| Entry |
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| Symbol |
WNK3, MRXS2, PRKWNK3, PRS
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| Name |
(RefSeq) WNK lysine deficient protein kinase 3
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| KO |
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| Organism |
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| Pathway |
| hsa04928 | Parathyroid hormone synthesis, secretion and action |
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| Disease |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
65267 (WNK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
65267 (WNK3)
01009 Protein phosphatases and associated proteins [BR:hsa01009]
65267 (WNK3)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
65267 (WNK3)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: Other
Wnk family
65267 (WNK3)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
65267 (WNK3)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
X:complement(54192823..54358900)
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| AA seq |
1800 aa
MATDSGDPASTEDSEKPDGISFENRVPQVAATLTVEARLKEKNSTFSASGETVERKRFFR
KSVEMTEDDKVAESSPKDERIKAAMNIPRVDKLPSNVLRGGQEVKYEQCSKSTSEISKDC
FKEKNEKEMEEEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQD
RKLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLK
RFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL
MRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRK
VTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVELAEEDD
CSNSSLALRLWVEDPKKLKGKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAV
AKSIRDRVTPIKKTREKKPAGCLEERRDSQCKSMGNVFPQPQNTTLPLAPAQQTGAECEE
TEVDQHVRQQLLQRKPQQHCSSVTGDNLSEAGAASVIHSDTSSQPSVAYSSNQTMGSQMV
SNIPQAEVNVPGQIYSSQQLVGHYQQVSGLQKHSKLTQPQILPLVQGQSTVLPVHVLGPT
VVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKPDLVRSLNQDVATTKENVSSPDNPS
GNGKQDRIKQRRASCPRPEKGTKFQLTVLQVSTSGDNMVECQLETHNNKMVTFKFDVDGD
APEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQEILHVHFATERATGVDSITVDSNSS
QTGSSEQVQINSTSTQTSNESAPQSSPVGRWRFCINQTIRNRETQSPPSLQHSMSAVPGR
HPLPSPKNTSNKEISRDTLLTIENNPCHRALFTSKSEHKDVVDGKISECASVETKQPAIL
YQVEDNRQIMAPVTNSSSYSTTSVRAVPAECEGLTKQASIFIPVYPCHQTASQADALMSH
PGESTQTSGNSLTTLAFDQKPQTLSVQQPAMDAEFISQEGETTVNTEASSPKTVIPTQTP
GLEPTTLQPTTVLESDGERPPKLEFADNRIKTLDEKLRNLLYQEHSISSIYPESQKDTQS
IDSPFSSSAEDTLSCPVTEVIAISHCGIKDSPVQSPNFQQTGSKLLSNVAASQPANISVF
KRDLNVITSVPSELCLHEMSSDASLPGDPEAYPAAVSSGGAIHLQTGGGYFGLSFTCPSL
KNPISKKSWTRKLKSWAYRLRQSTSFFKRSKVRQVETEEMRSAIAPDPIPLTRESTADTR
ALNRCKAMSGSFQRGRFQVITIPQQQSAKMTSFGIEHISVFSETNHSSEEAFIKTAKSQL
VEIEPATQNPKTSFSYEKLQALQETCKENKGVPKQGDNFLSFSAACETDVSSVTPEKEFE
ETSATGSSMQSGSELLLKEREILTAGKQPSSDSEFSASLAGSGKSVAKTGPESNQCLPHH
EEQAYAQTQSSLFYSPSSPMSSDDESEIEDEDLKVELQRLREKHIQEVVNLQTQQNKELQ
ELYERLRSIKDSKTQSTEIPLPPASPRRPRSFKSKLRSRPQSLTHVDNGIVATGKSCLIN
ELENPLCVESNAASCQQSPASKKGMFTDDLHKLVDDWTKEAVGNSLIKPSLNQLKQSQHK
