| Entry |
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| Symbol |
KALRN, ARHGEF24, CHD5, CHDS5, DUET, DUO, HAPIP, KALNC2, TRAD
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| Name |
(RefSeq) kalirin RhoGEF kinase
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| KO |
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| Organism |
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| Disease |
| H01742 | Coronary artery disease |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
8997 (KALRN)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
8997 (KALRN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
8997 (KALRN)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
8997 (KALRN)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: CAMK group
Trio family [OT]
8997 (KALRN)
Membrane trafficking [BR:hsa04131]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
8997 (KALRN)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
8997 (KALRN)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
3:124033369..124726325
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| AA seq |
2986 aa
MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
GSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPS
ERPGWCLVRTTERSPPLEGLVPSSALCISHSRSSVEMDCFFPLVKDAYSHSSSENGGKSE
SVANLQAQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVRDGRKSF
DLGSPKPGDETTPQGDSADEKSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQDEMSSSLL
AARQASTEVPTAADLVNAIEKLVKNKLSLEGSSYRGSLKDPAGCLNEGMAPPTPPKNPEE
EQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIH
QIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEYDAYFE
EVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKR
CNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELL
RKGSLTPGYMFKRSIKMNYLVLEENVDNDPCKFALMNRETSERVVLQAANADIQQAWVQD
INQVLETQRDFLNALQSPIEYQRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGS
SYNPPLPPLKISTSNGSPGFEYHQPGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEI
CVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSDGSIKKS
CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI
LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT
YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER
SCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQF
RVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKK
CIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTSYILILELM
DDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRV
KLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPF
LDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQP
HNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT |
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| NT seq |
8961 nt +upstreamnt +downstreamnt
atgacggaccgcttctgggaccagtggtatctctggtatctccgcttgctccggctgctg
gatcgagggtcttttcggaatgatggtttgaaagcttctgatgtccttcctatcctaaag
gaaaaggtggccttcgtgtctgggggtcgtgataagcgaggcggacccatcctgaccttc
cctgctcgcagcaatcatgacagaataagacaggaagacctgcggaaactcgtgacgtat
