| Entry |
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| Symbol |
WNK2, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43
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| Name |
(RefSeq) WNK lysine deficient protein kinase 2
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| KO |
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| Organism |
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| Pathway |
| hsa04928 | Parathyroid hormone synthesis, secretion and action |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
65268 (WNK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
65268 (WNK2)
01009 Protein phosphatases and associated proteins [BR:hsa01009]
65268 (WNK2)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
65268 (WNK2)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: Other
Wnk family
65268 (WNK2)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
65268 (WNK2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
9:93184139..93320569
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| AA seq |
2297 aa
MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA
EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG
TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE
DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK
EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS
WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT
PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK
VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV
EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ
WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP
PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP
VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG
PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM
PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL
PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH
SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP
TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG
SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV
QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG
SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK
MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM
LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE
HPAPEAPESSPPLPLSSLPPEASQGPCRGLTLPCLPWRRAACGAVFLSLFSAESAQSKQP
PDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPAT
STMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAA
STRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTV
PPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDF
TLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSS
MTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEP
PPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPH
SLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQ
ASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSD
NDSELEDADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPT
GRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTADSTGL
SGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGWTVYHPTSERVTYKSSSKPRARFL
SGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTD
DLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMP
RLPPAPGPLSTTVIPGAAPTLSVPTPDGALGTARRNQVWFGLRVPPTACCGHSTQPRGGQ
RVGSKTASFAASDPVRS |
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| NT seq |
6894 nt +upstreamnt +downstreamnt
atggacggcgatggcggccgccgagacgtccccggcacgctgatggagcccgggcgcggc
gcggggcccgcgggcatggcggagcctcgggcgaaggcggcgcggccggggccccagcgc
