| Entry |
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| Symbol |
SGSH, HSS, MPS3A, SFMD
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| Name |
(RefSeq) N-sulfoglucosamine sulfohydrolase
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| KO |
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| Organism |
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| Pathway |
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| Module |
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| Network |
nt06012 Glycosaminoglycan degradation |
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| Element |
| N00615 | Heparan sulfate degradation |
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| Disease |
| H00130 | Mucopolysaccharidosis type III |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
6448 (SGSH)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
6448 (SGSH)
Enzymes [BR:hsa01000]
3. Hydrolases
3.10 Acting on sulfur-nitrogen bonds
3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
3.10.1.1 N-sulfoglucosamine sulfohydrolase
6448 (SGSH)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
17:complement(80200673..80220333)
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| AA seq |
502 aa
MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLF
RNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGI
IGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDP
HRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQY
TTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPE
HPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWAT
VFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQP
TGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWV
CAPDGVLEEKLSPQCQPLHNEL |
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| NT seq |
1509 nt +upstreamnt +downstreamnt
atgagctgccccgtgcccgcctgctgcgcgctgctgctagtcctggggctctgccgggcg
cgtccccggaacgcactgctgctcctcgcggatgacggaggctttgagagtggcgcgtac
aacaacagcgccatcgccaccccgcacctggacgccttggcccgccgcagcctcctcttt
cgcaatgccttcacctcggtcagcagctgctctcccagccgcgccagcctcctcactggc
ctgccccagcatcagaatgggatgtacgggctgcaccaggacgtgcaccacttcaactcc
ttcgacaaggtgcggagcctgccgctgctgctcagccaagctggtgtgcgcacaggcatc
atcgggaagaagcacgtggggccggagaccgtgtacccgtttgactttgcgtacacggag
gagaatggctccgtcctccaggtggggcggaacatcactagaattaagctgctcgtccgg
aaattcctgcagactcaggatgaccggcctttcttcctctacgtcgccttccacgacccc
caccgctgtgggcactcccagccccagtacggaaccttctgtgagaagtttggcaacgga
gagagcggcatgggtcgtatcccagactggaccccccaggcctacgacccactggacgtg
ctggtgccttacttcgtccccaacaccccggcagcccgagccgacctggccgctcagtac
accaccgtcggccgcatggaccaaggagttggactggtgctccaggagctgcgtgacgcc
ggtgtcctgaacgacacactggtgatcttcacgtccgacaacgggatccccttccccagc
ggcaggaccaacctgtactggccgggcactgctgaacccttactggtgtcatccccggag
cacccaaaacgctggggccaagtcagcgaggcctacgtgagcctcctagacctcacgccc
accatcttggattggttctcgatcccgtaccccagctacgccatctttggctcgaagacc
atccacctcactggccggtccctcctgccggcgctggaggccgagcccctctgggccacc
gtctttggcagccagagccaccacgaggtcaccatgtcctaccccatgcgctccgtgcag
caccggcacttccgcctcgtgcacaacctcaacttcaagatgccctttcccatcgaccag
gacttctacgtctcacccaccttccaggacctcctgaaccgcaccacagctggtcagccc
acgggctggtacaaggacctccgtcattactactaccgggcgcgctgggagctctacgac
cggagccgggacccccacgagacccagaacctggccaccgacccgcgctttgctcagctt
ctggagatgcttcgggaccagctggccaagtggcagtgggagacccacgacccctgggtg
tgcgcccccgacggcgtcctggaggagaagctctctccccagtgccagcccctccacaat
gagctgtga |
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