KEGG   Homo sapiens (human): 23031
Entry
23031             CDS       T01001                                 
Symbol
MAST3, DEE108
Name
(RefSeq) microtubule associated serine/threonine kinase 3
  KO
K08789  MAST-subfamily protein kinase [EC:2.7.11.37]
Organism
hsa  Homo sapiens (human)
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    23031 (MAST3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.37  MAST-subfamily protein kinase
     23031 (MAST3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  MAST family [OT]
   23031 (MAST3)
SSDB
Motif
Pfam: DUF1908 Pkinase PK_Tyr_Ser-Thr PDZ_6 PDZ PDZ_2 ABC1 Kinase-like APH PDZ_Tricorn ACTL7A_N Haspin_kinase
Other DBs
NCBI-GeneID: 23031
NCBI-ProteinID: NP_055831
OMIM: 612258
HGNC: 19036
Ensembl: ENSG00000099308
UniProt: O60307
Structure
LinkDB
Position
19:18097778..18151687
AA seq 1309 aa
MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD
SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP
TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF
PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL
EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA
EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR
KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT
FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY
LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV
CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP
EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE
AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP
TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT
ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH
ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS
ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY
GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV
ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKIS
KQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSA
SPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPR
SPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERR
DSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD
NT seq 3930 nt   +upstreamnt  +downstreamnt
atggacgagtcgagcctcctgcggcgccgcgggctccagaaggagctgagcctgccacgc
cgaggacgtggctgccgcagcgggaaccgcaagagcttggtggtaggaacgccctccccg
accctctcccggcccctgtcgccattgtcggtcccaacggcaggcagcagccccttggat
agtcctcggaatttctcggctgcctctgccctaaatttcccctttgcccggagggcagac
ggcagaagatggtccctcgcgtctctcccatcttccggctatggaaccaacacacccagc
tccaccctctcgtcaagctcatcctcccgggaacgtctccaccagcttcccttccagccg
acgccggacgagctgcacttcctgtccaagcacttccgcagctcagagaatgtgcttgat
gaggaaggcggccggtcaccccgcctccgaccccgctctcgcagtctcagcccgggccgt
gcaacggggaccttcgacaatgagattgtcatgatgaatcacgtgtaccgggagaggttc
cccaaggccacagcacagatggagggccgtctgcaggagttcctgacggcctacgcgccc
ggcgcccggctggcgctggctgatggcgtcttgggcttcatccaccaccagatcgtcgag
ctggcccgagactgcttggccaagtctggcgagaacctcgtcacctcccgctacttccta
gagatgcaggagaagctggagcggcttctgcaggatgcccatgagcgttcggacagtgag
gaggtcagcttcatcgtccagcttgtccggaaactgctgatcatcatctcacggccagct
cggctgctggagtgtctggagtttgaccctgaggaattttaccacctgctggaggcggct
gagggccatgcgcgggagggccaaggcattaagactgaccttccacagtacatcattggg
