Homo sapiens (human): 23387 Help Entry 23387             CDS       T01001                                  Symbol SIK3, L19, QSK, SEMDK, SIK-3 Name (RefSeq) SIK family kinase 3   KO K19009   serine/threonine-protein kinase SIK3 [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Disease H02187   Spondyloepimetaphyseal dysplasia Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     23387 (SIK3) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      23387 (SIK3) Protein kinases [BR:hsa01001]  Serine/threonine kinases: CAMK group   CAMKL family    23387 (SIK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr UBA_SIK3 Kinase-like Haspin_kinase ABC1 Kdo Motif Other DBs NCBI-GeneID:  23387 NCBI-ProteinID:  NP_079440 OMIM:  614776 HGNC:  29165 Ensembl:  ENSG00000160584 UniProt:  Q9Y2K2 Structure PDBPDBj LinkDB All DBs Position 11:complement(116843402..117098428) Genome browser AA seq 1321 aa AA seqDB search MAAAAASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMP ARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKML CHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH CRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYD GPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVL DPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDK EQTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRLGALPSMPRALAFQAPVNIQAEQAGTA MNISVPQVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVM EDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLL NGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEA VQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQK MYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTH QLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMIQPHGAASSSQFQGLPSRSAIFQQ QPENCSSPPNVALTCLGMQQPAQSQQVTIQVQEPVDMLSNMPGTAAGSSGRGISISPSAG QMQMQHRTNLMATLSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSR GSPSSYSPSTGVGFSPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYT RHQQVPHILQGLLSPRHSLTGHSDIRLPPTEFAQLIKRQQQQRQQQQQQQQQQEYQELFR HMNQGDAGSLAPSLGGQSMTERQALSYQNADSYHHHTSPQHLLQIRAQECVSQASSPTPP HGYAHQPALMHSESMEEDCSCEGAKDGFQDSKSSSTLTKGCHDSPLLLSTGGPGDPESLL GTVSHAQELGIHPYGHQPTAAFSKNKVPSREPVIGNCMDRSSPGQAVELPDHNGLGYPAR PSVHEHHRPRALQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGS QQFQDGENEECGASLGGHEHPDLSDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAG V NT seq 3966 nt NT seq  +upstreamnt  +downstreamnt atggcggcggcggcggcgagcggagctggcggggctgccggggccgggactgggggagcc gggcccgcgggccgcctgctgcctccgcccgcgccggggtccccagccgcccccgctgcc gtgtcccctgcggccggccagccgcgtcccccagccccggcctcccgcggacccatgccc gcccgtatcggctactacgagatcgaccgcaccatcggcaagggcaacttcgcggtggtc aagcgggccacgcacctcgtcaccaaggccaaggttgctatcaagatcatagataagacc cagctggatgaagaaaacttgaagaagattttccgggaagttcaaattatgaagatgctt tgccacccccatatcatcaggctctaccaggttatggagacagaacggatgatttatctg gtgacagaatatgctagtggaggggaaatatttgaccacctggtggcccatggtagaatg gcagaaaaggaggcacgtcggaagttcaaacagatcgtcacagctgtctatttttgtcac tgtcggaacattgttcatcgtgatttaaaagctgaaaatttacttctggatgccaatctg aatatcaaaatagcagattttggtttcagtaacctcttcactcctgggcagctgctgaag acctggtgtggcagccctccctatgctgcacctgaactctttgaaggaaaagaatatgat gggcccaaagtggacatctggagccttggagttgtcctctacgtgcttgtgtgcggtgcc ctgccatttgatggaagcacactgcagaatctgcgggcccgcgtgctgagtggaaagttc