LETENWNKVSENTPSTMGYTSTWISSLSQIRGAVPTSLPQGLSLPSFPGPLSSYGMPHVC
QYNAVAGAGYPVQWVGISGTTQQSVVIPAQSGGPFQPGMNMQAFPTSSVQNPATIPPGPK |
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| NT seq |
5403 nt +upstreamnt +downstreamnt
atggccactgattcaggggatccagccagcacagaagattctgagaaacctgatggaatt
tcatttgaaaacagagttccccaggtcgctgcaactttgacagtagaagctagactaaag
gagaaaaacagtaccttctctgcttctggggaaactgtagaaaggaagagatttttccga
aagagtgttgaaatgacggaagatgacaaagttgccgaatcatcccccaaagatgagaga
attaaggctgcaatgaatattccaagagtagataagcttccttcaaatgtgttgagaggt
ggacaagaagttaaatatgaacagtgttcaaagtcaacctcagaaatctcaaaagattgt
ttcaaggagaaaaatgaaaaggaaatggaagaagaagcagaaatgaaggctgtagctact
tctcctagtggcagattcctgaaatttgacatagaactaggaagaggagcatttaaaaca
gtatataaaggactggacactgaaacatgggttgaggttgcttggtgtgagctgcaggac
cgaaagttaaccaaagctgagcagcaaagattcaaggaagaagcagagatgttgaagggt
ctccagcaccccaatatagttcgattttatgattcctgggaatctatattaaaaggaaag
aaatgtattgtattagtgactgaactaatgacatctgggaccttaaagacgtacttaaaa
cgatttaaagtcatgaaaccaaaggtcttaaggagctggtgcaggcaaattttaaagggg
ttgcagttcttgcacactaggactcctcctattattcaccgggatctgaagtgtgacaat
attttcatcacgggacccactggatctgtgaagattggtgatctaggattagccacctta
atgcgtacctcatttgctaagagtgtcattggaactcctgagtttatggctccagagatg
tatgaagaacactatgatgaatccgtagatgtttatgcttttggaatgtgtatgctggaa
atggccacatcggagtatccttattctgagtgtcagaatgcagctcaaatataccggaaa
gtaactagtggcataaaaccagccagcttcaataaagtcactgatcctgaagtcaaagaa
atcattgaaggatgtattcgtcaaaacaaatctgaaaggttgtctatcagggacctatta
aaccatgcattttttgctgaggatacaggactgagggtggagttagcagaagaagatgat
tgctcaaattcatcccttgctttaagactctgggttgaagaccctaaaaaattgaaaggc
aaacacaaagacaatgaagctattgaatttagtttcaacttagaaacagatacacctgag
gaagtagcatatgaaatggtcaagtctgggttcttccatgaaagtgattccaaagctgtt
gctaaatccattagagaccgggtgacgccaataaagaagacaagagagaagaagcctgct
ggctgtttggaagaacgcagggattctcagtgcaagtctatggggaatgtattccctcag
ccccagaatacaactttaccccttgctcccgctcagcaaactggggctgaatgtgaagaa
actgaagttgatcaacatgttagacaacagcttctacaaagaaaaccacagcagcactgc
tcctctgttacaggtgacaatttgtctgaggcaggagctgcatcagttatacattcagat
acttcaagtcagcccagtgtagcctattcctcaaatcaaacgatgggctctcaaatggtt
tctaatatcccgcaggctgaagtaaatgttccagggcaaatttattcatctcagcaacta
gtaggacattaccagcaagtttcagggttacagaagcattcaaagctgactcagccgcag
attttgcctttggttcaaggtcagtccactgttttacctgtacatgtccttggaccgaca
gttgtttcacaaccccaggtttccccattaactgttcagaaggtcccacagataaagcct
gtatcccaaccagttggagctgaacaacaagcagctcttctaaaaccagatttagttcga
agcttgaatcaagatgtggcaactacgaaggaaaacgtcagtagccctgataacccaagt
ggaaatggcaaacaggatcggatcaaacagagaagagcttcctgtccccgaccagagaag
gggactaaatttcagcttaccgtccttcaggtatcaacctctggagataacatggtagag
tgtcagctggagacacacaacaacaagatggtcaccttcaagtttgatgttgatggtgat
gcgccagaggatattgcagactatatggttgaagataactttgtgctggaaagtgagaaa
gaaaaatttgtagaagaattgagagctattgtaggtcaagcccaggagatccttcatgtc
cactttgccacagaaagagccactggagttgattctattactgtggactccaacagtagc
cagacagggtcatctgaacaagtacagataaattctacatctactcaaaccagcaatgaa
tctgctcctcagtcatccccagttggtcggtggcgattctgtatcaatcagacgataaga
