| Entry |
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| Symbol |
RIPK3, RIP3
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| Name |
(RefSeq) receptor interacting serine/threonine kinase 3
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| KO |
| K08847 | receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1] |
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| Organism |
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| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
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| Network |
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| Element |
| N01583 | Regulation of extrinsic apoptotic pathway, XIAP |
| N01621 | TNF-RIPK1/3 signaling pathway |
| N01625 | CYLD regulation of RIPK1/3 |
| N01631 | TNFSF10-RIPK1/3 signaling pathway |
| N01632 | FASLG-RIPK1/3 signaling pathway |
| N01633 | TLR3-RIPK3 signaling pathway |
| N01634 | TLR4-RIPK3 signaling pathway |
| N01650 | SQSTM1 regulation of RIPK1/3 |
| N01662 | IFN-RIPK1/3 signaling pathway |
| N01663 | CASP8 regulation of RIPK1/3 |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
11035 (RIPK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
11035 (RIPK3)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
11035 (RIPK3)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: TKL group
RIPK family [OT]
11035 (RIPK3)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
14:complement(24336025..24339991)
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| AA seq |
518 aa
MSCVKLWPSGAPAPLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISRE
VKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRL
LKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPG
GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRP
SLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST
VKDFLSQLRSSNRRFSIPESGQGGTEMDGFRRTIENQHSRNDVMVSEWLNKLNLEEPPSS
VPKKCPSLTKRSRAQEEQVPQAWTAGTSSDSMAQPPQTPETSTFRNQMPSPTSTGTPSPG
PRGNQGAERQGMNWSCRTPEPNPVTGRPLVNIYNCSGVQVGDNNYLTMQQTTALPTWGLA
PSGKGRGLQHPPPVGSQEGPKDPEAWSRPQGWYNHSGK |
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| NT seq |
1557 nt +upstreamnt +downstreamnt
atgtcgtgcgtcaagttatggcccagcggtgcccccgcccccttggtgtccatcgaggaa
ctggagaaccaggagctcgtcggcaaaggcgggttcggcacagtgttccgggcgcaacat
aggaagtggggctacgatgtggcggtcaagatcgtaaactcgaaggcgatatccagggag
gtcaaggccatggcaagtctggataacgaattcgtgctgcgcctagaaggggttatcgag
aaggtgaactgggaccaagatcccaagccggctctggtgactaaattcatggagaacggc
tccttgtcggggctgctgcagtcccagtgccctcggccctggccgctcctttgccgcctg
ctgaaagaagtggtgcttgggatgttttacctgcacgaccagaacccggtgctcctgcac
cgggacctcaagccatccaacgtcctgctggacccagagctgcacgtcaagctggcagat
tttggcctgtccacatttcagggaggctcacagtcagggacagggtccggggagccaggg
ggcaccctgggctacttggccccagaactgtttgttaacgtaaaccggaaggcctccaca
gccagtgacgtctacagcttcgggatcctaatgtgggcagtgcttgctggaagagaagtt
gagttgccaaccgaaccatcactcgtgtacgaagcagtgtgcaacaggcagaaccggcct
tcattggctgagctgccccaagccgggcctgagactcccggcttagaaggactgaaggag
ctaatgcagctctgctggagcagtgagcccaaggacagaccctccttccaggaatgccta
ccaaaaactgatgaagtcttccagatggtggagaacaatatgaatgctgctgtctccacg
gtaaaggatttcctgtctcagctcaggagcagcaataggagattttctatcccagagtca
ggccaaggagggacagaaatggatggctttaggagaaccatagaaaaccagcactctcgt
aatgatgtcatggtttctgagtggctaaacaaactgaatctagaggagcctcccagctct
gttcctaaaaaatgcccgagccttaccaagaggagcagggcacaagaggagcaggttcca
caagcctggacagcaggcacatcttcagattcgatggcccaacctccccagactccagag
acctcaactttcagaaaccagatgcccagccctacctcaactggaacaccaagtcctgga
ccccgagggaatcagggggctgagagacaaggcatgaactggtcctgcaggaccccggag
ccaaatccagtaacagggcgaccgctcgttaacatatacaactgctctggggtgcaagtt
ggagacaacaactacttgactatgcaacagacaactgccttgcccacatggggcttggca
ccttcgggcaaggggaggggcttgcagcaccccccaccagtaggttcgcaagaaggccct
aaagatcctgaagcctggagcaggccacagggttggtataatcatagcgggaaataa |
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