KEGG   Homo sapiens (human): 1612
Entry
1612              CDS       T01001                                 
Symbol
DAPK1, DAPK, ROCO3
Name
(RefSeq) death associated protein kinase 1
  KO
K08803  death-associated protein kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa05200  Pathways in cancer
hsa05219  Bladder cancer
Disease
H00022  Bladder cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    1612 (DAPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1612 (DAPK1)
  09162 Cancer: specific types
   05219 Bladder cancer
    1612 (DAPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1612 (DAPK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     1612 (DAPK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  DAPK family
   1612 (DAPK1)
SSDB
Motif
Pfam: Pkinase Ank_2 Ank Ank_5 Ank_4 Ank_3 PK_Tyr_Ser-Thr Death COR Kdo Ank_KRIT1 RIO1 ANK_LRRK2 ABC_tran O_Spanin_T7 Kinase-like Glycos_trans_3N AAA_23
Other DBs
NCBI-GeneID: 1612
NCBI-ProteinID: NP_001275658
OMIM: 600831
HGNC: 2674
Ensembl: ENSG00000196730
UniProt: P53355
Structure
LinkDB
Position
9:87497228..87708634
AA seq 1430 aa
MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED
IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFL
KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGT
PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEY
FSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA
ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL
QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA
RHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEET
PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAC
DKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEAN
CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAG
LLARLRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGKTTLVESLKCGLLRSFFRRRR
PRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAP
THHPHCSADDQSTKAIDIQNAYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHVVVF
SLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKNPLQVVLVATHADIMNVPRPAGG
EFGYDKDTSLLKEIRNRFGNDLHISNKLFVLDAGASGSKDMKVLRNHLQEIRSQIVSVCP
PMTHLCEKIISTLPSWRKLNGPNQLMSLQQFVYDVQDQLNPLASEEDLRRIAQQLHSTGE
INIMQSETVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYTVEDIQRLVPDSDVEE
LLQILDAMDICARDLSSGTMVDVPALIKTDNLHRSWADEEDEVMVYGGVRIVPVEHLTPF
PCGIFHKVQVNLCRWIHQQSTEGDADIRLWVNGCKLANRGAELLVLLVNHGQGIEVQVRG
LETEKIKCCLLLDSVCSTIENVMATTLPGLLTVKHYLSPQQLREHHEPVMIYQPRDFFRA
QTLKETSLTNTMGGYKESFSSIMCFGCHDVYSQASLGMDIHASDLNLLTRRKLSRLLDPP
DPLGKDWCLLAMNLGLPDLVAKYNTSNGAPKDFLPSPLHALLREWTTYPESTVGTLMSKL
RELGRRDAADFLLKASSVFKINLDGNGQEAYASSCNSGTSYNSISSVVSR
NT seq 4293 nt   +upstreamnt  +downstreamnt
atgaccgtgttcaggcaggaaaacgtggatgattactacgacaccggcgaggaacttggc
agtggacagtttgcggttgtgaagaaatgccgtgagaaaagcaccggcctccagtatgcc
gccaaattcatcaagaaaaggaggactaagtccagccggcggggtgtgagccgcgaggac
atcgagcgggaggtcagcatcctgaaggagatccagcaccccaatgtcatcaccctgcac
gaggtctatgagaacaagacggacgtcatcctgatcttggaactcgttgcaggtggcgag
ctgtttgacttcttagctgaaaaggaatctttaactgaagaggaagcaactgaatttctc
aaacaaattcttaatggtgtttactacctgcactcccttcaaatcgcccactttgatctt
aagcctgagaacataatgcttttggatagaaatgtccccaaacctcggatcaagatcatt
gactttgggttggcccataaaattgactttggaaatgaatttaaaaacatatttgggact
ccagagtttgtcgctcctgagatagtcaactatgaacctcttggtcttgaggcagatatg
tggagtatcggggtaataacctatatcctcctaagtggggcctccccatttcttggagac
actaagcaagaaacgttagcaaatgtatccgctgtcaactacgaatttgaggatgaatac
ttcagtaataccagtgccctagccaaagatttcataagaagacttctggtcaaggatcca
aagaagagaatgacaattcaagatagtttgcagcatccctggatcaagcctaaagataca
caacaggcacttagtagaaaagcatcagcagtaaacatggagaaattcaagaagtttgca
