Homo sapiens (human): 2047 Help Entry 2047              CDS       T01001                                  Symbol EPHB1, ELK, EPHT2, Hek6, NET Name (RefSeq) EPH receptor B1   KO K05110   Eph receptor B1 [EC:2.7.10.1] Organism hsa  Homo sapiens (human) Pathway hsa04360   Axon guidance Drug target Sitravatinib (DG03045):  D11140 D11541 Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09158 Development and regeneration    04360 Axon guidance     2047 (EPHB1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     2047 (EPHB1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      2047 (EPHB1) Protein kinases [BR:hsa01001]  Receptor tyrosine kinases (RTK)   EPH family [OT]    2047 (EPHB1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_1 SAM_2 Pur_ac_phosph_N ABC1 Ig_DSCAM-DSCAML_C Ephrin_rec_like VSP CRLF2-like_D2 cEGF DAP10 Haspin_kinase EGF_2 Motif Other DBs NCBI-GeneID:  2047 NCBI-ProteinID:  NP_004432 OMIM:  600600 HGNC:  3392 Ensembl:  ENSG00000154928 UniProt:  P54762 Structure PDBPDBj LinkDB All DBs Position 3:134795260..135260467 Genome browser AA seq 984 aa AA seqDB search MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQV CNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSV IATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDY GACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYC NGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPI CTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIIC KKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPP QHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFN SSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLP LIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTY EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG HQKKILNSIHSMRVQISQSPTAMA NT seq 2955 nt NT seq  +upstreamnt  +downstreamnt atggccctggattatctactactgctcctcctggcatccgcagtggctgcgatggaagaa acgttaatggacaccagaacggctactgcagagctgggctggacggccaatcctgcgtcc gggtgggaagaagtcagtggctacgatgaaaacctgaacaccatccgcacctaccaggtg tgcaatgtcttcgagcccaaccagaacaattggctgctcaccaccttcatcaaccggcgg ggggcccatcgcatctacacagagatgcgcttcactgtgagagactgcagcagcctccct aatgtcccaggatcctgcaaggagaccttcaacttgtattactatgagactgactctgtc attgccaccaagaagtcagccttctggtctgaggccccctacctcaaagtagacaccatt gctgcagatgagagcttctcccaggtggactttgggggaaggctgatgaaggtaaacaca gaagtcaggagctttgggcctcttactcggaatggtttttacctcgcttttcaggattat ggagcctgtatgtctcttctttctgtccgtgtcttcttcaaaaagtgtcccagcattgtg caaaattttgcagtgtttccagagactatgacaggggcagagagcacatctctggtgatt gctcggggcacatgcatccccaacgcagaggaagtggacgtgcccatcaaactctactgc aacggggatggggaatggatggtgcctattgggcgatgcacctgcaagcctggctatgag cctgagaacagcgtggcatgcaaggcttgccctgcagggacattcaaggccagccaggaa gctgaaggctgctcccactgcccctccaacagccgctcccctgcagaggcgtctcccatc tgcacctgtcggaccggttattaccgagcggactttgaccctccagaagtggcatgcact agcgtcccatcaggtccccgcaatgttatctccatcgtcaatgagacgtccatcattctg gagtggcaccctccaagggagacaggtgggcgggatgatgtgacctacaacatcatctgc aaaaagtgccgggcagaccgccggagctgctcccgctgtgacgacaatgtggagtttgtg cccaggcagctgggcctgacggagtgccgcgtctccatcagcagcctgtgggcccacacc ccctacacctttgacatccaggccatcaatggagtctccagcaagagtcccttcccccca cagcacgtctctgtcaacatcaccacaaaccaagccgccccctccaccgttcccatcatg caccaagtcagtgccactatgaggagcatcaccttgtcatggccacagccggagcagccc aatggcatcatcctggactatgagatccggtactatgagaaggaacacaatgagttcaac tcctccatggccaggagtcagaccaacacagcaaggattgatgggctgcggcctggcatg gtatatgtggtacaggtgcgtgcccgcactgttgctggctacggcaagttcagtggcaag atgtgcttccagactctgactgacgatgattacaagtcagagctgagggagcagctgccc ctgattgctggctcggcagcggccggggtcgtgttcgttgtgtccttggtggccatctct atcgtctgtagcaggaaacgggcttatagcaaagaggctgtgtacagcgataagctccag cattacagcacaggccgaggctccccagggatgaagatctacattgaccccttcacttac gaggatcccaacgaagctgtccgggagtttgccaaggagattgatgtatcttttgtgaaa attgaagaggtcatcggagcaggggagtttggagaagtgtacaaggggcgtttgaaactg ccaggcaagagggaaatctacgtggccatcaagaccctgaaggcagggtactcggagaag cagcgtcgggactttctgagtgaggcgagcatcatgggccagttcgaccatcctaacatc attcgcctggagggtgtggtcaccaagagtcggcctgtcatgatcatcacagagttcatg gagaatggtgcattggattctttcctcaggcaaaatgacgggcagttcaccgtgatccag cttgtgggtatgctcaggggcatcgctgctggcatgaagtacctggctgagatgaattat gtgcatcgggacctggctgctaggaacattctggtcaacagtaacctggtgtgcaaggtg tccgactttggcctctcccgctacctccaggatgacacctcagatcccacctacaccagc tccttgggagggaagatccctgtgagatggacagctccagaggccatcgcctaccgcaag ttcacttcagccagcgacgtttggagctatgggatcgtcatgtgggaagtcatgtcattt ggagagagaccctattgggatatgtccaaccaagatgtcatcaatgccatcgagcaggac taccggctgcccccacccatggactgtccagctgctctacaccagctcatgctggactgt tggcagaaggaccggaacagccggccccggtttgcggagattgtcaacaccctagataag atgatccggaacccggcaagtctcaagactgtggcaaccatcaccgccgtgccttcccag cccctgctcgaccgctccatcccagacttcacggcctttaccaccgtggatgactggctc agcgccatcaaaatggtccagtacagggacagcttcctcactgctggcttcacctccctc cagctggtcacccagatgacatcagaagacctcctgagaataggcatcaccttggcaggc catcagaagaagatcctgaacagcattcattctatgagggtccagataagtcagtcacca acggcaatggcatga

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