| Entry |
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| Symbol |
MAP3K8, AURA2, COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT
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| Name |
(RefSeq) mitogen-activated protein kinase kinase kinase 8
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| KO |
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| Organism |
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| Pathway |
| hsa04620 | Toll-like receptor signaling pathway |
| hsa04660 | T cell receptor signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
1326 (MAP3K8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
1326 (MAP3K8)
04660 T cell receptor signaling pathway
1326 (MAP3K8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
1326 (MAP3K8)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
1326 (MAP3K8)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: STE group
Other
1326 (MAP3K8)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
10:30434021..30461833
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| AA seq |
467 aa
MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERS
KSLLLSGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYGQRPQESGILLNMVITPQNGR
YQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVE
IQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKG
LDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVIL
CRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPG
MRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELP
ENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG |
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| NT seq |
1404 nt +upstreamnt +downstreamnt
atggagtacatgagcactggaagtgacaataaagaagagattgatttattaattaaacat
ttaaatgtgtctgatgtaatagacattatggaaaatctttatgcaagtgaagagccagca
gtttatgaacccagtctaatgaccatgtgtcaagacagtaatcaaaacgatgagcgttct
aagtctctgctgcttagtggccaagaggtaccatggttgtcatcagtcagatatggaact
gtggaggatttgcttgcttttgcaaaccatatatccaacactgcaaagcatttttatgga
caacgaccacaggaatctggaattttattaaacatggtcatcactccccaaaatggacgt
taccaaatagattccgatgttctcctgatcccctggaagctgacttacaggaatattggt
tctgattttattcctcggggcgcctttggaaaggtatacttggcacaagatataaagacg
aagaaaagaatggcgtgtaaactgatcccagtagatcaatttaagccatctgatgtggaa
atccaggcttgcttccggcacgagaacatcgcagagctgtatggcgcagtcctgtggggt
gaaactgtccatctctttatggaagcaggcgagggagggtctgttctggagaaactggag
agctgtggaccaatgagagaatttgaaattatttgggtgacaaagcatgttctcaaggga
cttgattttctacactcaaagaaagtgatccatcatgatattaaacctagcaacattgtt
ttcatgtccacaaaagctgttttggtggattttggcctaagtgttcaaatgaccgaagat
gtctattttcctaaggacctccgaggaacagagatttacatgagcccagaggtcatcctg
tgcaggggccattcaaccaaagcagacatctacagcctgggggccacgctcatccacatg
cagacgggcaccccaccctgggtgaagcgctaccctcgctcagcctatccctcctacctg
tacataatccacaagcaagcacctccactggaagacattgcagatgactgcagtccaggg
atgagagagctgatagaagcttccctggagagaaaccccaatcaccgcccaagagccgca
gacctactaaaacatgaggccctgaacccgcccagagaggatcagccacgctgtcagagt
ctggactctgccctcttggagcgcaagaggctgctgagtaggaaggagctggaacttcct
gagaacattgctgattcttcgtgcacaggaagcaccgaggaatctgagatgctcaagagg
caacgctctctctacatcgacctcggcgctctggctggctacttcaatcttgttcgggga
ccaccaacgcttgaatatggctga |
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