Homo sapiens (human): 4751 Help Entry 4751              CDS       T01001                                  Symbol NEK2, HsPK21, NEK2A, NLK1, PPP1R111, RP67 Name (RefSeq) NIMA related kinase 2   KO K20872   serine/threonine-protein kinase Nek2 [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Disease H00527   Retinitis pigmentosa Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     4751 (NEK2)    01009 Protein phosphatases and associated proteins [BR:hsa01009]     4751 (NEK2)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     4751 (NEK2) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      4751 (NEK2) Protein kinases [BR:hsa01001]  Serine/threonine kinases: Other   NEK family    4751 (NEK2) Protein phosphatases and associated proteins [BR:hsa01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      4751 (NEK2) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      4751 (NEK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 APH Motif Other DBs NCBI-GeneID:  4751 NCBI-ProteinID:  NP_002488 OMIM:  604043 HGNC:  7745 Ensembl:  ENSG00000117650 UniProt:  P51955 Structure PDBPDBj LinkDB All DBs Position 1:complement(211658256..211675621) Genome browser AA seq 445 aa AA seqDB search MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE RKFLSLASNPELLNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAA QLRAQALSDIEKNYQLKSRQILGMR NT seq 1338 nt NT seq  +upstreamnt  +downstreamnt atgccttcccgggctgaggactatgaagtgttgtacaccattggcacaggctcctacggc cgctgccagaagatccggaggaagagtgatggcaagatattagtttggaaagaacttgac tatggctccatgacagaagctgagaaacagatgcttgtttctgaagtgaatttgcttcgt gaactgaaacatccaaacatcgttcgttactatgatcggattattgaccggaccaataca acactgtacattgtaatggaatattgtgaaggaggggatctggctagtgtaattacaaag ggaaccaaggaaaggcaatacttagatgaagagtttgttcttcgagtgatgactcagttg actctggccctgaaggaatgccacagacgaagtgatggtggtcataccgtattgcatcgg gatctgaaaccagccaatgttttcctggatggcaagcaaaacgtcaagcttggagacttt gggctagctagaatattaaaccatgacacgagttttgcaaaaacatttgttggcacacct tattacatgtctcctgaacaaatgaatcgcatgtcctacaatgagaaatcagatatctgg tcattgggctgcttgctgtatgagttatgtgcattaatgcctccatttacagcttttagc cagaaagaactcgctgggaaaatcagagaaggcaaattcaggcgaattccataccgttac tctgatgaattgaatgaaattattacgaggatgttaaacttaaaggattaccatcgacct tctgttgaagaaattcttgagaaccctttaatagcagatttggttgcagacgagcaaaga agaaatcttgagagaagagggcgacaattaggagagccagaaaaatcgcaggattccagc cctgtattgagtgagctgaaactgaaggaaattcagttacaggagcgagagcgagctctc aaagcaagagaagaaagattggagcagaaagaacaggagctttgtgttcgtgagagacta gcagaggacaaactggctagagcagaaaatctgttgaagaactacagcttgctaaaggaa cggaagttcctgtctctggcaagtaatccagaacttcttaatcttccatcctcagtaatt aagaagaaagttcatttcagtggggaaagtaaagagaacatcatgaggagtgagaattct gagagtcagctcacatctaagtccaagtgcaaggacctgaagaaaaggcttcacgctgcc cagctgcgggctcaagccctgtcagatattgagaaaaattaccaactgaaaagcagacag atcctgggcatgcgctag

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