ttggccagcgtgccaagtgaggacgtgtgcaaacgtggcttcactgtcatcatcgacatg
cggggctccaagtgggacctcatcaagcccctcctcaaaacgctgcaggaagcctttcca
gctgagatccatgtggccctcatcattaaacccgacaacttctggcagaaacagaagacc
aactttggcagctccaaattcatctttgagacgagcatggtatctgtggagggcctcaca
aagctggtggacccctcccagctgacggaggagtttgatggctccctggactacaaccat
gaggagtggatcgaactgcggctctccctggaggagttcttcaacagcgccgtgcacctg
ctctcgcgcctcgaggacctccaggagatgctagcccggaaggagtttcctgtggatgtg
gagggctctcggcggctcattgacgaacacacacagctcaagaaaaaggtgctgaaggcc
cctgtggaggagctggaccgggaggggcagcggctgctgcagtgcatccgctgcagcgac
ggcttctcaggacgcaactgcatcccgggcagtgctgacttccagagcctggtgcccaag
atcaccagtctcctggacaagctgcactccacccggcagcacctgcaccagatgtggcat
gtgcgcaagctcaagctggaccagtgctttcagctgcggctcttcgagcaggatgctgag
aagatgtttgactggataagccacaacaaggagttattcctccagagccacacggagatc
ggagtcagctaccagtacgcccttgacctccagacgcagcacaatcactttgccatgaac
tccatgaatgcctatgtcaacatcaaccgcatcatgtccgtggcttcccgcctctctgag
gccggtcattatgcctcacaacaaatcaagcagatctccacccagctggaccaggagtgg
aagagcttcgctgctgccctggatgaacgcagcaccatcctcgccatgtctgctgtgttc
caccagaaggctgagcagttcctgtcgggagtggatgcctggtgcaagatgtgcagtgaa
ggtggtctgccatccgagatgcaagacctagagctggcaatccaccaccaccagaccttg
tatgagcaggtgacccaagcctacacagaggtcagccaggatggcaaagcactacttgat
gtgctgcagcggcccctgagccctgggaactccgaatccctcacggccacagccaactac
tccaaggcagtgcaccaggtgctggacgtggtgcatgaggtgttacatcaccagcgacgg
ctggagagcatctggcagcaccgcaaggtgcggctccaccagcggctgcagctctgcgtc
ttccagcaggatgtacagcaggtgttggactggattgaaaaccatggtgaggcctttctc
agcaaacacactggagttgggaagtccctacatcgagcccgggccctgcagaagaggcat
gatgactttgaagaggtggctcagaatacgtacaccaatgcggacaagctcctagaagca
gcagagcagttggctcagacgggggaatgtgaccccgaggagatctacaaggcagctcga
cacctggaggtgcgcatccaagacttcgtgcgcagggtggagcagcggaagcttctcctg
gacatgtctgtttccttccacacacacaccaaagagttgtggacatggatggaagacctt
cagaaggagatgttggaggatgtctgtgcagattctgtggatgcagtccaggaactgatc
aagcagttccagcagcagcagaccgccactctagatgccacactcaatgtcatcaaggaa
ggcgaagaccttatccagcagctcaggtcagcgcctccctccctcggggagcccagcgag
gccagggactcggctgtgtccaacaacaaaacaccccacagcagctccatcagccacatc
gagtcggtcctgcagcagcttgatgatgcccaggtgcagatggaggagctgttccacgag
cggaagatcaagctggacatcttcctgcaactgcgcatctttgagcagtacaccatcgag
gtgacagcagagctagacgcctggaatgaagacttgcttcggcagatgaatgacttcaac
acagaggacctaaccctggcagaacagcggctgcagcgccacacagaacggaagctagcc
atgaacaacatgacctttgaggttatccagcagggacaggatctgcaccagtacatcacg
gaggtccaggcatcaggaattgagttgatctgtgaaaaagacattgatctggcagcccag
gtgcaagagttattggaatttctccatgagaagcagcatgaattggagctcaatgcagag
cagactcataagcggctagagcagtgcctccaattacgtcacctccaggctgaagtcaaa
caggttctgggatggatccgcaatggagagtcaatgctcaacgccagcctggtcaatgcc
agctctttgtcggaagcagagcagctgcagcgggagcacgagcagttccaactggccatc
gagtccctctttcatgccacttccttgcagaagacgcaccagagtgccctgcaggtacag
cagaaagccgaggtgctgctccaggccggccactacgatgccgatgccatccgggaatgt
gctgagaaggtggccctccactggcagcagctcatgctgaagatggaagaccggctaaaa
ttggtcaatgcctctgtggccttttacaaaacttctgaacaggtgtgtagtgtcctggag
agcttagagcaagaataccggagagatgaggactggtgtggtggacgagataagctgggg
ccagcagcagagatcgaccatgtcattcccctcatcagcaaacatttggaacaaaaggag
