Homo sapiens (human): 411 Help Entry 411               CDS       T01001                                  Symbol ARSB, ASB, G4S, MPS6 Name (RefSeq) arylsulfatase B   KO K01135   arylsulfatase B [EC:3.1.6.12] Organism hsa  Homo sapiens (human) Pathway hsa00531   Glycosaminoglycan degradation hsa01100   Metabolic pathways hsa04142   Lysosome Module hsa_M00076   Dermatan sulfate degradation hsa_M00077   Chondroitin sulfate degradation Network nt06012  Glycosaminoglycan degradation   Element N00610   Dermatan sulfate degradation Disease H00131   Mucopolysaccharidosis type VI H00421   Mucopolysaccharidosis Drug target Galsulfase:  D06565<JP/US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09107 Glycan biosynthesis and metabolism    00531 Glycosaminoglycan degradation     411 (ARSB)  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     411 (ARSB) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.6  Sulfuric-ester hydrolases     3.1.6.12  N-acetylgalactosamine-4-sulfatase      411 (ARSB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Sulfatase Phosphodiest Sulfatase_C Motif Other DBs NCBI-GeneID:  411 NCBI-ProteinID:  NP_000037 OMIM:  611542 HGNC:  714 Ensembl:  ENSG00000113273 UniProt:  P15848 Structure PDBPDBj LinkDB All DBs Position 5:complement(78777209..78985958) Genome browser AA seq 533 aa AA seqDB search MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD PEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt atgggtccgcgcggcgcggcgagcttgccccgaggccccggacctcggcggctgctcctc cccgtcgtcctcccgctgctgctgctgctgttgttggcgccgccgggctcgggcgccggg gccagccggccgccccacctggtcttcttgctggcagacgacctaggctggaacgacgtc ggcttccacggctcccgcatccgcacgccgcacctggacgcgctggcggccggcggggtg ctcctggacaactactacacgcagccgctgtgcacgccgtcgcggagccagctgctcact ggccgctaccagatccgtacaggtttacagcaccaaataatctggccctgtcagcccagc tgtgttcctctggatgaaaaactcctgccccagctcctaaaagaagcaggttatactacc catatggtcggaaaatggcacctgggaatgtaccggaaagaatgccttccaacccgccga ggatttgatacctactttggatatctcctgggtagtgaagattattattcccatgaacgc tgtacattaattgacgctctgaatgtcacacgatgtgctcttgattttcgagatggcgaa gaagttgcaacaggatataaaaatatgtattcaacaaacatattcaccaaaagggctata gccctcataactaaccatccaccagagaagcctctgtttctctaccttgctctccagtct gtgcatgagccccttcaggtccctgaggaatacttgaagccatatgactttatccaagac aagaacaggcatcactatgcaggaatggtgtcccttatggatgaagcagtaggaaatgtc actgcagctttaaaaagcagtgggctctggaacaacacggtgttcatcttttctacagat aacggagggcagactttggcagggggtaataactggccccttcgaggaagaaaatggagc ctgtgggaaggaggcgtccgaggggtgggctttgtggcaagccccttgctgaagcagaag ggcgtgaagaaccgggagctcatccacatctctgactggctgccaacactcgtgaagctg gccaggggacacaccaatggcacaaagcctctggatggcttcgacgtgtggaaaaccatc agtgaaggaagcccatcccccagaattgagctgctgcataatattgacccgaacttcgtg gactcttcaccgtgtcccaggaacagcatggctccagcaaaggatgactcttctcttcca gaatattcagcctttaacacatctgtccatgctgcaattagacatggaaattggaaactc ctcacgggctacccaggctgtggttactggttccctccaccgtctcaatacaatgtttct gagataccctcatcagacccaccaaccaagaccctctggctctttgatattgatcgggac cctgaagaaagacatgacctgtccagagaatatcctcacatcgtcacaaagctcctgtcc cgcctacagttctaccataaacactcagtccccgtgtacttccctgcacaggacccccgc tgtgatcccaaggccactggggtgtggggcccttggatgtag

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