dmel_CG18085 (sev) Protein kinases [BR:dme01001]  Receptor tyrosine kinases (RTK)   ROS family    Dmel_CG18085 (sev) Cytokine receptors [BR:dme04050]  Receptor tyrosine kinase   RTK class II (Insulin receptor family)    Dmel_CG18085 (sev) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr fn3 Pkinase Pur_ac_phosph_N Interfer-bind Motif Other DBs NCBI-GeneID:  32039 NCBI-ProteinID:  NP_511114 FlyBase:  FBgn0003366 UniProt:  P13368 LinkDB All DBs Position X:complement(11071441..11086299) Genome browser AA seq 2554 aa AA seqDB search MTMFWQQNVDHQSDEQDKQAKGAAPTKRLNISFNVKIAVNVNTKMTTTHINQQAPGTSSS SSNSQNASPSKIVVRQQSSSFDLRQQLARLGRQLASGQDGHGGISTILIINLLLLILLSI CCDVCRSHNYTVHQSPEPVSKDQMRLLRPKLDSDVVEKVAIWHKHAAAAPPSIVEGIAIS SRPQSTMAHHPDDRDRDRDPSEEQHGVDERMVLERVTRDCVQRCIVEEDLFLDEFGIQCE KADNGEKCYKTRCTKGCAQWYRALKELESCQEACLSLQFYPYDMPCIGACEMAQRDYWHL QRLAISHLVERTQPQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEE LDLEQEDQDASGETGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEV LYSPATPAYQTPPEGAPISAPVIEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEG NATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVAKGFVQTHSARNEKPAKDL TESVLLVGRRAVMWQSLEPAGENSMIYQSQEELADIAWSKREQQLWLLNVHGELRSLKFE SGQMVSPAQQLKLDLGNISSGRWVPRRLSFDWLHHRLYFAMESPERNQSSFQIISTDLLG ESTQKVGESFDLPVEQLEVDALNGWIFWRNEESLWRQDLHGRMIHRLLRIRQPGWFLVQP QHFIIHLMLPQEGKFLEISYDGGFKHPLPLPPPSNGAGNGPASSHWQSFALLGRSLLLPD SGQLILVEQQGQAASPSASWPLKNLPDCWAVILLVPESQPLTSAGGKPHSLKALLGAQAA KISWKEPERNPYQSADAARSWSYELEVLDVASQSAFSIRNIRGPIFGLQRLQPDNLYQLR VRAINVDGEPGEWTEPLAARTWPLGPHRLRWASRQGSVIHTNELGEGLEVQQEQLERLPG PMTMVNESVGYYVTGDGLLHCINLVHSQWGCPISEPLQHVGSVTYDWRGGRVYWTDLARN CVVRMDPWSGSRELLPVFEANFLALDPRQGHLYYATSSQLSRHGSTPDEAVTYYRVNGLE GSIASFVLDTQQDQLFWLVKGSGALRLYRAPLTAGGDSLQMIQQIKGVFQAVPDSLQLLR PLGALLWLERSGRRARLVRLAAPLDVMELPTPDQASPASALQLLDPQPLPPRDEGVIPMT VLPDSVRLDDGHWDDFHVRWQPSTSGGNHSVSYRLLLEFGQRLQTLDLSTPFARLTQLPQ AQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVERLATALQEANVSAVLRW DAPEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEHLQPDQTYHFQVEARVAA TGAAAGAASHALHVAPEVQAVPRVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEG EQRLLWVNEHVELLTHVPGSAPAKLARMRAEVLALAVDWIQRIVYWAELDATAPQAAIIY RLDLCNFEGKILQGERVWSTPRGRLLKDLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTD GSELEWATVQPLIRLHAGSLEPGSETLNLVDNQGKLCVYDVARQLCTASALRAQLNLLGE DSIAGQLAQDSGYLYAVKNWSIRAYGRRRQQLEYTVELEPEEVRLLQAHNYQAYPPKNCL LLPSSGGSLLKATDCEEQRCLLHLPMITASEDCPLPIPGVRYQLNLTLAKEPGSEEHDHG MEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASATPS PPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLET AGTHRLTGIKPGSGYSLWVQAHATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWA GTPDPLGSLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRYQCRLLLGYAATPGAPLYH GTAEVYETLGDAPSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDIRRR RRRRRRNSGGSLEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLE HGWGPYSEESERVAEPFVSPEKRGSLVLAIIAPAAIVSSCVLALVLVRKVQKRRLRAKKL LQQSRPSIWSNLSTLQTQQQLMAVRNRAFSTTLSDADIALLPQINWSQLKLLRFLGSGAF GEVYEGQLKTEDSEEPQRVAIKSLRKGASEFAELLQEAQLMSNFKHENIVCLVGICFDTE SISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYLEDMHFV HRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSPESLV DGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLL LLCWRTDPWERPSFRRCYNTLHAISTDLRRTQMASATADTVVSCSRPEFKVRFDGQPLEE HREHNERPEDENLTLREVPLKDKQLYANEGVSRL NT seq 7665 nt NT seq  +upstreamnt  +downstreamnt atgactatgttttggcaacaaaatgtagaccaccagtcggatgagcaggacaaacaggcg aagggtgcggcgcccacaaagagattgaacatcagcttcaatgtgaagatcgcggtgaat gtgaataccaagatgaccaccacccacatcaatcagcaggcacctggcacctcctcctcc tcgtcgaactcccagaatgcctcacccagcaagattgtggtccgccagcagagcagctcc ttcgatctacgtcagcaattggctcgcttaggccgccaattggccagtggccaggatggc catggcggcatatccaccatactgatcatcaatcttctcctgctcattctactctcgatc tgctgcgatgtctgccgatcgcacaactatacggtgcaccagagtcccgaacccgtctcc aaagaccaaatgcgcctgctgcgtcccaagctggacagcgatgtggtcgagaaggtggcc atctggcacaagcacgccgccgcagctccgccaagcattgtcgagggcatcgccatcagc agcaggccacagtcaacgatggcccatcatccagatgatcgagatcgggatcgtgatcct tcggaggaacagcatggcgtcgacgagcgaatggtcctggaacgcgtgaccagggattgt gtgcagcgctgcattgttgaggaggatctgtttctggacgaatttggaatacagtgcgaa aaggcggacaatggcgagaagtgctacaaaacacgatgcaccaagggctgtgcccagtgg tatcgcgccctcaaggagctggagtcctgccaggaggcctgcctgtccctccagttctac ccgtacgacatgccctgcatcggtgcctgcgagatggcccagcgggactactggcacctc cagcgactggccatcagccacctggtggagcggacgcagccgcagctggagcgagctcct cgggcggacggacagtccacgccactgaccatccgctgggcgatgcactttccggaacac tacctggccagcagacccttcaacattcagtaccagtttgtggatcaccacggcgaggag ctggatctcgagcaggaagaccaggatgcatccggagagacgggttccagtgcctggttt aacttagccgattacgactgtgacgagtattatgtgtgcgagatactggaggccctgata ccctacacacaatacaggttccgatttgagttgcctttcggcgagaatagagacgaagtc ctctactctccggccacgcccgcctaccaaacgccacccgagggcgcgcccatctcggct ccggtcatcgagcatctgatgggtctcgacgacagccacctggctgtccactggcatccc ggtcgcttcaccaatggacccatcgagggttaccgcctgcgtttgagttcctcggaggga aacgctacaagtgaacagctggttccggccggacgaggtagctacatcttttcccagcta caagccggcaccaactataccctggcgctgagcatgatcaacaaacagggtgagggtccg gtggccaagggatttgtgcagactcactccgctcgaaatgaaaagcctgccaaggatctg acagaaagtgtcctgctcgtcggacgaagggctgtgatgtggcaatcgctggaaccggct ggtgagaactccatgatctatcaatctcaggaggaattggctgatatcgcctggtcaaag cgggagcaacaactgtggctgctcaacgtccatggagagttgcgcagcttaaaatttgaa tccggccagatggtgagtccagcgcagcagctcaagctggatctgggaaacatatccagt ggaagatgggttcctcgcagattgagcttcgactggctgcatcatcgactgtacttcgct atggagtcgccagagcgaaaccaatccagctttcagattatcagcacagatttgctgggt gaatcaacgcagaaagtgggcgagtcctttgatctgcccgttgagcagttggaagtggat gccctgaatggctggattttctggaggaacgaggagtcgctgtggcgtcaggatctgcat ggtcgaatgatccatcgcctgttgaggatcaggcagcccggttggttcctggtgcagcca caacacttcatcatccatctaatgcttccacaggagggtaaattcctagagataagctac