cagctgggcctggccaaggaccccctggaggagatggtgccactgagtcacctcgaagaa
gaacagcccccagcacctgagtccccagagagccgcgccctggtcggccagtcacggagg
aagccatgcgaaagcgactttgagaccatcaaactcattagcaacggagcctatggggcc
gtctacctggtgcggcaccgtgacacacggcagcgctttgccatcaagaagatcaacaaa
cagaacttgatcctgcgtaaccagatccagcaggtctttgtggagcgtgacattctcacc
tttgccgagaacccctttgtggtcagcatgttctgctcctttgagacccggcgccaccta
tgtatggtcatggaatacgtggaaggcggcgactgcgccacgctcctgaagaacatgggc
ccgctgcccgtggacatggcccgcctgtacttcgccgagacggtgttggcgctggagtac
ctgcataactatggcatcgtgcaccgtgacctcaaaccagacaatctgctcatcacctcg
cttggccacatcaagctcacggacttcggcctgtccaagatcggcctcatgagcatggcc
accaacctctatgagggccacatcgagaaggacgcccgagagttcatcgacaagcaggtg
tgtgggacgccggagtacatagcccccgaggtgatcttccgccagggctatgggaagcca
gtggactggtgggccatgggcgtcgtcctctatgagtttctggtgggctgcgtgcctttc
tttggagatacccccgaggaactcttcggtcaggtggtcagcgatgagatcatgtggcca
gagggagatgaggcccttccagcagacgcccaggacctcatcaccaggttgctccggcag
agcccgctggaccgtctgggcactggtggcacccacgaagtgaagcagcacccctttttc
ctggccctggactgggcagggcttctccgacacaaagccgagttcgtgccccagctcgaa
gctgaggatgataccagctactttgacacacgttcggaacgttaccgccatctgggctcc
gaggacgacgagaccaatgatgaagaatcgtccacagagatcccccagttctcctcctgc
tcccaccggttcagcaaggtctacagcagctctgagttcctggccgtccagcccactcct
accttcgctgaaaggagcttcagtgaagaccgggaggaggggtgggagcgcagcgaagtg
gactatggccgccggctgagtgctgacatccggctgaggtcctggacatcctctggatcc
tcctgtcagtcatcttcgtcccagcccgagcggggtcccagcccatctctcctgaatacc
atcagcctggacacaatgcccaagtttgccttctcatcagaggatgagggggtaggccca
ggccctgcaggccccaagaggcccgtcttcattctaggggagcctgaccccccaccagcg
gccaccccagtgatgcccaagccctcgagcctttctgccgacacagctgctctcagccac
gcccgcctacggagcaatagcatcggcgcccgacactccacaccaaggcctctggatgcc
ggccggggccgccgccttgggggcccaagagacccagcccctgagaagtccagagcctcc
tccagcggtggcagtggtggcggcagtgggggccgcgtgcccaagtcagcctctgtctct
gccctgtccctcatcatcacggcagatgatggcagcggcggccccctcatgagccccctt
tccccgcgctctctgtcctcgaacccgtcgtcccgtgactcttcgccgagccgagacccg
tcccccgtgtgtggcagcctgcggccccccatcgttatccacagctctggcaagaagtac
ggcttcagcctgcgggcgatccgcgtctacatgggtgatagcgacgtctacactgtgcac
cacgtcgtctggagtgtggaggacggaagccccgcccaggaggcgggcctgcgggctggg
gacctcatcacccacatcaacggggagtcagtgctggggctggtgcacatggacgtcgtg
gagctgctgctgaagagcggcaacaagatatccctgcggaccacagccctggagaacacc
tccatcaaggtgggccccgcccggaagaatgtggccaagggccgcatggcacgcaggagc
aagaggagccgtcggcgggagacccaggatcggcggaagtcacttttcaagaagatctcc
aagcagacctccgtgctgcacaccagccgcagcttctcctccggactccaccactcactg
tcatccagtgagagcctccccggctcgcccacccacagcctctcccccagccccaccact
ccctgccgaagcccagcccctgatgtcccagcagataccactgcatccccacccagcgca
tccccgagctccagcagccccgcctccccagctgctgctggccacacccgccccagctcc
ctgcacggcctggctgccaagcttgggccaccccgccccaagactggccgccgcaagtcc
accagcagcatcccgccctccccgctggcctgcccgcccatctccgcgcccccaccccgc
tcgccctcgcccctgcccgggcacccgcccgcacctgcccgatccccgcggctgcgccgg
ggccagtcagctgacaagctgggcacaggggagcggctggatggggaggcggggcggcgc
actcgtgggccagaggccgagctcgtggtcatgcggcggctgcacctgtccgagcgccga
gactccttcaagaagcaggaggccgtgcaggaggttagcttcgatgagccgcaggaggag
gccactgggctgcccacctcagtgccacagatcgccgtggagggcgaggaagccgtgcca
gtagctctcgggcccaccggaagagactga

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