Homo sapiens (human): 11011 Help Entry 11011             CDS       T01001                                  Symbol TLK2, HsHPK, MRD57, PKU-ALPHA Name (RefSeq) tousled like kinase 2   KO K08864   tousled-like kinase [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Disease H00773   Autosomal dominant intellectual developmental disorder Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     11011 (TLK2) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      11011 (TLK2) Protein kinases [BR:hsa01001]  Serine/threonine kinases: Other   TLK family    11011 (TLK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr GIT_CC Motif Other DBs NCBI-GeneID:  11011 NCBI-ProteinID:  NP_001271262 OMIM:  608439 HGNC:  11842 Ensembl:  ENSG00000146872 UniProt:  Q86UE8 Structure PDBPDBj LinkDB All DBs Position 17:62470914..62615481 Genome browser AA seq 772 aa AA seqDB search MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ RNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPL PRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ KQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEE AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN NT seq 2319 nt NT seq  +upstreamnt  +downstreamnt atgatggaagaattgcatagcctggacccacgacggcaggaattattggaggccaggttt actggagtaggtgttagtaagggaccacttaatagtgagtcttccaaccagagcttgtgc agcgtcggatccttgagtgataaagaagtagagactcccgagaaaaagcagaatgaccag cgaaatcggaaaagaaaagctgaaccatatgaaactagccaagggaaaggcactcctagg ggacataaaattagtgattactttgagtttgctgggggaagcgcgccaggaaccagccct ggcagaagtgttccaccagttgcacgatcctcaccgcaacattccttatccaatccctta ccgcgacgagtagaacagcccctctatggtttagatggcagtgctgcaaaggaggcaacg gaggagcagtctgctctgccaaccctcatgtcagtgatgctagcaaaacctcggcttgac acagagcagctggcgcaaaggggagctggcctctgcttcacttttgtttcagctcagcaa aacagtccctcatctacgggatctggcaacacagagcattcctgcagctcccaaaaacag atctccatccagcacagacagacccagtccgacctcacaatagaaaaaatatctgcacta gaaaacagtaagaattctgacttagagaagaaggagggaagaatagatgatttattaaga gccaactgtgatttgagacggcagattgatgaacagcaaaagatgctagagaaatacaag gaacgattaaatagatgtgtgacaatgagcaagaaactccttatagaaaagtcaaaacaa gagaagatggcgtgtagagataagagcatgcaagaccgcttgagactgggccactttact actgtccgacacggagcctcatttactgaacagtggacagatggttatgcttttcagaat cttatcaagcaacaggaaaggataaattcacagagggaagagatagaaagacaacggaaa atgttagcaaagcggaaacctcctgccatgggtcaggcccctcctgcaaccaatgagcag aaacagcggaaaagcaagaccaatggagctgaaaatgaaacgccctcttctgggaataca gagctaaaggatacagccccagccttaggagcccacagtttacttaggttaacgttagca gaataccatgaacaagaagaaatcttcaaactcagattaggtcatcttaaaaaggaggaa gcagagatccaggcagagctggagagactagaaagggttagaaatctacatatcagggaa ctaaaaaggatacataatgaagataattcacaatttaaagatcatccaacgctaaatgac agatatttgttgttacatcttttgggtagaggaggtttcagtgaagtttacaaggcattt gatctaacagagcaaagatacgtagctgtgaaaattcaccagttaaataaaaactggaga gatgagaaaaaggagaattaccacaagcatgcatgtagggaataccggattcataaagag ctggatcatcccagaatagttaagctgtatgattacttttcactggatactgactcgttt tgtacagtattagaatactgtgagggaaatgatctggacttctacctgaaacagcacaaa ttaatgtcggagaaagaggcccggtccattatcatgcagattgtgaatgctttaaagtac ttaaatgaaataaaacctcccatcatacactatgacctcaaaccaggtaatattctttta gtaaatggtacagcgtgtggagagataaaaattacagattttggtctttcgaagatcatg gatgatgatagctacaattcagtggatggcatggagctaacatcacaaggtgctggtact tattggtatttaccaccagagtgttttgtggttgggaaagaaccaccaaagatctcaaat aaagttgatgtgtggtcggtgggtgtgatcttctatcagtgtctttatggaaggaagcct tttggccataaccagtctcagcaagacatcctacaagagaatacgattcttaaagctact gaagtgcagttcccgccaaagccagtagtaacacctgaagcaaaggcgtttattcgacga tgcttggcctaccgaaaggaggaccgcattgatgtccagcagctggcctgtgatccctac ttgttgcctcacatccgaaagtcagtctctacaagtagccctgctggagctgctattgca tcaacctctggggcgtccaataacagttcttctaattga

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