tttctgcggcgcagcgtggtagagtcggaccaggaggagccgccgggcttggaggcagcc
gaggcgccgggcccgcagcccccgcagcccctgcagcgccgggtgcttctgctctgcaag
acgcgccgcctcatcgcggagcgcgcccgcggacgccccgccgcccccgcgcccgcagcg
ctggtagcgcagccgggagcccccggagcccccgcggacgccggccccgagcccgtgggc
acgcaggagcccggcccggaccccatcgcagccgctgtcgaaaccgcgcctgcccccgac
ggcggccccagggaggaggcggcggcgaccgtgaggaaggaggatgagggggcggccgag
gcgaagcctgagcccgggcgcactcgccgggacgagcccgaagaggaggaggacgacgag
gacgacctcaaggccgtggccacctctctggacggccgcttcctcaagttcgacatcgag
ctgggccgcggttccttcaagacggtctacaaggggctggacacggagacctgggtggag
gtggcctggtgtgagctgcaggaccggaagctcaccaagctggagcggcagcggttcaag
gaagaggctgagatgctgaaaggcctgcagcaccccaacatcgtgcgcttctacgacttc
tgggagtccagcgccaagggcaagcggtgcattgtgctggtgacggagctgatgacctca
gggacgctgaagacatacctgaagcggttcaaggtgatgaagcccaaggttctccgcagc
tggtgccggcagatcctgaagggcctgctgttcctgcacacaaggacgccacccatcatc
caccgagacctgaaatgtgacaatattttcatcaccggaccaactgggtctgtgaagatt
ggcgacttgggcctggccactctgaaaagagcgtcatttgccaaaagtgtgataggtact
cccgagttcatggcgcccgagatgtacgaggagcactacgatgagtccgtggacgtctat
gcctttgggatgtgcatgctggagatggccacctcggagtacccctactcggagtgccag
aatgcggcccagatctaccgcaaggtcacctgtggtatcaagccggccagctttgagaaa
gtgcacgatcctgaaatcaaggagattattggggagtgtatctgcaaaaacaaggaggaa
aggtacgagatcaaagacctgctgagccacgccttcttcgcagaggacacaggcgtgagg
gtggagctcgcggaggaggaccacggcaggaagtccaccatcgccctgaggctctgggtg
gaagaccccaagaaactgaagggaaagcccaaggacaatggagccatagagttcaccttc
gacctggagaaggagacgccggatgaggtggcccaagagatgattgagtctggattcttc
cacgagagtgacgtcaagatcgtggccaagtccatccgtgaccgcgtggccttgatccag
tggcggcgggagaggatctggcccgcgctgcagcccaaggagcagcaggatgtgggcagc
ccggacaaggccaggggtccgccggtgcccctgcaggtccaggtgacctaccatgcacag
gctgggcagcccgggccaccagagcccgaggagccggaggccgaccagcacctcctgcca
cctacgttgccgaccagcgccacctccctggcctcggacagcaccttcgacagcggccag
ggctctaccgtgtactcagactcgcagagcagccagcagagcgtgatgcttggctccctt
gccgacgcagcgccgtccccggcccagtgtgtgtgcagcccccctgtgagcgaggggccc
gtcctgccgcagagcctgccctcgctgggggcctaccagcagcccacggctgcacctggc
ttgccggtgggctctgtcccggcccccgcctgccctccgtccctccagcagcacttcccg
gatccggccatgagcttcgcccccgtgctgccgccgcccagcacccccatgcccacgggc
ccaggccagccagcaccccccggccagcagcctcctccgctggcccagccgacacccctg
ccgcaggtcctggccccacagcccgtggtccccctccagccggttcccccccacctgcca
ccgtacctggctccagcctcccaggtgggggcccccgctcagctgaagcccctccagatg
ccacaggcgcccctgcagccgcttgctcaagtccctccgcagatgcccccgattcctgtt
gtgccccccatcacgcccctggcgggaatcgacggcctccctccggccctcccagacctg
ccgaccgcgactgtgcctcccgtgccaccacctcagtatttctctccagccgtgatcttg
ccgagcctcgctgccccactcccccctgcgtccccagccttgcctctgcaggctgtgaag
ctgccccacccccctggggcgcccctggccatgccctgccggaccattgtgccaaatgca
ccggccactatccccctgctggccgtagccccaccgggcgtggctgccctgtccattcat
tctgccgtggcccagctcccaggccaacctgtgtacccagcggccttcccacagatggcg
cctactgacgtccctccttccccccatcacacggtgcagaatatgagggccacccctcca
cagccggcactgcctccacaacccacactgcccccacaacccgtgctgcccccgcaaccc
acgctgccccctcaacctgtgttgcccccgcaacccacacggccccctcaacctgtgctg
cccccgcaacccatgctgcccccacaacctgtgctgcccccgcagccggcactgcctgtg
cgccctgagcccctccagccccaccttcctgaacaagctgctccagctgctacaccaggg
agccagattctgcttggccacccagctccctatgctgtggacgtcgccgctcaggtcccc
accgtgcctgtgccaccggctgcggtcctctcgccgcctctgccggaagtgctgctgcct
gccgcccctgagctcctgcctcagttccccagctccctggccacggtgtctgcctctgtg
cagagtgtgcccacccagactgccacacttctgccaccagcaaacccaccgctgcctggc
gggcccgggatcgccagcccttgcccaactgtccagctgacggtggaaccagtccaagag
gagcaggcctcacaggacaagccgcccggcctcccgcagagctgtgagagctatggaggt
tctgatgtcacttctggaaaagagctgagtgacagctgtgaaggcgcctttggagggggc
aggctggagggcagggcagcccgaaaacaccaccgcaggtccacgcgtgcgcgctcccgg
