| Entry |
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| Symbol |
Fgfr1, Eask, FGFR-I, FLG, Fgfr-1, Flt-2, Fr1, Hspy, MFR, bFGF-R-1, c-fgr
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| Name |
(RefSeq) fibroblast growth factor receptor 1
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu04550 | Signaling pathways regulating pluripotency of stem cells |
| mmu04810 | Regulation of actin cytoskeleton |
| mmu04928 | Parathyroid hormone synthesis, secretion and action |
| mmu05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
14182 (Fgfr1)
04015 Rap1 signaling pathway
14182 (Fgfr1)
04151 PI3K-Akt signaling pathway
14182 (Fgfr1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
14182 (Fgfr1)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
14182 (Fgfr1)
09159 Environmental adaptation
04714 Thermogenesis
14182 (Fgfr1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
14182 (Fgfr1)
05205 Proteoglycans in cancer
14182 (Fgfr1)
05230 Central carbon metabolism in cancer
14182 (Fgfr1)
09162 Cancer: specific types
05218 Melanoma
14182 (Fgfr1)
05215 Prostate cancer
14182 (Fgfr1)
05224 Breast cancer
14182 (Fgfr1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
14182 (Fgfr1)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:mmu04090]
14182 (Fgfr1)
00536 Glycosaminoglycan binding proteins [BR:mmu00536]
14182 (Fgfr1)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
14182 (Fgfr1)
Protein kinases [BR:mmu01001]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
14182 (Fgfr1)
CD molecules [BR:mmu04090]
Proteins
14182 (Fgfr1)
Glycosaminoglycan binding proteins [BR:mmu00536]
Heparan sulfate / Heparin
Growth factors/receptors
14182 (Fgfr1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
8:26008808..26067819
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| AA seq |
822 aa
MWGWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDD
VQSINWLRDGVQLVESNRTRITGEEVEVRDSIPADSGLYACVTSSPSGSDTTYFSVNVSD
ALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVL
GKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDL
VSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNG
RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD
KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPLDQYSPSF
PDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTQLANSGLKRR |
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| NT seq |
2469 nt +upstreamnt +downstreamnt
atgtggggctggaagtgcctcctcttctgggctgtgctggtcacagccactctctgcact
gccaggccagccccaaccttgcctgaacaagctcagccctggggagtccctgtggaagtg
gagtctctcctggtccaccctggcgacctgctacagcttcgctgtcggcttcgcgatgat
gtgcagagcatcaactggctgcgggatggggtgcagctggtggagagcaaccgtacccgc
atcacaggggaggaggtggaggtgcgggactccatccccgctgactctggcctctacgct
tgcgtgaccagcagcccctctggcagcgataccacctacttctccgtcaatgtctcagat
gcactcccatcctcggaagatgatgacgacgacgatgactcctcctcggaggagaaagag
acggacaacaccaaaccaaaccgtaggcctgtagctccctactggacatccccagagaaa
atggagaagaaactgcatgcggtgcccgctgccaagacggtgaagttcaagtgcccgtcg
agtgggacacccaaccccactctgcgctggttgaaaaatggcaaagagtttaagcctgac
caccgaattggaggctacaaggttcgctatgccacctggagcatcataatggattctgtg
gtgccttctgacaagggcaactacacctgcatcgtggagaatgagtatgggagcatcaac
cacacctaccagcttgacgtcgtggaacgatctccgcaccgacccatccttcaggcaggg
ctgcctgccaacaagacagtggccctgggcagcaatgtggagttcatgtgtaaggtgtac
agcgatccgcagcctcacattcagtggctgaagcacatcgaggtgaacgggagtaagatc
gggccagacaacttgccgtatgtccagatcctgaagactgctggagttaataccaccgac
aaggaaatggaggtgcttcatctacggaatgtctcctttgaggatgcgggggagtatacg
tgcttggcgggtaactctatcggactctcccatcactctgcatggttgaccgttctggaa
gccctggaagagagaccagctgtgatgacctcaccgctctacctggagatcattatctac
tgcaccggggccttcctgatctcctgcatgttgggctctgtcatcatctataagatgaag
agcggcaccaagaagagcgacttccatagccagatggctgtgcacaagctggccaagagc
atccctctgcgcagacaggtaacagtgtcagctgactccagtgcatccatgaactctggg
gttctcctggttcggccctcacggctctcctccagcgggacccccatgctggctggagtc
tccgaatatgagctccctgaggatccccgctgggagctgccacgagacagactggtctta
ggcaaaccacttggcgagggctgcttcgggcaggtggtgttggctgaggccatcgggctg
gataaggacaaacccaaccgtgtgaccaaagtggccgtgaagatgttgaagtccgacgca
acggagaaggacctgtcggatctgatctcggagatggagatgatgaaaatgattgggaag
cacaagaatatcatcaaccttctgggagcgtgcacacaggatggtcctctttatgtcatt
gtggagtacgcctccaaaggcaatctccgggagtatctacaggcccggaggcctcctggg
ctggagtactgctataaccccagccacaaccccgaggaacagctgtcttccaaagatctg
gtatcctgtgcctatcaggtggctcggggcatggagtatcttgcctctaagaagtgtata
caccgagacctggctgctaggaacgtcctggtgaccgaggataacgtaatgaagatcgca
gactttggcttagctcgagacattcatcatatcgactactacaagaaaaccaccaacggc
cggctgcctgtgaagtggatggcccctgaggcgttgtttgaccggatctacacacaccag
agcgatgtgtggtcttttggagtgctcttgtgggagatcttcactctgggtggctcccca
taccccggtgtgcctgtggaggaacttttcaagctgctgaaggagggtcatcgaatggac
aagcccagtaactgtaccaatgagctgtacatgatgatgcgggactgctggcatgcagtg
ccctctcagagacctacgttcaagcagttggtggaagacctggaccgcattgtggccttg
acctccaaccaggagtatctggacctgtccataccgctggaccagtactcacccagcttt
cccgacacacggagctccacctgctcctcaggggaggactctgtcttctctcatgagccg
ttacctgaggagccctgtctgcctcgacaccccacccagcttgccaacagtggactcaaa
cggcgctga |
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