| Entry |
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| Symbol |
MAP3K9, MEKK9, MLK1, PRKE1
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| Name |
(RefSeq) mitogen-activated protein kinase kinase kinase 9
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| KO |
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| Organism |
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| Pathway |
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| Network |
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| Element |
| N01594 | MLK-JNK signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
4293 (MAP3K9)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
4293 (MAP3K9)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: TKL group
MLK family
4293 (MAP3K9)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
14:complement(70722526..70809513)
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| AA seq |
1104 aa
MEPSRALLGCLASAAAAAPPGEDGAGAGAEEEEEEEEEAAAAVGPGELGCDAPLPYWTAV
FEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSR
CQPGGEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDED
ISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPD
ILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLARE
WHRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYG
VAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEESGFFEMPKDSFH
CLQDNWKHEIQEMFDQLRAKEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDIL
ERELNIIIHQLCQEKPRVKKRKGKFRKSRLKLKDGNRISLPSDFQHKFTVQASPTMDKRK
SLINSRSSPPASPTIIPRLRAIQLTPGESSKTWGRSSVVPKEEGEEEEKRAPKKKGRTWG
PGTLGQKELASGDEGSPQRREKANGLSTPSESPHFHLGLKSLVDGYKQWSSSAPNLVKGP
RSSPALPGFTSLMEMEDEDSEGPGSGESRLQHSPSQSYLCIPFPRGEDGDGPSSDGIHEE
PTPVNSATSTPQLTPTNSLKRGGAHHRRCEVALLGCGAVLAATGLGFDLLEAGKCQLLPL
EEPEPPAREEKKRREGLFQRSSRPRRSTSPPSRKLFKKEEPMLLLGDPSASLTLLSLSSI
SECNSTRSLLRSDSDEIVVYEMPVSPVEAPPLSPCTHNPLVNVRVERFKRDPNQSLTPTH
VTLTTPSQPSSHRRTPSDGALKPETLLASRSPSSNGLSPSPGAGMLKTPSPSRDPGEFPR
LPDPNVVFPPTPRRWNTQQDSTLERPKTLEFLPRPRPSANRQRLDPWWFVSPSHARSTSP
ANSSSTETPSNLDSCFASSSSTVEERPGLPALLPFQAGPLPPTERTLLDLDAEGQSQDST
VPLCRAELNTHRPAPYEIQQEFWS |
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| NT seq |
3315 nt +upstreamnt +downstreamnt
atggagccctccagagcgcttctcggctgcctagcgagcgccgccgctgccgccccgccg
ggggaggatggagcaggggccggggccgaggaggaggaggaggaggaggaggaggcggcg
gcggcggtgggccccggggagctgggctgcgacgcgccgctgccctactggacggccgtg
ttcgagtacgaggcggcgggcgaggacgagctgaccctgcggctgggcgacgtggtggag
gtgctgtccaaggactcgcaggtgtccggcgacgagggctggtggaccgggcagctgaac
cagcgggtgggcatcttccccagcaactacgtgaccccgcgcagcgccttctccagccgc
tgccagcccggcggcgaggaccccagttgctacccgcccattcagttgttagaaattgat
tttgcggagctcaccttggaagagattattggcatcgggggctttgggaaggtctatcgt
gctttctggataggggatgaggttgctgtgaaagcagctcgccacgaccctgatgaggac
atcagccagaccatagagaatgttcgccaagaggccaagctcttcgccatgctgaagcac
