| Entry |
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| Symbol |
RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
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| Name |
(RefSeq) receptor interacting serine/threonine kinase 2
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| KO |
| K08846 | receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1] |
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| Organism |
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| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
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| Network |
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| Element |
| N00940 | NOD-NFKB signaling pathway |
| N01112 | Salmonella SopE/E2 to NOD-NFKB signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
8767 (RIPK2)
09160 Human Diseases
09171 Infectious disease: bacterial
05131 Shigellosis
8767 (RIPK2)
05152 Tuberculosis
8767 (RIPK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
8767 (RIPK2)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
8767 (RIPK2)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: TKL group
RIPK family [OT]
8767 (RIPK2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
8:89757816..89791064
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| AA seq |
540 aa
MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSER
KDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPL
RFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRS
SKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMY
SVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEI
TFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPET
SRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIIN
PLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTK
PTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM |
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| NT seq |
1623 nt +upstreamnt +downstreamnt
atgaacggggaggccatctgcagcgccctgcccaccattccctaccacaaactcgccgac
ctgcgctacctgagccgcggcgcctctggcactgtgtcgtccgcccgccacgcagactgg
cgcgtccaggtggccgtgaagcacctgcacatccacactccgctgctcgacagtgaaaga
aaggatgtcttaagagaagctgaaattttacacaaagctagatttagttacattcttcca
attttgggaatttgcaatgagcctgaatttttgggaatagttactgaatacatgccaaat
ggatcattaaatgaactcctacataggaaaactgaatatcctgatgttgcttggccattg
agatttcgcatcctgcatgaaattgcccttggtgtaaattacctgcacaatatgactcct
cctttacttcatcatgacttgaagactcagaatatcttattggacaatgaatttcatgtt
aagattgcagattttggtttatcaaagtggcgcatgatgtccctctcacagtcacgaagt
agcaaatctgcaccagaaggagggacaattatctatatgccacctgaaaactatgaacct
ggacaaaaatcaagggccagtatcaagcacgatatatatagctatgcagttatcacatgg
gaagtgttatccagaaaacagccttttgaagatgtcaccaatcctttgcagataatgtat
agtgtgtcacaaggacatcgacctgttattaatgaagaaagtttgccatatgatatacct
caccgagcacgtatgatctctctaatagaaagtggatgggcacaaaatccagatgaaaga
ccatctttcttaaaatgtttaatagaacttgaaccagttttgagaacatttgaagagata
acttttcttgaagctgttattcagctaaagaaaacaaagttacagagtgtttcaagtgcc
attcacctatgtgacaagaagaaaatggaattatctctgaacatacctgtaaatcatggt
ccacaagaggaatcatgtggatcctctcagctccatgaaaatagtggttctcctgaaact
tcaaggtccctgccagctcctcaagacaatgattttttatctagaaaagctcaagactgt
tattttatgaagctgcatcactgtcctggaaatcacagttgggatagcaccatttctgga
tctcaaagggctgcattctgtgatcacaagaccactccatgctcttcagcaataataaat
ccactctcaactgcaggaaactcagaacgtctgcagcctggtatagcccagcagtggatc
cagagcaaaagggaagacattgtgaaccaaatgacagaagcctgccttaaccagtcgcta
gatgcccttctgtccagggacttgatcatgaaagaggactatgaacttgttagtaccaag
cctacaaggacctcaaaagtcagacaattactagacactactgacatccaaggagaagaa
tttgccaaagttatagtacaaaaattgaaagataacaaacaaatgggtcttcagccttac
ccggaaatacttgtggtttctagatcaccatctttaaatttacttcaaaataaaagcatg
taa |
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