gatggtgggttcaagcatccactgccgctaccaccgccttcgaatggagctggaaatgga cctgcatccagccattggcaaagctttgccctgttgggtcgctccctgctcctgcccgat tctggtcagctgatcctggttgagcagcagggtcaggcagccagtcccagtgcctcatgg cctctaaagaacttgcccgactgttgggccgtgatactcctggtgccggaaagccaacca ctgaccagcgctggaggaaaaccgcacagcttgaaggccttgctgggagcccaggcggca aagatctcgtggaaggagccggaacgcaatccctaccaatcggcggatgcagcacgcagc tggagctacgaactggaagtgcttgatgtggccagccaaagtgcctttagcattcgcaat attcgtggacccatctttggactgcagcgcctgcagccggataatctctatcaactgcga gttagggcaataaacgtggatggagagccgggcgagtggactgaaccgttggctgcccgc acctggccactgggtccacatcgcttgagatgggccagccggcagggaagcgtcattcat accaacgagctgggcgagggcttggaagtgcagcaggaacagttggagcgactacccgga cccatgaccatggtgaatgaaagcgtgggctactacgtcactggcgacggtctactgcac tgcatcaatctggtgcacagccagtggggatgcccaatctcggagccactgcagcacgtg ggctcggtgacttacgactggcggggcggaagagtttattggacggatctggccaggaat tgcgtggtgcgcatggatccatggtcgggcagtcgggaactgttgcccgtcttcgaggcc aacttcctggcattggatccgcgtcaaggccacctgtactatgccaccagctctcagctg tcgcgacatggttccacgcccgatgaagcggtcacttattatcgtgttaatgggctggag ggaagcatcgcctcctttgtgctggacacccagcaggatcagctcttctggcttgttaaa ggctctggtgcactgcgtttgtatcgtgcgcccctgacagctggcggggattcactgcag atgatccagcagattaaaggcgtctttcaggctgtcccggacagtttgcagcttctgcgg cccttgggcgcacttctttggctggagcggagtggcaggagagctcgcttggtccgcctg gctgctcctctggatgtcatggagctaccgacaccggaccaggcctctcctgcctccgca ttgcaattattggacccacaaccattgcctccgcgggatgagggggttattccaatgacc gtgctcccggatagcgtgcgtctggacgatggccactgggacgacttccatgtgcgctgg cagccatccacttccggtggcaatcacagcgtctcctatcgtctgctcctcgagtttggc caaagactacaaaccttggatttgagcacaccatttgcccggctgacccaattgccgcag gctcaattgcagctaaagatcagcatcacaccgcgaaccgcgtggcgaagtggagacacc actcgggtgcagctcaccaccccgccggtggctcctagtcagcctcgtcgtctgcgcgtg ttcgtggagcgcttggccactgccctgcaggaggctaatgtgagtgctgtgctccgctgg gatgcgccggaacagggtcaggaggcgccgatgcaggcgctggagtatcacatcagctgt tgggtgggctcagagctgcacgaggagttgcgcctcaatcagagtgccctggaggcccgc gtagagcacctgcaaccggatcagacgtaccacttccaggtggaggcacgtgtggctgcc acgggagcggcagcgggcgcagctagtcatgccctccatgtggcaccggaggtgcaggcg gtgccacgcgtactctacgccaatgcagagtttattggcgaactggacctggacacacgg aatcgcaggcgactggtgcacacggccagtccggttgagcatctggtggggatcgaggga gagcagcgattgctgtgggtcaacgagcacgtggagctgctcacccatgtcccgggatca gctccagcaaagctggccagaatgagggccgaggtcttggcactggccgtggactggata cagcgtatcgtctactgggcggaactggatgctactgcaccgcaggcggcgataatctat cgcctggatctgtgcaactttgaagggaagatcctgcagggcgagcgggtgtggagcact cccaggggacggttgctgaaggatctggtggccctgccacaggcgcaatctctgatctgg ttggagtacgagcagggatctccgagaaatggttcgctccggggcagaaatctaaccgat ggctcggagctggagtgggcaacggttcagccgctaatccgtctgcatgctggaagctta gagcccggatcggagaccttgaacctggtggacaaccagggcaagctgtgtgtctacgat gtggcccgtcagctgtgcacggccagcgctttgcgggcacagctgaacttgctgggcgag gactccattgctggtcagttggcccaggattcgggatacctttacgccgtgaaaaactgg agcattcgtgcttatggtcgccggcgccagcagctggagtatacggtggaactggagccg