gcctttcttaaggcctgcaccctggctcggcggaatgctgaggtgtttctcaagtacatc
cacaggaacaacgtcagcatgcccagtgtcgccagccacactcggggacccgagcaacaa
gtgaaagccatcctgagtgagctcctgcagagggagaatcgcgtgctgcatttctggacc
ttgaagaagcggcggttagaccaatgccagcaatatgtggtgttcgagcgcagcgctaag
caggcgcttgactggatccaagaaacaggtgaattttacctctcaacacatacctccact
ggagagaccacagaggagactcaggaactgctgaaagaatatggggaattcagggtgcct
gccaagcaaacaaaggagaaggtgaagcttctgattcagctggccgatagctttgtggaa
aaaggccacattcatgccacggagataaggaaatgggtgaccacggtggacaagcactac
agagatttctccctgaggatgggaaagtaccgatactcactggagaaagccctaggagtc
aacacagaggataataaggacctggagctggatattatcccagcaagcctttcggatcgg
gaggtcaagctgcgggacgccaaccacgaagtcaatgaagagaagcggaagtcagcccgg
aagaaagaatttattatggctgaactactccagacagagaaggcttatgtaagggatttg
catgagtgcttagagacctacctgtgggaaatgaccagtggtgtggaggagatcccccct
gggatcctcaataaagagcatatcatctttggcaacatccaagagatctacgatttccat
aacaacatcttcctcaaagagctggagaagtacgagcaactgcctgaggatgtgggacac
tgctttgttacctgggcagacaaatttcagatgtatgtcacctactgtaaaaacaagcct
gattccaaccagcttatcctggagcatgcgggcaccttctttgatgagatacaacagcgg
catggtctggccaactccatctcttcctacctaattaagcctgtccaaaggatcaccaaa
tatcaactgctcctgaaggaacttttaacttgctgtgaagaagggaaaggggagctcaag
gatggcctggaggtgatgctcagtgtcccaaagaaagccaatgatgccatgcatgtcagc
atgctggaagggttcgacgagaacctggatgtgcagggggagttgattctccaggatgcc
tttcaagtgtgggacccgaagtcgctgatccggaaggggcgggagcggcacttgttcctc
tttgagatctccttggtttttagcaaggagatcaaagattcttcaggacacacgaaatat
gtttacaagaacaagctactgacctcagagctgggtgtgaccgagcacgtggagggcgat
ccctgcaaattcgccttgtggtctgggcgcaccccatcctcagacaataaaacagtgctg
aaagcctccaacattgaaaccaagcaggagtggatcaagaacattcgagaagtgattcaa
gaaaggatcattcacctgaaaggagctttaaaggagccacttcagctccccaaaacacca
gccaaacagaggaacaatagtaagagggatggagtggaggatattgacagccagggggat
gggagcagccaaccagacaccatctccattgcttctaggacctctcagaacacagtggac
agtgacaagctctctggtggatgtgagctgacagtggtcctccaggacttcagtgcgggc
cacagcagtgagctgaccatccaggtggggcagacggtagagctgctggagcggcccagc
gagcggcctggttggtgtctggtccgtaccaccgaacggagcccgcccttggagggtctg
gtccccagcagcgccctgtgcatctcacactcccgaagcagcgtggagatggactgcttc
ttccccttggtgaaagatgcatactctcattcctcaagcgagaatggaggcaagtccgag
tccgtggccaacctgcaggcccagccctccctgaactccatccacagttccccgggtccc
aagcgctccaccaacactcttaagaagtggctgacgagtcctgtgcgtcggcttaacagc
gggaaggcagatggaaacatcaaaaagcagaagaaagttcgcgatggtcggaagagcttt
gacctgggatctcccaagcctggggatgaaacaacccctcagggagacagcgctgatgag
aagagcaagaaaggttggggtgaagatgagccggatgaagagtcacacacacccctccca
ccacctatgaagatttttgacaacgaccctacacaggatgaaatgtcctcctctttgcta
gcagcccggcaggcttccactgaagtacctactgctgcagaccttgtcaatgcaatagaa
aagttggtcaaaaacaagctgagtctagaaggaagctcataccgggggagcttgaaagac
cctgcaggctgcctgaatgaggggatggccccacccacacctcctaaaaacccagaagaa
gaacagaaagccaaggccctgagaggcaggatgtttgtcctgaatgagctggtacagaca
gagaaagactatgtcaaggatctgggcattgtggtggagggcttcatgaagagaatagaa
gaaaagggtgtccctgaggatatgcgaggaaaggacaaaatcgtgtttggaaatattcat
cagatttatgactggcataaggattttttcctggcggaactggaaaagtgtatccaggag
caagacagattggcacagctctttattaagcacgagcggaagctgcacatctacgtgtgg
tattgtcagaataagccgcgctcagagtacatcgttgctgagtatgacgcctactttgag
