| Entry |
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| Symbol |
MKNK1, MNK1
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| Name |
(RefSeq) MAPK interacting serine/threonine kinase 1
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| KO |
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| Organism |
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| Pathway |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
8569 (MKNK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
8569 (MKNK1)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
8569 (MKNK1)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: CAMK group
MAPKAPK family [OT]
8569 (MKNK1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
1:complement(46557407..46604268)
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| AA seq |
453 aa
MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNG
KEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSI
LAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSS
DPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPE
LTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWD
RGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHP
WVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLC
SMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL |
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| NT seq |
1362 nt +upstreamnt +downstreamnt
atgggcagtagcgaaccccttcccatcgcagatggtgacaggaggaggaagaagaagcgg
aggggccgggccactgactccttgccaggaaagtttgaagatatgtacaagctgacctct
gaattgcttggagagggagcctatgccaaagttcaaggtgccgtgagcctacagaatggc
aaagagtatgccgtcaaaatcatcgagaaacaagcagggcacagtcggagtagggtgttt
cgagaggtggagacgctgtatcagtgtcagggaaacaagaacattttggagctgattgag
ttctttgaagatgacacaaggttttacttggtctttgagaaattgcaaggaggttccatc
ttagcccacatccagaagcaaaagcacttcaatgagcgagaagccagccgagtggtgcgg
gacgttgctgctgcccttgacttcctgcataccaaagacaaagtctctctctgtcaccta
ggctggagtgctatggcgccatcagggctcactgcagccccaacctccctgggctccagt
gatcctcccacctcagcctcccaagtagctgggactacaggcattgctcatcgtgatctg
aaaccagaaaatatattgtgtgaatctccagaaaaggtgtctccagtgaaaatctgtgac
tttgacttgggcagtgggatgaaactgaacaactcctgtacccccataaccacaccagag
ctgaccaccccatgtggctctgcagaatacatggcccctgaggtagtggaggtcttcacg
gaccaggccacattctacgacaagcgctgtgacctgtggagcctgggcgtggtcctctac
atcatgctgagtggctacccacccttcgtgggtcactgcggggccgactgtggctgggac
cggggcgaggtctgcagggtgtgccagaacaagctgtttgaaagcatccaggaaggcaag
tatgagtttcctgacaaggactgggcacacatctccagtgaagccaaagacctcatctcc
aagctcctggtgcgagatgcaaagcagagacttagcgccgcccaagttctgcagcaccca
tgggtgcaggggcaagctccagaaaagggactccccacgccgcaagtcctccagaggaac
agcagcacaatggacctgacgctcttcgcagctgaggccatcgcccttaaccgccagcta
tctcagcacgaagagaacgaactagcagaggagccagaggcactagctgatggcctctgc
tccatgaagctttcccctccctgcaagtcacgcctggcccggagacgggccctggcccag
gcaggccgtggtgaagacaggagcccgcccacagcactctga |
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