Homo sapiens (human): 410 Help Entry 410               CDS       T01001                                  Symbol ARSA, ASA, MLD Name (RefSeq) arylsulfatase A   KO K01134   arylsulfatase A [EC:3.1.6.8] Organism hsa  Homo sapiens (human) Pathway hsa00600   Sphingolipid metabolism hsa01100   Metabolic pathways hsa04142   Lysosome Network nt06014  Sphingolipid degradation   Element N00647   Hydrolysis of galactosylceramide sulfate Disease H00127   Metachromatic leukodystrophy H00423   Sphingolipidosis Drug target Atidarsagene autotemcel:  D12877<US> Cebsulfase alfa:  D12462 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     410 (ARSA)  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     410 (ARSA) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.6  Sulfuric-ester hydrolases     3.1.6.8  cerebroside-sulfatase      410 (ARSA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Sulfatase Sulfatase_C SGSH_C Phosphodiest DUF2477 DUF1501 Motif Other DBs NCBI-GeneID:  410 NCBI-ProteinID:  NP_000478 OMIM:  607574 HGNC:  713 Ensembl:  ENSG00000100299 UniProt:  P15289 A0A0C4DFZ2 B4DVI5 Structure PDBPDBj LinkDB All DBs Position 22:complement(50622754..50628152) Genome browser AA seq 509 aa AA seqDB search MSMGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLR FTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLT GMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVP IPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSF AERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLL RCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDL SPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASS SLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVA RGEDPALQICCHPGCTPRPACCHCPDPHA NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgtccatgggggcaccgcggtccctcctcctggccctggctgctggcctggccgttgcc cgtccgcccaacatcgtgctgatctttgccgacgacctcggctatggggacctgggctgc tatgggcaccccagctctaccactcccaacctggaccagctggcggcgggagggctgcgg ttcacagacttctacgtgcctgtgtctctgtgcacaccctctagggccgccctcctgacc ggccggctcccggttcggatgggcatgtaccctggcgtcctggtgcccagctcccggggg ggcctgcccctggaggaggtgaccgtggccgaagtcctggctgcccgaggctacctcaca ggaatggccggcaagtggcaccttggggtggggcctgagggggccttcctgcccccccat cagggcttccatcgatttctaggcatcccgtactcccacgaccagggcccctgccagaac ctgacctgcttcccgccggccactccttgcgacggtggctgtgaccagggcctggtcccc atcccactgttggccaacctgtccgtggaggcgcagcccccctggctgcccggactagag gcccgctacatggctttcgcccatgacctcatggccgacgcccagcgccaggatcgcccc ttcttcctgtactatgcctctcaccacacccactaccctcagttcagtgggcagagcttt gcagagcgttcaggccgcgggccatttggggactccctgatggagctggatgcagctgtg gggaccctgatgacagccataggggacctggggctgcttgaagagacgctggtcatcttc actgcagacaatggacctgagaccatgcgtatgtcccgaggcggctgctccggtctcttg cggtgtggaaagggaacgacctacgagggcggtgtccgagagcctgccttggccttctgg ccaggtcatatcgctcccggcgtgacccacgagctggccagctccctggacctgctgcct accctggcagccctggctggggccccactgcccaatgtcaccttggatggctttgacctc agccccctgctgctgggcacaggcaagagccctcggcagtctctcttcttctacccgtcc tacccagacgaggtccgtggggtttttgctgtgcggactggaaagtacaaggctcacttc ttcacccagggctctgcccacagtgataccactgcagaccctgcctgccacgcctccagc tctctgactgctcatgagcccccgctgctctatgacctgtccaaggaccctggtgagaac tacaacctgctggggggtgtggccggggccaccccagaggtgctgcaagccctgaaacag cttcagctgctcaaggcccagttagacgcagctgtgaccttcggccccagccaggtggcc cggggcgaggaccccgccctgcagatctgctgtcatcctggctgcaccccccgcccagct tgctgccattgcccagatccccatgcctga

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