gaagaggtgcgtctgctccaggcacacaactatcaggcctatccgcccaagaactgtctg ctccttccttcatccggcggatcccttttgaaagctaccgattgtgaggagcagagatgc ctattacacttacccatgatcacagcctccgaagattgtccactgcctattcctggcgtt agataccaactgaatcttacgttggccaaggagccgggatccgaggagcacgatcatggg atggagcccctgggacagtggctgctcggtgctggggaatcgttgaatcttacagacctg ctgcccttcacccgttatcgcgtgtctggaattttgagcagcttttaccaaaagaagttg gcattacccaccttggtgttggcaccactggagctccttaccgcctctgccacgccctcg cctccaaggaacttcagtgttcgtgtgcttagtcccagggaactggaggtcagctggttg ccgccggagcagctgcgtagcgaaagtgtctactacacgctccactggcaacaggaactg gatggtgaaaatgtccaggatcggcgggaatgggaggcacatgagcggcgactggagacg gcgggcactcatcgattgactggaatcaagccgggatctgggtatagcctgtgggttcag gcccatgccacgcccaccaagagcaacagcagcgagcggctgcatgtgcgtagtttcgcc gaattacccgagttgcagctcctggaactgggaccctattctctgagtctcacctgggcg ggaacaccggatccactgggatcgctgcagctcgaatgccgatcgtcggctgagcaactg cgtcgcaatgtggccggaaatcacactaagatggtggtggagccattgcagccacgcacc cgctaccagtgtcgcctgctcctgggctatgcggcgacgccgggagctccactgtaccat ggcactgcagaggtgtacgaaactctgggagatgcgcccagtcagccgggcaagccacaa ttggagcacatcgctgaggaggttttccgtgtcacctggacggcggcccgcggtaatgga gcacccattgctctctacaatctggaggcactccaggcgaggagcgacattcgccggagg cgcagaagaaggcgccgcaatagcggtggatcactagagcagttgccgtgggctgaggaa ccggtggtcgtggaggatcagtggctggacttctgcaacaccaccgagctgagctgcatt gtgaagagtctgcattcgagcaggttgctcctcttccgtgtgcgtgcgcggagcttggag cacggatggggaccttacagcgaggagagcgaacgggtggcggagcccttcgtttcgccg gagaagagaggatcactggtcctggccatcattgcgccggctgccatcgtttccagctgc gttctggcattggtgctcgttcgaaaagttcaaaagcgacgactgcgtgccaagaaactg cttcagcagagccgtcccagcatctggagcaacctgtccaccttgcagacgcaacagcag ctgatggccgtcaggaatcgcgccttctccaccacgctgagtgatgcggacatcgctctg ctgccccaaattaattggagtcaactgaagttgctccgatttcttggcagcggtgctttt ggtgaggtatacgagggtcagttgaagacggaggactccgaggagccgcaacgagtggcc atcaagagcctgcgcaagggagccagtgaatttgccgagctgcttcaggaggctcagctg atgagcaacttcaagcacgagaacattgtgtgcctggtgggaatctgcttcgacaccgag tccatatctctgattatggagcacatggaagcgggcgacttgctaagctacctacgtgcc gccagggctaccagcacccaggagccacaacccactgctggactctcgctctccgagctc ctggccatgtgcattgatgtggccaacggctgcagttatctggaggacatgcactttgtg catcgcgacctggcctgccggaactgtttggtcacggaatcgacgggcagcacggatcgt cggcgcaccgtgaagattggtgacttcggattggcgagggacatctacaagagcgactac taccgaaaggagggcgagggcctgctaccggtgcgctggatgtcgccggagagtctcgtc gacgggttgttcaccacacagtcggatgtgtgggcctttggagtgctctgctgggagatc ctcacactgggccagcagccgtatgcggcgaggaacaacttcgaggtgctggcccatgtc aaggagggcggacggctccagcagccgcccatgtgtacggagaagctttactccctgctc ctgctttgctggcgaacggatccgtgggagcgacccagtttccggcgctgctacaacaca ctccatgccatcagcaccgatttgcggcgcacccaaatggcctcggcaactgcggatacg gttgtcagctgctccaggccggagttcaaggtgcgattcgatggccagccgctggaggag catagagagcacaatgagcggccggaggatgagaacctgacgctgcgggaagtgccgctc aaggataagcaactgtatgcaaacgagggagtctcgcgactttag

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