Homo sapiens (human): 1025 Help Entry 1025              CDS       T01001                                  Symbol CDK9, C-2k, CDC2L4, CTK1, PITALRE, TAK Name (RefSeq) cyclin dependent kinase 9   KO K02211   cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23] Organism hsa  Homo sapiens (human) Pathway hsa03250   Viral life cycle - HIV-1 hsa05202   Transcriptional misregulation in cancer Network nt06240  Transcription (cancer)   Element N00119   MLL-AF4 fusion to transcriptional activation Drug target Dinaciclib:  D09604 Enitociclib:  D12525 Istisociclib:  D12868 Zotiraciclib (DG03058):  D11599 D11600 Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03250 Viral life cycle - HIV-1     1025 (CDK9)  09160 Human Diseases   09161 Cancer: overview    05202 Transcriptional misregulation in cancer     1025 (CDK9)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     1025 (CDK9)   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:hsa03021]     1025 (CDK9) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      1025 (CDK9)     2.7.11.23  [RNA-polymerase]-subunit kinase      1025 (CDK9) Protein kinases [BR:hsa01001]  Serine/threonine kinases: CMGC group   CDK family    1025 (CDK9) Transcription machinery [BR:hsa03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Super elongation complex (SEC)      1025 (CDK9)     Brd4/P-TEFb complex      1025 (CDK9)     7SK RNP complex      1025 (CDK9) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Haspin_kinase ABC1 Motif Other DBs NCBI-GeneID:  1025 NCBI-ProteinID:  NP_001252 OMIM:  603251 HGNC:  1780 Ensembl:  ENSG00000136807 UniProt:  P50750 Structure PDBPDBj LinkDB All DBs Position 9:127786034..127790792 Genome browser AA seq 372 aa AA seqDB search MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFP ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL ISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP ATTNQTEFERVF NT seq 1119 nt NT seq  +upstreamnt  +downstreamnt atggcaaagcagtacgactcggtggagtgccctttttgtgatgaagtttccaaatacgag aagctcgccaagatcggccaaggcaccttcggggaggtgttcaaggccaggcaccgcaag accggccagaaggtggctctgaagaaggtgctgatggaaaacgagaaggaggggttcccc attacagccttgcgggagatcaagatccttcagcttctaaaacacgagaatgtggtcaac ttgattgagatttgtcgaaccaaagcttccccctataaccgctgcaagggtagtatatac ctggtgttcgacttctgcgagcatgaccttgctgggctgttgagcaatgttttggtcaag ttcacgctgtctgagatcaagagggtgatgcagatgctgcttaacggcctctactacatc cacagaaacaagatcctgcatagggacatgaaggctgctaatgtgcttatcactcgtgat ggggtcctgaagctggcagactttgggctggcccgggccttcagcctggccaagaacagc cagcccaaccgctacaccaaccgtgtggtgacactctggtaccggcccccggagctgttg ctcggggagcgggactacggcccccccattgacctgtggggtgctgggtgcatcatggca gagatgtggacccgcagccccatcatgcagggcaacacggagcagcaccaactcgccctc atcagtcagctctgcggctccatcacccctgaggtgtggccaaacgtggacaactatgag ctgtacgaaaagctggagctggtcaagggccagaagcggaaggtgaaggacaggctgaag gcctatgtgcgtgacccatacgcactggacctcatcgacaagctgctggtgctggaccct gcccagcgcatcgacagcgatgacgccctcaaccacgacttcttctggtccgaccccatg ccctccgacctcaagggcatgctctccacccacctgacgtccatgttcgagtacttggca ccaccgcgccggaagggcagccagatcacccagcagtccaccaaccagagtcgcaatccc gccaccaccaaccagacggagtttgagcgcgtcttctga

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