gcccggaaaaaatggaaacaatccgttcgcttgatatcactgtgccaaagattatccagg
tcattcctgtccagaagtaacatgagtgttgccagaagcgatgatactctggatgaggaa
gactcctttgtgatgaaagccatcatccatgccatcaacgatgacaatgtcccaggcctg
cagcaccttctgggctcattatccaactatgatgttaaccaacccaacaagcacgggaca
cctccattactcattgctgctggctgtgggaatattcaaatactacagttgctcattaaa
agaggctcgagaatcgatgtccaggataagggcgggtccaatgccgtctactgggctgct
cggcatggccacgtcgataccttgaaatttctcagtgagaacaaatgccctttggatgtg
aaagacaagtctggagagatggccctccacgtggcagctcgctatggccatgctgacgtg
gctcagttactgtgcagcttcggctcaaatcccaatatccaggacaaggaagaagaaacc
cccctgcactgtgctgcttggcacggctattactctgtggccaaagccctttgtgaagcc
ggctgtaacgtgaacatcaagaaccgagaaggagagacgcccctcctgacagcctctgcc
aggggctaccacgacatcgtggagtgtctggccgaacatggagccgaccttaatgcttgc
gacaaggacggacacattgcccttcatctggctgtaagacggtgtcagatggaggtaatc
aagactctcctcagccaagggtgtttcgtcgattatcaagacaggcacggcaatactccc
ctccatgtggcatgtaaagatggcaacatgcctatcgtggtggccctctgtgaagcaaac
tgcaatttggacatctccaacaagtatgggcgaacgcctctgcaccttgcggccaacaac
ggaatcctagacgtggtccggtatctctgtctgatgggagccagcgttgaggcgctgacc
acggacggaaagacggcagaagatcttgctagatcggaacagcacgagcacgtagcaggt
ctccttgcaagacttcgaaaggatacgcaccgaggactcttcatccagcagctccgaccc
acacagaacctgcagccaagaattaagctcaagctgtttggccactcgggatccgggaaa
accacccttgtagaatctctcaagtgtgggctgctgaggagctttttcagaaggcgtcgg
cccagactgtcttccaccaactccagcaggttcccaccttcacccctggcttctaagccc
acagtctcagtgagcatcaacaacctgtacccaggctgcgagaacgtgagtgtgaggagc
cgcagcatgatgttcgagccgggtcttaccaaagggatgctggaggtgtttgtggccccg
acccaccacccgcactgctcggccgatgaccagtccaccaaggccatcgacatccagaac
gcttatttgaatggagttggcgatttcagcgtgtgggagttctctggaaatcctgtgtat
ttctgctgttatgactattttgctgcaaatgatcccacgtcaatccatgttgttgtcttt
agtctagaagagccctatgagatccagctgaaccaagtgattttctggctcagtttcctg
aagtcccttgtcccagttgaagaacccatagccttcggtggcaagctgaagaacccactc
caagttgtcctggtggccacccacgctgacatcatgaatgttcctcgaccggctggaggc
gagtttggatatgacaaagacacatcgttgctgaaagagattaggaacaggtttggaaat
gatcttcacatttcaaataagctgtttgttctggatgctggggcttctgggtcaaaggac
atgaaggtacttcgaaatcatctgcaagaaatacgaagccagattgtttcggtctgtcct
cccatgactcacctgtgtgagaaaatcatctccacgctgccttcctggaggaagctcaat
ggacccaaccagctgatgtcgctgcagcagtttgtgtacgacgtgcaggaccagctgaac
cccctggccagcgaggaggacctcaggcgcattgctcagcagctccacagcacaggcgag
atcaacatcatgcaaagtgaaacagttcaggacgtgctgctcctggacccccgctggctc
tgcacaaacgtcctggggaagttgctgtccgtggagaccccacgggcgctgcaccactac
cggggccgctacaccgtggaggacatccagcgcctggtgcccgacagcgacgtggaggag
ctgctgcagatcctcgatgccatggacatctgcgcccgggacctgagcagcgggaccatg
gtggacgtcccagccctgatcaagacagacaacctgcaccgctcctgggctgatgaggag
gacgaggtgatggtgtatggtggcgtgcgcatcgtgcccgtggaacacctcacccccttc
ccatgtggcatctttcacaaggtccaggtgaacctgtgccggtggatccaccagcaaagc
acagagggcgacgcggacatccgcctgtgggtgaatggctgcaagctggccaaccgtggg
gccgagctgctggtgctgctggtcaaccacggccagggcattgaggtccaggtccgcggc
ctggagacggagaagatcaagtgctgcctgctgctggactcggtgtgcagcaccattgag
aacgtcatggccaccacgctgccagggctcctgaccgtgaagcattacctgagcccccag
cagctgcgggagcaccatgagcccgtcatgatctaccagccacgggacttcttccgggca
cagactctgaaggaaacctcactgaccaacaccatgggggggtacaaggaaagcttcagc
agcatcatgtgcttcgggtgtcacgacgtctactcacaggccagcctcggcatggacatc
catgcatcagacctgaacctcctcactcggaggaaactgagtcgcctgctggacccgccc
gaccccctggggaaggactggtgccttctcgccatgaacttaggcctccctgacctcgtg
gcaaagtacaacaccagtaacggggctcccaaggatttcctccccagccccctccacgcc
ctgctgcgggaatggaccacctaccctgagagcacagtgggcaccctcatgtccaaactg
agggagctgggtcgccgggatgccgcagactttttgctgaaggcatcctctgtgttcaaa
atcaacctggatggcaatggccaggaggcctatgcctcgagctgcaacagcggcacctct
tacaattccattagctctgttgtatcccggtga

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