gaggtaaaacaggagataaatcagaggctgacactgagtgacttcctcatcaagcccatt
cagagaataacaaaataccagttgctcctcaaggacttcctgagatacagtgagaaggct
ggtttggagtgttcagatattgagaaagcagtggagttaatgtgccttgttcccaaacgc
tgcaatgacatgatgaatctaggacgtctgcagggctttgagggcactctgactgctcag
gggaagctgctgcagcaggacacattctatgtgatcgagctggatgcaggcatgcagtcc
cggaccaaagagaggcgcgtgttcctcttcgagcagattgtcatcttcagtgaactgctc
aggaagggatccctcacccctggctacatgttcaaaaggagcatcaagatgaattacttg
gtcctggaggagaatgtggacaatgatccctgcaagtttgcactcatgaacagagagact
tctgagagggttgttctgcaagccgccaacgctgacatccagcaggcctgggtgcaggac
atcaatcaagtcttagaaacacagcgagactttttgaatgcactgcaatcgcccattgag
tatcaacggaaagaaaggagcacagctgtgatgaggtctcaacctgccaggcttccccaa
gccagccccaggccctactcctctgttcctgcgggctcagagaagcccccaaagggctcc
agctataacccacctctgcctcccctgaagatatctacctccaatggcagtccagggttt
gaataccaccagcctggggacaagttcgaagccagcaagcagaacgacctgggaggctgc
aatgggacctcgtccatggccgtgatcaaagattactatgcactgaaggagaatgaaatc
tgtgtgagccaaggtgaggtggtccaggtcctcgccgtcaaccagcagaacatgtgtctg
gtgtaccagcctgccagcgaccattcccccgccgccgagggctgggtcccaggcagcatc
ctggcgcccctcaccaaagccacagcagcagaaagtagtgacgggagcatcaagaagtca
tgttcatggcatactctacgcatgagaaagcgggcggaagtggagaacacgggtaaaaat
gaagccacagggcctcgtaaacccaaggatattctgggcaacaaagtctctgttaaagag
acgaacagttccgaggaatcagagtgtgatgatcttgaccctaatactagcatggagatc
ttaaatccaaatttcatccaagaagtggccccagaattccttgtgcccttggtggatgtg
acctgcttgcttggggacacagtgatactgcagtgcaaagtctgtgggcggccaaagccc
accatcacttggaagggtccagaccagaacatccttgacactgataacagctcagccaca
tacacggtctcctcttgtgattctggagaaatcaccctgaagatctgtaatctgatgccc
caagacagtgggatttatacctgcatagcaacaaatgaccacgggaccacatcaacgtct
gcaacagtcaaagtgcaaggtgttccagcagcccctaaccgccccattgcccaggagaga
agctgcacctccgtgattctccgctggctgcccccctccagcacaggaaactgcactatt
tctggttacactgtggagtacagagaggaaggttctcagatctggcagcagtcagtggct
tcgaccttggacacttacctcgtcatcgaagaccttagtcccgggtgtccttatcagttc
agagtcagtgccagtaacccctggggaatcagccttcccagcgagccctcggagtttgtg
cgacttccagaatatgatgctgctgctgatggtgccaccatttcttggaaggaaaatttt
gactcagcttacactgagctgaatgaaattggaagaggccgtttctctatagtaaagaaa
tgcattcacaaagctacccgcaaagatgtggctgtgaaatttgttagcaaaaaaatgaag
aagaaagaacaggctgcccacgaggctgccctgcttcagcacctacagcacccccagtac
atcactctccatgacacctatgagtcccccacatcctacatcctgatcttggaactgatg
gatgatggccggctcttagactaccttatgaatcatgatgaactgatggaggaaaaagta
gctttctatatccgagacatcatggaggctctgcagtaccttcacaactgcagggttgca
catttggacataaagcctgaaaacctgctcattgacctacggattccagtgcctcgagtg
aagctcattgacttggaggatgctgtccagatctcgggtcacttccacattcaccacctg
ctggggaaccctgagtttgctgccccagaagtcattcaaggcatccccgtctccctgggg
acagacatctggagcatcggggttctgacatatgtcatgctgagtggggtctcccccttc
ttggatgagagcaaagaggagacatgtatcaacgtatgcagggtggatttcagcttcccc
catgaatacttctgtggtgtgagcaatgctgccagagatttcatcaatgtgatcttacag
gaagattttcggaggcggcccacagcagccacatgcttgcagcatccatggctgcagccc
cataatggcagctactctaagatccccctggacacctcccgcctagcatgcttcatagaa
cgtcgcaagcaccagaatgatgtgcggcctattcccaatgtcaagagctacattgtcaac
cgggtgaaccaagggacgtag |
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