aaccgtgagactcagtctcctccttctcttcagcattccatgtctgcggttcctggccga
catccacttcctagtccaaaaaacacaagtaataaggaaatatcacgggacacattgctc
actatagaaaataatccatgccaccgtgcacttttcacctccaaatcagaacacaaggat
gtggttgatggtaagatttctgaatgtgctagtgtagaaaccaagcagccagctatactt
tatcaagtggaagataacaggcagataatggcaccagttactaatagttccagttactct
actacttcagttcgtgcagttccagctgaatgtgagggactcaccaaacaagcaagcata
ttcatacctgtgtatccatgtcaccaaactgccagtcaggctgatgcacttatgtcccat
cctggcgaatcaactcagacttctggtaactctcttacaactctggcatttgatcaaaag
cctcaaaccttatcagtacagcagccagctatggatgcagagtttatttctcaagaagga
gaaactacagtgaacactgaagcaagttctcctaagacagtcattcccactcagacccct
ggccttgaaccaactacccttcaacccactactgtcctggaatcagatggagaaagacct
ccaaaactggagtttgcagacaaccgaattaaaactctggatgaaaaattaagaaacttg
ctctatcaggagcacagcatctctagcatctatcccgagagtcagaaggatacccaaagc
atagactctccattttcttcctctgctgaagataccctctcctgtccagtgacagaagtc
atagccatcagtcactgtggaattaaagatagccctgtacaatcccctaatttccaacag
acaggctctaagcttctgtccaatgtggctgcaagtcagcctgctaatatatcagtgttc
aaaagggacctgaatgtgataacttctgtacccagcgaattgtgtttacatgagatgtcc
tcagatgcttcacttccaggggatccagaggcctatcctgctgctgtgtcaagcggtgga
gccattcatctgcagacaggaggtggatattttggcctaagctttacttgtcctagtctc
aaaaatcctattagcaagaaatcctggactcgcaaattaaaaagctgggcatacaggcta
cggcagtcaaccagctttttcaagagatcaaaagtccgtcaagtggaaacagaagagatg
agatcagcaattgctcctgatcccattcctctgacacgggagtccacagctgatactagg
gctttgaatagatgtaaagcgatgagtggatcatttcagcggggtcggttccaggtgatt
acaattcctcagcagcagtcagcaaaaatgacatcttttggaatagaacacatatcagtg
ttcagtgagacaaaccattctagtgaagaagcctttattaaaacagcaaagtctcagttg
gtagaaatagaacctgccacacaaaatccaaaaacttcgttttcttatgagaagttacaa
gctcttcaggaaacctgtaaagaaaataaaggagttcccaaacaaggtgacaacttctta
tctttcagcgcagcttgtgagactgatgtatcttcagtgaccccagaaaaggaatttgaa
gaaacttcagccacaggaagtagcatgcagtctggatctgaactgttgcttaaagagaga
gagatattgactgctgggaaacagcctagctctgatagtgaattttcagccagtcttgct
ggcagtggaaagtcagtggcaaagactggtccagagagtaatcagtgcttaccacaccac
gaagaacaagcttatgctcaaacacagagttcactcttctattcgccatcttccccaatg
agcagtgatgatgaatcagaaatagaggatgaggacttgaaggtggagcttcaaagatta
cgagaaaaacacattcaggaggtggtaaatcttcaaacccagcagaataaggagctgcag
gagctctatgaacgccttcggtcaattaaagatagcaaaacccaatctactgagattcct
ttgccacctgcatcaccacgtcgaccaagatctttcaaaagcaaacttcgaagccgcccc
cagtccttgacacatgtggacaatggcatagttgctacagggaaaagctgccttataaat
gagttggaaaatccactgtgtgtggagagtaatgcagcatcatgccaacagtctccagcc
agtaaaaaagggatgttcacagatgacttacacaagctggtggatgactggacaaaggaa
gcagtaggaaattctcttattaagccaagtttaaaccaacttaaacaaagtcaacacaaa
ctagagacagaaaactggaataaagtatctgaaaatactccgtctactatgggctacaca
tcaacatggatttcttctctgtcccaaatccgtggagctgtcccaacttccttgccacaa
ggactctcactcccttcatttcctgggccattatcatcatatggaatgcctcacgtttgt
cagtataatgctgtggcgggggcggggtatccagtacagtgggtaggaatttcaggaaca
acacaacaatctgtagtaattcccgcccaatctgggggaccattccagccagggatgaat
atgcaggcatttccaacttcatcagtgcagaatcctgccacaatccctcctggtcctaaa
tga |
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