cccaacatcattgccctaagaggggtatgtctgaaggagcccaacctctgcttggtcatg
gagtttgctcgtggaggacctttgaatagagtgttatctgggaaaaggattcccccagac
atcctggtgaattgggctgtgcagattgccagagggatgaactacttacatgatgaggca
attgttcccatcatccaccgcgaccttaagtccagcaacatattgatcctccagaaggtg
gagaatggagacctgagcaacaagattctgaagatcactgattttggcctggctcgggaa
tggcaccgaaccaccaagatgagtgcggcagggacgtatgcttggatggcacccgaagtc
atccgggcctccatgttttccaaaggcagtgatgtgtggagctatggggtgctactttgg
gagttgctgactggtgaggtgccctttcgaggcattgatggcttagcagtcgcttatgga
gtggccatgaacaaactcgcccttcctattccttctacgtgcccagaaccttttgccaaa
ctcatggaagactgctggaatcctgatccccactcacgaccatctttcacgaatatcctg
gaccagctaaccaccatagaggagtctggtttctttgaaatgcccaaggactccttccac
tgcctgcaggacaactggaaacacgagattcaggagatgtttgaccaactcagggccaaa
gaaaaggaacttcgcacctgggaggaggagctgacgcgggctgcactgcagcagaagaac
caggaggaactgctgcggcgtcgggagcaggagctggccgagcgggagattgacatcctg
gaacgggagctcaacatcatcatccaccagctgtgccaggagaagccccgggtgaagaaa
cgcaagggcaagttcaggaagagccggctgaagctcaaggatggcaaccgcatcagcctc
ccttctgatttccagcacaagttcacggtgcaggcctcccctaccatggataaaaggaag
agtcttatcaacagccgctccagtcctcctgcaagccccaccatcattcctcgccttcga
gccatccagttgacaccaggtgaaagcagcaaaacctggggcaggagctcagtcgtccca
aaggaggaaggggaggaggaggagaagagggccccaaagaagaagggacggacgtggggg
ccagggacgcttggtcagaaggagcttgcctcgggagatgaaggatcccctcagagacgt
gagaaagctaatggtttaagtaccccatcagaatctccacatttccacttgggcctcaag
tccctggtagatggatataagcagtggtcgtccagtgcccccaacctggtgaagggccca
aggagtagcccggccctgccagggttcaccagccttatggagatggaggatgaggacagt
gaaggcccagggagtggagagagtcgcctacagcattcacccagccagtcctacctctgt
atcccattccctcgtggagaggatggcgatggcccctccagtgatggaatccatgaggag
cccaccccagtcaactcggccacgagtacccctcagctgacgccaaccaacagcctcaag
cggggcggtgcccaccaccgccgctgcgaggtggctctgctcggctgtggggctgttctg
gcagccacaggcctagggtttgacttgctggaagctggcaagtgccagctgcttcccctg
gaggagcctgagccaccagcccgggaggagaagaaaagacgggagggtctttttcagagg
tccagccgtcctcgtcggagcaccagccccccatcccgaaagcttttcaagaaggaggag
cccatgctgttgctaggagacccctctgcctccctgacgctgctctccctctcctccatc
tccgagtgcaactccacacgctccctgctgcgctccgacagcgatgaaattgtcgtgtat
gagatgccagtcagcccagtcgaggcccctcccctgagtccatgtacccacaaccccctg
gtcaatgtccgagtagagcgcttcaaacgagatcctaaccaatctctgactcccacccat
gtcaccctcaccaccccctcgcagcccagcagtcaccggcggactccttctgatggggcc
cttaagccagagactctcctagccagcaggagcccctccagcaatgggttgagccccagt
cctggagcaggaatgttgaaaacccccagtcccagccgagacccaggtgaattcccccgt
ctccctgaccccaatgtggtcttccccccaaccccaaggcgctggaacactcagcaggac
tctaccttggagagacccaagactctggagtttctgcctcggccgcgtccttctgccaac
cggcaacggctggacccttggtggtttgtgtcccccagccatgcccgcagcacctcccca
gccaacagctccagcacagagacgcccagcaacctggactcctgctttgctagcagtagc
agcactgtagaggagcggcctggacttccagccctgctcccgttccaggcagggccgctg
cccccgactgagcggacgctcctggacctggatgcagaggggcagagtcaggacagcacc
gtgccgctgtgcagagcggaactgaacacacacaggcctgccccttatgagatccagcag
gagttctggtcttag |
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