cgcatcccattttttatgtccacagaatgtgagcatttgatccgccatatgttggtgtta gatcccaataagcgcctctccatggagcagatctgcaagcacaagtggatgaagctaggg gacgccgatcccaactttgacaggttaatagctgaatgccaacaactaaaggaagaaaga caggtggaccccctgaatgaggatgtcctcttggccatggaggacatgggactggacaaa gaacagacactgcagtcattaagatcagatgcctatgatcactatagtgcaatctacagc ctgctgtgtgatcgacataagagacataaaaccctgcgtctcggagcacttcctagcatg ccccgagccctggcctttcaagcaccagtcaatatccaggcggagcaggcaggtactgct atgaacatcagcgttccccaggtgcagctgatcaacccagagaaccaaattgtggagccg gatgggacactgaatttggacagtgatgagggtgaagagccttcccctgaagcattggtg cgctatttgtcaatgaggaggcacacagtgggtgtggctgacccacgcacggaagttatg gaagatctgcagaagctcctacctggctttcctggagtcaacccccaggctccattcctg caggtggcccctaatgtgaacttcatgcacaacctgttgcctatgcaaaacttgcaacca accgggcaacttgagtacaaggagcagtctctcctacagccgcccacgctacagctgttg aatggaatgggcccccttggccggagggcatcagatggaggagccaacatccaactgcat gcccagcagctgctgaagcgcccacggggaccctctccgcttgtcaccatgacaccagca gtgccagcagttacccctgtggacgaggagagctcagacggggagccagaccaggaagct gtgcagagctctacctacaaggactccaacactctgcacctccctacggagcgtttctcc cctgtgcgccggttctcagatggggctgcgagcatccaggccttcaaagctcacctggaa aaaatgggcaacaacagcagcatcaaacagctgcagcaggagtgtgagcagctgcagaag atgtacggggggcagattgatgaaagaaccctggagaagacccagcagcagcatatgtta taccagcaggagcagcaccatcaaattctccagcaacaaattcaagactctatctgtcct cctcagccatctccacctcttcaggctgcatgtgaaaatcagccagccctccttacccat cagctccagaggttaaggattcagccttcaagcccaccccccaaccaccccaacaaccat ctcttcaggcagcccagtaatagtcctccccccatgagcagtgccatgatccagcctcac ggggctgcatcttcttcccagtttcaaggcttaccttcccgcagtgcaatctttcagcag caacctgagaactgttcctctcctcccaacgtggcactaacctgcttgggtatgcagcag cctgctcagtcacagcaggtcaccatccaagtccaagagcctgttgacatgctcagcaac atgccaggcacagctgcaggctccagtgggcgcggcatctccatcagccccagtgctggt cagatgcagatgcagcaccgtaccaacctgatggccaccctcagctatgggcaccgtccc ttgtccaagcagctgagtgctgacagtgcagaggctcacagcttgaacgtgaatcggttc tcccctgctaactacgaccaggcgcatttacacccccatctgttttcggaccagtcccgg ggttcccccagcagctacagcccttcaacaggagtggggttctctccaacccaagccctg aaagtccctccacttgaccaattccccaccttccctcccagtgcacatcagcagccgcca cactataccacgtcggcactacagcaggccctgctgtctcccacgccgccagactataca agacaccagcaggtaccccacatccttcaaggactgctttctccccggcattcgctcacc ggccactcggacatccggctgcccccaacagagtttgcacagctcattaaaaggcagcag caacaacggcagcagcagcagcaacagcagcaacagcaagaataccaggaactgttcagg cacatgaaccaaggggatgcggggagtctggctcccagccttgggggacagagcatgaca gagcgccaggctttatcttatcaaaatgctgactcttatcaccatcacaccagcccccag catctgctacaaatcagggcacaagaatgtgtctcacaggcttcctcacccaccccgccc cacgggtatgctcaccagccggcactgatgcattcagagagcatggaggaggactgctcg tgtgagggggccaaggatggcttccaagacagtaagagttcaagtacattgaccaaaggt tgccatgacagccctctgctcttgagtaccggtggacctggggaccctgaatctttgcta ggaactgtgagtcatgcccaagaattggggatacatccctatggtcatcagccaactgct gcattcagtaaaaataaggtgcccagcagagagcctgtcatagggaactgcatggataga agttctccaggacaagcagtggagctgccggatcacaatgggctcgggtacccagcacgc ccctccgtccatgagcaccacaggccccgggccctccagagacaccacacgatccagaac agcgacgatgcttatgtacagctggataacttgccaggaatgagtctcgtggctgggaaa gcacttagctctgcccggatgtcggatgcagttctcagtcagtcttcgctcatgggcagc cagcagtttcaggatggggaaaatgaggaatgtggggcaagcctgggaggtcatgagcac ccagacctgagtgatggcagccagcatttaaactcctcttgctatccatctacgtgtatt acagacattctgctcagctacaagcaccccgaagtctccttcagcatggagcaggcaggc gtgtaa

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