Homo sapiens (human): 3984 Help Entry 3984              CDS       T01001                                  Symbol LIMK1, LIMK, LIMK-1 Name (RefSeq) LIM domain kinase 1   KO K05743   LIM domain kinase 1 [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Pathway hsa04360   Axon guidance hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05135   Yersinia infection hsa05170   Human immunodeficiency virus 1 infection Network nt06161  Human immunodeficiency virus 1 (HIV-1)   Element N00433   CXCR4-GNB/G-RAC signaling pathway Disease H01439   Williams-Beuren syndrome Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     3984 (LIMK1)   09158 Development and regeneration    04360 Axon guidance     3984 (LIMK1)  09160 Human Diseases   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     3984 (LIMK1)   09171 Infectious disease: bacterial    05135 Yersinia infection     3984 (LIMK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     3984 (LIMK1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      3984 (LIMK1) Protein kinases [BR:hsa01001]  Serine/threonine kinases: TKL group   LISK family [OT]    3984 (LIMK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase LIM PDZ Kdo PDZ_6 ABC1 Haspin_kinase RIO1 PDZ_2 APH Motif Other DBs NCBI-GeneID:  3984 NCBI-ProteinID:  NP_002305 OMIM:  601329 HGNC:  6613 Ensembl:  ENSG00000106683 UniProt:  P53667 Structure PDBPDBj LinkDB All DBs Position 7:74083804..74122525 Genome browser AA seq 647 aa AA seqDB search MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS HQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGD GDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSV SIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEID LLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSID RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRE TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGT LRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFG LARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLC EIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL EHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD NT seq 1944 nt NT seq  +upstreamnt  +downstreamnt atgaggttgacgctactttgttgcacctggagggaagaacgtatgggagaggaaggaagc gagttgcccgtgtgtgcaagctgcggccagaggatctatgatggccagtacctccaggcc ctgaacgcggactggcacgcagactgcttcaggtgttgtgactgcagtgcctccctgtcg caccagtactatgagaaggatgggcagctcttctgcaagaaggactactgggcccgctat ggcgagtcctgccatgggtgctctgagcaaatcaccaagggactggttatggtggctggg gagctgaagtaccaccccgagtgtttcatctgcctcacgtgtgggacctttatcggtgac ggggacacctacacgctggtggagcactccaagctgtactgcgggcactgctactaccag actgtggtgacccccgtcatcgagcagatcctgcctgactcccctggctcccacctgccc cacaccgtcaccctggtgtccatcccagcctcatctcatggcaagcgtggactttcagtc tccattgaccccccgcacggcccaccgggctgtggcaccgagcactcacacaccgtccgc gtccagggagtggatccgggctgcatgagcccagatgtgaagaattccatccacgtcgga gaccggatcttggaaatcaatggcacgcccatccgaaatgtgcccctggacgagattgac ctgctgattcaggaaaccagccgcctgctccagctgaccctcgagcatgaccctcacgat acactgggccacgggctggggcctgagaccagccccctgagctctccggcttatactccc agcggggaggcgggcagctctgcccggcagaaacctgtcttgaggagctgcagcatcgac aggtctccgggcgctggctcactgggctccccggcctcccagcgcaaggacctgggtcgc tctgagtccctccgcgtagtctgccggccacaccgcatcttccggccgtcggacctcatc cacggggaggtgctgggcaagggctgcttcggccaggctatcaaggtgacacaccgtgag acaggtgaggtgatggtgatgaaggagctgatccggttcgacgaggagacccagaggacg ttcctcaaggaggtgaaggtcatgcgatgcctggaacaccccaacgtgctcaagttcatc ggggtgctctacaaggacaagaggctcaacttcatcactgagtacatcaagggcggcacg ctccggggcatcatcaagagcatggacagccagtacccatggagccagagagtgagcttt gccaaggacatcgcatcagggatggcctacctccactccatgaacatcatccaccgagac ctcaactcccacaactgcctggtccgcgagaacaagaatgtggtggtggctgacttcggg ctggcgcgtctcatggtggacgagaagactcagcctgagggcctgcggagcctcaagaag ccagaccgcaagaagcgctacaccgtggtgggcaacccctactggatggcacctgagatg atcaacggccgcagctatgatgagaaggtggatgtgttctcctttgggatcgtcctgtgc gagatcatcgggcgggtgaacgcagaccctgactacctgccccgcaccatggactttggc ctcaacgtgcgaggattcctggaccgctactgccccccaaactgccccccgagcttcttc cccatcaccgtgcgctgttgcgatctggaccccgagaagaggccatcctttgtgaagctg gaacactggctggagaccctccgcatgcacctggccggccacctgccactgggcccacag ctggagcagctggacagaggtttctgggagacctaccggcgcggcgagagcggactgcct gcccaccctgaggtccccgactga

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