Homo sapiens (human): 412 Help Entry 412               CDS       T01001                                  Symbol STS, ARSC, ARSC1, ASC, ES, SSDD, XLI Name (RefSeq) steroid sulfatase   KO K01131   steryl-sulfatase [EC:3.1.6.2] Organism hsa  Homo sapiens (human) Pathway hsa00140   Steroid hormone biosynthesis hsa01100   Metabolic pathways Disease H00134   X-linked ichthyosis Drug target Irosustat:  D09915 Brite Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.6  Sulfuric-ester hydrolases     3.1.6.2  steryl-sulfatase      412 (STS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Sulfatase Sulfatase_C SGSH_C Phosphodiest NAD_binding_8 Motif Other DBs NCBI-GeneID:  412 NCBI-ProteinID:  NP_000342 OMIM:  300747 HGNC:  11425 Ensembl:  ENSG00000101846 UniProt:  P08842 Structure PDBPDBj LinkDB All DBs Position X:7147290..7354641 Genome browser AA seq 578 aa AA seqDB search MKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKL TQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQ GYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRL VFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMM RNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQH GVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYK GGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRD LMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNGCFATH VCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVP DQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR NT seq 1737 nt NT seq  +upstreamnt  +downstreamnt atgaagatccctttcctcctactgttctttctgtgggaagccgagagccacgcagcatca aggccgaacatcatcctggtgatggctgacgacctcggcattggagatcctgggtgctat gggaacaaaactatcaggactcccaatatcgaccggttggccagtgggggagtgaaactc actcagcacctggcagcatcaccgctgtgcacaccaagcagggcagccttcatgactggc cggtaccctgtccgatcaggaatggcatcttggtcccgcactggagttttcctcttcaca gcctcttcgggaggacttcccaccgatgagattacctttgctaagcttctgaaggatcaa ggttattcaacagcactgatagggaaatggcaccttgggatgagctgtcacagcaagact gacttctgtcaccaccctttacatcacggcttcaattatttctatgggatctctttgacc aatctgagagactgcaagcccggagagggcagtgtcttcaccacgggcttcaagaggctg gtcttcctccccctgcagatcgtcggggtcaccctccttacccttgctgcactcaattgt ctggggctactccacgtgcctctaggcgtttttttcagccttctcttcctagcagcccta atcctgacccttttcttgggcttccttcattacttccggcccctgaactgcttcatgatg aggaactacgagatcattcagcagcccatgtcctatgacaatctcacccagaggctaacg gtggaggcggcccagttcatacagcggaacactgagactccgttcctgcttgtcttgtcc tacctccacgtgcacacagccctgttctccagcaaagactttgctggcaaaagtcaacac ggagtctacggggatgctgttgaggaaatggactggagtgtggggcagatcttgaacctt ctggatgagctgagattggctaatgataccctcatctacttcacatcggaccagggagca catgtagaagaagtgtcttccaaaggagaaattcatggcggaagtaatgggatctataaa ggaggaaaagcaaacaactgggaaggaggtatccgggttccaggcatccttcgttggccc agggtgatacaggctggccagaagattgatgagcccactagcaacatggacatatttcct acagtagccaagctggctggagctcccttgcctgaggacaggatcattgatggacgtgat ctgatgcccctgcttgaaggaaaaagccaacgctccgatcatgagtttctcttccattac tgcaacgcctacttaaatgctgtgcgctggcaccctcagaacagcacatccatctggaag gcctttttcttcacccccaacttcaaccccgtgggttccaacggatgctttgccacacac gtgtgcttctgtttcgggagttatgtcacccatcacgacccacctttactctttgatatt tccaaagatcccagagagagaaacccactaactccagcatccgagccccggttttatgaa atcctcaaagtcatgcaggaagctgcggacagacacacccagaccctgccagaggtgccc gatcagttttcatggaacaactttctttggaagccctggcttcagctgtgctgtccttcc accggcctgtcttgccagtgtgatagagaaaaacaggataagagactgagccgctag

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