| Entry |
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| Symbol |
CDK1, CDC2, CDC28A, P34CDC2
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| Name |
(RefSeq) cyclin dependent kinase 1
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| KO |
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| Organism |
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| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
| hsa05170 | Human immunodeficiency virus 1 infection |
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| Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06161 Human immunodeficiency virus 1 (HIV-1) nt06230 Cell cycle (cancer) nt06512 Chromosome cohesion and segregation |
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| Element |
| N00456 | HIV Vpr to CDC25-cell cycle G2M |
| N00457 | HIV Vpr to cell cycle G2M |
| N00460 | HIV Vpr to WEE1-cell cycle G2M |
| N00499 | ATR-p21-Cell cycle G2/M |
| N01485 | Cohesin dissociation in prophase |
| N01499 | Modifying of condensin II subunits |
| N01500 | Modifying of condensin I subunits |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
983 (CDK1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
983 (CDK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
983 (CDK1)
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:hsa03032]
983 (CDK1)
03036 Chromosome and associated proteins [BR:hsa03036]
983 (CDK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
983 (CDK1)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.22 cyclin-dependent kinase
983 (CDK1)
2.7.11.23 [RNA-polymerase]-subunit kinase
983 (CDK1)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: CMGC group
CDK family
983 (CDK1)
DNA replication proteins [BR:hsa03032]
Eukaryotic type
DNA Replication Termination Factors
Prevention of re-replication factors
983 (CDK1)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
983 (CDK1)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
983 (CDK1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
10:60778331..60794852
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| AA seq |
297 aa
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM |
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| NT seq |
894 nt +upstreamnt +downstreamnt
atggaagattataccaaaatagagaaaattggagaaggtacctatggagttgtgtataag
ggtagacacaaaactacaggtcaagtggtagccatgaaaaaaatcagactagaaagtgaa
gaggaaggggttcctagtactgcaattcgggaaatttctctattaaaggaacttcgtcat
ccaaatatagtcagtcttcaggatgtgcttatgcaggattccaggttatatctcatcttt
gagtttctttccatggatctgaagaaatacttggattctatccctcctggtcagtacatg
gattcttcacttgttaagagttatttataccaaatcctacaggggattgtgttttgtcac
tctagaagagttcttcacagagacttaaaacctcaaaatctcttgattgatgacaaagga
acaattaaactggctgattttggccttgccagagcttttggaatacctatcagagtatat
acacatgaggtagtaacactctggtacagatctccagaagtattgctggggtcagctcgt
tactcaactccagttgacatttggagtataggcaccatatttgctgaactagcaactaag
aaaccacttttccatggggattcagaaattgatcaactcttcaggattttcagagctttg
ggcactcccaataatgaagtgtggccagaagtggaatctttacaggactataagaataca
tttcccaaatggaaaccaggaagcctagcatcccatgtcaaaaacttggatgaaaatggc
ttggatttgctctcgaaaatgttaatctatgatccagccaaacgaatttctggcaaaatg
gcactgaatcatccatattttaatgatttggacaatcagattaagaagatgtag |
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