caggagagggccagccggccccggcttaccatcttgaacgtgtgcaacactggggacaag
atggtggagtgccagctggagacgcacaaccacaagatggtgaccttcaagttcgacttg
gacggggacgcacccgatgaaattgccacgtatatggtggagcatgactttatcctgcag
gccgagcgggaaacgttcatcgagcagatgaaggatgtcatggacaaggcagaggacatg
ctcagcgaggacacagacgccgaccgtggctccgacccagggaccagcccgccacacctc
agcacctgcggcctgggcaccggggaggagagccgacaatcccaagccaacgcccccgtg
tatcagcagaacgtcctgcacaccgggaagaggtggttcatcatctgtccggtggctgag
caccccgcccccgaggcccctgaatcttcgcccccacttcctctaagctccctgccgcca
gaagccagccaaggtccatgcagggggctcaccctgccctgtctcccatggcgcagagca
gcctgtggggctgtgttcctatccttgttttctgctgaatcagctcagtcaaagcagcct
ccagattcagcgccctataaagaccagctgtcctcgaaggaacaacccagctttctagcc
agtcagcagctcctgagccaggcgggccccagcaaccctcctggggcacccccagcccct
ttggccccctcctcccctcctgtgactgctctgccccaagatggagcagctccagccacc
agcaccatgccagagccagcgtcaggaactgccagccaggcagggggtccagggacacct
caggggctgaccagtgagctcgagacgtctcagccactagcggagactcacgaggccccg
cttgctgtgcagcccctcgtggtgggcctagcaccttgcactccagctccagaggctgcc
tcaaccagggacgccagtgccccaagggagcccctgccacctcctgcacctgagcccagc
ccccacagcgggaccccacagcccgccttgggtcaacctgctcccctgcttcctgccgca
gtgggggccgtcagcctggccacctcccagctcccaagcccacccctggggcccaccgtc
cccccacagccaccctcggccctggagtcggatggggaagggccgccccccagggtgggc
tttgtggacagcaccatcaagagcctggacgagaagctgcggactctgctctaccaggag
cacgtgcccacctcctcagcctcagctgggacccctgtggaggtgggcgacagagacttc
accctggagcccctgagaggggaccagccccgctcagaggtctgcgggggggacctggcc
ctgcccccagtgcctaaggaggcggtctcagggcgtgtccagctgccccagcccttggtg
gagaagtcagaactggcccccactcgaggggccgtgatggagcagggcacgtcctcgtca
atgacagcagagtcgtctcccaggagtatgctaggctatgacagagatggaaggcaggtg
gcctcagactcccatgtggtccccagcgtcccccaggatgtacctgcttttgtgagacct
gcacgtgtggagcccacagacagggatggtggagaagctggagaaagctcggcagagccc
ccgccgagtgacatgggcacagtggggggccaggctagccacccccagacactcggcgct
cgagctttggggtcccctcggaaacgtccagagcagcaggatgtcagctcaccagccaag
actgtgggccgtttctcggtggtcagcactcaggacgagtggaccctggcctccccccac
agcctgagatactctgccccacccgacgtctacctggacgaggccccctccagccccgac
gtgaagctggcagtgcggcgggcgcagacggcctcctccatcgaggtcggcgtgggcgag
cccgtgtccagcgactctggggacgagggccctcgggcgagacccccggtgcagaagcag
gcgtccctgcccgtgagtggcagcgtggctggcgacttcgtgaagaaggccaccgccttc
ctgcagaggccttctcgggccggctcgctgggccccgagacacccagcagggtgggcatg
aaggtccccacgatcagcgtgacctccttccattcccagtcgtcctacatcagcagcgac
aatgattcggagctcgaggatgctgacataaagaaggagctgcagagtctgcgggagaag
cacctgaaggagatctcggagctgcagagccagcagaagcaggagatcgaagctctgtac
cgccgcctgggcaagccactgccccccaacgtgggcttcttccacacggcaccccccact
ggccgccggagaaaaaccagcaagagcaagctgaaggcaggcaagctgctaaatcccctg
gtgcggcagctcaaggtcgtggcctccagcacaggtcacttggctgactccagcagaggc
cctcccgctaaggaccctgcccaagccagtgtggggctcactgcagacagcacgggcctg
agcgggaaggcagtgcagacccagcagccctgctccgtccgggcctccctgtcttcggac
atctgctccggcttagccagtgatggaggcggagcgcgtggccaaggctggacggtttac
cacccaacgtctgagagagtgacctataagtctagtagcaaacctcgtgctcgattcctc
agtggacccgtatctgtgtccatctggtctgccctgaagcgtctctgcctaggcaaagaa
cacagcagtaggtcctccaccagcagcctggccccaggccctgagccaggcccccagccc
gccctgcacgtccaggcgcaggtgaacaacagcaacaacaagaagggtaccttcacggac
gacctgcacaagctggtggacgagtggacgagcaagacggtgggggccgcgcagctgaag
cccacgctcaaccagctgaagcagacccagaagctgcaagacatggaggcccaggcaggc
tgggctgcccctggcgaggcgcgggctatgaccgcacctcgagcaggagtggggatgcca
cgtctgcccccagcgcccggccctctgtccaccacggtcattcccggagccgccccgacc
ctgtccgtgcccacaccagatggcgccctcggaaccgcccggagaaaccaggtgtggttt
ggcctccgagtcccccccaccgcctgctgtgggcacagcactcagccgcgagggggacag
cgggtgggcagcaagactgcttcctttgcggcttcagaccctgttcgctcctag |
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