| Entry |
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| Symbol |
MAP3K12, DLK, HP09298, MEKK12, MUK, ZPK, ZPKP1
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| Name |
(RefSeq) mitogen-activated protein kinase kinase kinase 12
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| KO |
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| Organism |
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| Pathway |
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| Network |
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| Element |
| N01594 | MLK-JNK signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
7786 (MAP3K12)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
7786 (MAP3K12)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: TKL group
MLK family
7786 (MAP3K12)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
12:complement(53479669..53501539)
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| AA seq |
859 aa
MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTHVLQLHEQDAGGPGG
AAGSPESRASRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEV
PFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVC
TQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSP
NMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVL
WELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQI
LLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELR
HALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGL
LHGNTMEKLIKKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCPKGPPSPGRS
RRGKTRHRKASAKGSCGDLPGLRTAVPPHEPGGPGSPGGLGGGPSAWEACPPALRGLHHD
LLLRKMSSSSPDLLSAALGSRGRGATGGAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGG
AKGEPPPPVGPGEGVGLLGTGREGTSGRGGSRAGSQHLTPAALLYRAAVTRSQKRGISSE
EEEGEVDSEVELTSSQRWPQSLNMRQSLSTFSSENPSDGEEGTASEPSPSGTPEVGSTNT
DERPDERSDDMCSQGSEIPLDPPPSEVIPGPEPSSLPIPHQELLRERGPPNSEDSDCDST
ELDNSNSVDALRPPASLPP |
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| NT seq |
2580 nt +upstreamnt +downstreamnt
atggcttgcctccatgagacccgaacaccctctccttcctttgggggctttgtgtctacc
ctaagtgaggcatccatgcgcaagctggacccagacacttctgactgcactcccgagaag
gacctgacgcctacccatgtcctgcagctacatgagcaggatgcagggggcccaggggga
gcagctgggtcacctgagagtcgggcatccagagttcgagctgacgaggtgcgactgcag
tgccagagtggcagtggcttccttgagggcctctttggctgcctgcgccctgtctggacc
atgattggcaaagcctactccactgagcacaagcagcagcaggaagacctttgggaggtc
ccctttgaggaaatcctggacctgcagtgggtgggctcaggggcccagggtgctgtcttc
ctggggcgcttccacggggaggaggtggctgtgaagaaggtgcgagacctcaaagaaacc
gacatcaagcacttgcgaaagctgaagcaccccaacatcatcactttcaagggtgtgtgc
acccaggctccctgctactgcatcctcatggagttctgcgcccagggccagctgtatgag
gtactgcgggctggccgccctgtcaccccctccttactggttgactggtccatgggcatc
gctggtggcatgaactacctgcacctgcacaagattatccacagggatctcaagtcaccc
aacatgctaatcacctacgacgatgtggtgaagatctcagattttggcacttccaaggag
ctgagtgacaagagcaccaagatgtcctttgcagggacagtagcctggatggcccctgag
gtgatccgcaatgaacctgtgtctgagaaggtcgacatctggtcctttggcgtggtgcta
tgggaactgctgactggtgagatcccctacaaagacgtagattcctcagccattatctgg
ggtgtgggaagcaacagtctccatctgcccgtgccctccagttgcccagatggtttcaag
atcctgcttcgccagtgctggaatagcaaaccacgaaatcgcccatcattccgacagatc
ctgctgcatctggacattgcctcagctgatgtactctccacaccccaggagacttacttt
aagtcccaggcagagtggcgggaagaagtaaaactgcactttgaaaagattaagtcagaa
gggacctgtctgcaccgcctagaagaggaactggtgatgaggaggagggaggagctcaga
cacgccctggacatcagggagcactatgaaaggaagctggagagagccaacaacctgtat
atggaacttaatgccctcatgttgcagctggaactcaaggagagggagctgctcaggcga
gagcaagctttagagcggaggtgcccaggcctgctgaagccacacccttcccggggcctc
ctgcatggaaacacaatggagaagcttatcaagaagaggaatgtgccacagaagctgtca
ccccatagcaaaaggccagatatcctcaagacggagtctttgctccctaaactagatgca
gccctgagtggggtggggcttcctgggtgtcctaagggccccccctcaccaggacggagt
cgccgtggcaagacccgtcaccgcaaggccagcgccaaggggagctgtggggacctgcct
gggcttcgtacagctgtgccaccccatgaacctggaggaccaggaagcccagggggccta
ggagggggaccctcagcctgggaggcctgccctcccgccctccgtgggcttcatcatgac
ctcctgctccgcaaaatgtcttcatcgtccccagacctgctgtcagcagcactagggtcc
cggggccggggggccacaggcggagctggggatcctggctcaccacctccggcccggggt
gacaccccaccaagtgagggctcagcccctggctccaccagcccagattcacctggggga
gccaaaggggaaccacctcctccagtagggcctggtgaaggtgtggggcttctgggaact
ggaagggaagggacctcaggccggggaggaagccgggctgggtcccagcacttgacccca
gctgcactgctgtacagggctgccgtcacccgaagtcagaaacgtggcatctcatcggaa
gaggaggaaggagaggtagacagtgaagtagagctgacatcaagccagaggtggcctcag
agcctgaacatgcgccagtcactatctaccttcagctcagagaatccatcagatggggag
gaaggcacagctagtgaaccttcccccagtggcacacctgaagttggcagcaccaacact
gatgagcggccagatgagcggtctgatgacatgtgctcccagggctcagaaatcccactg
gacccacctccttcagaggtcatccctggccctgaacccagctccctgcccattccacac
caggaacttctcagagagcggggccctcccaattctgaggactcagactgtgacagcact
gaattggacaactccaacagcgttgatgccttgcggcccccagcttccctccctccatga |
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