Homo sapiens (human): 1024 Help Entry 1024              CDS       T01001                                  Symbol CDK8, IDDHBA, K35 Name (RefSeq) cyclin dependent kinase 8   KO K02208   cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23] Organism hsa  Homo sapiens (human) Disease H02463   Syndromic intellectual developmental disorder Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     1024 (CDK8)   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:hsa03021]     1024 (CDK8) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      1024 (CDK8)     2.7.11.23  [RNA-polymerase]-subunit kinase      1024 (CDK8) Protein kinases [BR:hsa01001]  Serine/threonine kinases: CMGC group   CDK family    1024 (CDK8) Transcription machinery [BR:hsa03021]  Eukaryotic type   RNA polymerase II system    Mediator complex     CDK-module      1024 (CDK8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kdo Motif Other DBs NCBI-GeneID:  1024 NCBI-ProteinID:  NP_001251 OMIM:  603184 HGNC:  1779 Ensembl:  ENSG00000132964 UniProt:  P49336 Structure PDBPDBj LinkDB All DBs Position 13:26254129..26405238 Genome browser AA seq 464 aa AA seqDB search MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY NT seq 1395 nt NT seq  +upstreamnt  +downstreamnt atggactatgactttaaagtgaagctgagcagcgagcgggagcgggtcgaggacctgttt gaatacgagggctgcaaagttggccgaggcacttatggtcacgtctacaaagccaagagg aaagatgggaaggatgataaagactatgctttaaaacaaatagaaggaactgggatctct atgtcggcatgtagagaaatagcattacttcgagagcttaagcatccaaacgtcatttct cttcaaaaggtgtttctgtctcatgctgataggaaggtgtggcttctgtttgactatgct gaacatgacctctggcatataatcaagtttcacagagcttctaaagcaaacaagaagcca gttcagttacctcggggaatggtgaagtcactattatatcagatcctagatggtattcac tacctgcatgctaactgggtgttgcacagagatttgaaacctgctaatattttagttatg ggtgaaggtcctgagcgaggaagagtaaaaattgctgacatgggctttgcccgattattt aattcacctttgaagcctttagcagatttggatccagtggttgttacattctggtaccga gcccctgaactacttcttggagcaaggcattataccaaagctattgatatttgggctata gggtgtatatttgcagaactactaacgtcagaaccaatatttcactgtcgacaagaggac atcaaaactagtaatccttatcaccatgaccagctggacagaatattcaatgtaatggga tttcctgcagataaagattgggaagatataaaaaagatgcctgaacattcaacattaatg aaagatttcagaagaaatacgtataccaactgcagccttatcaagtatatggaaaaacat aaagttaaaccagatagtaaagcattccacttgcttcagaagctgcttaccatggaccca ataaagcgaattacctcagaacaggctatgcaggacccctatttcttagaagacccactt cctacatcagacgtttttgccggttgtcaaatcccttacccaaaacgagaatttttaacg gaagaagaacctgatgacaaaggagacaaaaagaaccagcagcagcagcagggcaataac cacactaatggaactggccacccagggaatcaagacagcagtcacacacagggacccccg ttgaagaaagtgagagttgttcctcctaccactacctcaggtggacttatcatgacctca gactatcagcgttccaatccacatgctgcctatcccaaccctggaccaagcacatcacag ccgcagagcagcatgggatactcagctacctcccagcagcctccacagtactcacatcag acacatcggtactga

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