Homo sapiens (human): 22848 Help Entry 22848             CDS       T01001                                  Symbol AAK1 Name (RefSeq) AP2 associated kinase 1   KO K08853   AP2-associated kinase [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Drug target Pilavapadin (DG03336):  D13080 D13081 Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     22848 (AAK1)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     22848 (AAK1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      22848 (AAK1) Protein kinases [BR:hsa01001]  Serine/threonine kinases: Other   NAK family [OT]    22848 (AAK1) Membrane trafficking [BR:hsa04131]  Endocytosis   Clathrin-mediated endocytosis    Kinases     22848 (AAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1 APH Haspin_kinase Motif Other DBs NCBI-GeneID:  22848 NCBI-ProteinID:  NP_055726 OMIM:  616405 HGNC:  19679 Ensembl:  ENSG00000115977 UniProt:  Q2M2I8 Structure PDBPDBj LinkDB All DBs Position 2:complement(69457997..69643739) Genome browser AA seq 961 aa AA seqDB search MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP AQQQPAGTFYQQQQAQTQQFQAVHPATQKPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPV PQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNL ISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLID L NT seq 2886 nt NT seq  +upstreamnt  +downstreamnt atgaagaagtttttcgactcccggcgagagcagggcggctctggcctgggctccggctcc agcggaggagggggcagcacctcgggcctgggcagtggctacatcggaagagtcttcggc atcgggcgacagcaggtcacagtggacgaggtgttggcggaaggtggatttgctattgta tttctggtgaggacaagcaatgggatgaaatgtgccttgaaacgcatgtttgtcaacaat gagcatgatctccaggtgtgcaagagagaaatccagataatgagggatctttcagggcac aagaatattgtgggttacattgattctagtatcaacaacgtgagtagcggtgatgtatgg gaagtgctcattctgatggacttttgtagaggtggccaggtggtaaacctgatgaaccag cgcctgcaaacaggctttacagagaatgaagtgctccagatattttgtgatacctgtgaa gctgttgcccgcctgcatcagtgcaaaactcctattatccaccgggacctgaaggttgaa aacatcctcttgcatgaccgaggccactatgtcctgtgtgactttggaagcgccaccaac aaattccagaatccacaaactgagggagtcaatgcagtagaagatgagattaagaaatac acaacgctgtcctatcgagcaccagaaatggtcaacctgtacagtggcaaaatcatcact acgaaggcagacatttgggctcttggatgtttgttgtataaattatgctacttcactttg ccatttggggaaagtcaggtggcaatttgtgatggaaacttcacaattcctgataattct cgatattctcaagacatgcactgcctaattaggtatatgttggaaccagaccctgacaaa aggccggatatttaccaggtgtcctacttctcatttaagctactcaagaaagagtgccca attccaaatgtacagaactctcccattcctgcaaagcttcctgaaccagtgaaagccagt gaggcagctgcaaaaaagacccagccaaaggccagactgacagatcccattcccaccaca gagacttcaattgcaccccgccagaggcctaaagctgggcagactcagccgaacccagga atccttcccatccagccagcgctgacaccccggaagagggccactgttcagcccccacct caggctgcaggatccagcaatcagcctggccttttagccagtgttccccaaccaaaaccc caagccccacccagccagcctctgccgcaaactcaggccaagcagccacaggctcctccc actccacagcagacgccttctactcaggcccagggtctgcccgctcaggcccaggccaca ccccagcaccagcagcaactcttcctcaagcagcaacagcagcagcaacagccaccgcca gcacagcagcagccggcaggcacgttttaccagcagcagcaggcccagactcagcagttt caggcagtacatccagcaacccagaaaccagcaattgctcagttccctgtggtgtcccaa ggaggctctcaacagcagctaatgcagaatttctaccagcagcagcagcagcagcaacaa caacagcaacagcaacagctggccacagccctgcatcaacaacagctgatgactcagcag gctgccttgcagcaaaagcccactatggcagcaggacagcagccccagccacagccagct gcagccccacagccagcccctgcccaggagccagcgattcaagccccagtaagacaacag ccaaaggttcagacaaccccacctcctgccgtccaggggcagaaagttggatctctcact ccaccctcatcccccaaaacccaacgtgctgggcacaggcgtattctcagtgacgtaacc cacagtgcagtctttggggtccctgccagcaaatcaacccagctgctccaggcagctgca gctgaggccagtctcaataagtccaagtctgcaaccaccactccatcaggctctcctcgg acctctcaacaaaacgtttataatccttcagaagggtctacgtggaatccctttgatgac gataatttctccaaactcacagctgaagaactgctaaacaaggactttgccaagcttggg gaaggcaaacatcccgagaagcttggaggctcagctgagagtttgatcccaggctttcaa tcaacccaaggtgatgcttttgctacgacctcattttctgctggaactgctgaaaaaagg aagggtgggcagactgtggactctggcctcccgcttctaagcgtgtctgatcctttcatt cctcttcaagtacctgatgcaccagaaaaactaattgagggactcaaatctcctgacact tctcttctgctccctgacctcttgcctatgacagatccttttggtagcacttctgatgct gtaattgaaaaagctgatgttgctgttgagagtctcataccaggactggagcccccagtt ccccagcgcctcccatctcagacggaatctgtgacctcgaatcgcacagattctctcacc ggggaagattccctgcttgattgctctctgctctctaaccctactactgaccttctggaa gagtttgcccccacagcaatctctgctccagtccataaagctgcagaagatagtaatctc atctcaggttttgatgtccctgagggctcggacaaggtggctgaagatgagtttgaccct attcctgtattgataaccaaaaacccacaaggtgggcactctagaaacagcagtgggagc tctgagtccagtcttcccaacctagccaggtctttactgctggtggatcagctcatagac ctgtag

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