KEGG T01002: 18761

Mus musculus (house mouse): 18761

Entry

18761             CDS       T01002

Symbol

Prkcq, A130035A12Rik, PKC-0, PKC-theta, PKCtheta, Pkcq

Name

(RefSeq) protein kinase C, theta

K18052

novel protein kinase C theta type [EC:2.7.11.13]

Organism

mmu Mus musculus (house mouse)

Pathway

mmu04064

NF-kappa B signaling pathway

mmu04140

Autophagy - animal

mmu04270

Vascular smooth muscle contraction

mmu04658

Th1 and Th2 cell differentiation

mmu04659

Th17 cell differentiation

mmu04660

T cell receptor signaling pathway

mmu04750

Inflammatory mediator regulation of TRP channels

mmu04920

Adipocytokine signaling pathway

mmu04931

Insulin resistance

mmu05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    18761 (Prkcq)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    18761 (Prkcq)
09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    18761 (Prkcq)
   04658 Th1 and Th2 cell differentiation
    18761 (Prkcq)
   04659 Th17 cell differentiation
    18761 (Prkcq)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    18761 (Prkcq)
09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    18761 (Prkcq)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    18761 (Prkcq)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    18761 (Prkcq)
Enzymes [BR:mmu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     18761 (Prkcq)
Protein kinases [BR:mmu01001]
Serine/threonine kinases: AGC group
  PKC family [OT]
   18761 (Prkcq)

SSDB

Motif

Pfam:

Pkinase PKC_C2 PK_Tyr_Ser-Thr C1_1 Pkinase_C ABC1 Kinase-like C1_2 zf-RING-like Haspin_kinase PHDvar_NSD

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

MGI:

Ensembl:

UniProt:

Structure

LinkDB

Position

2:11176922..11306033

AA seq 707 aa
MSPFLRIGLSNFDCGTCQACQGEAVNPYCAVLVKEYVESENGQMYIQKKPTMYPPWDSTF
DAHINKGRVMQIIVKGKNVDLISETTVELYSLAERCRKNNGRTEIWLELKPQGRMLMNAR
YFLEMSDTKDMSEFENEGFFALHQRRGAIKQAKVHHVKCHEFTATFFPQPTFCSVCHEFV
WGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYK
SPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLMAEALAMIESTQQ
ARSLRDSEHIFREGPVEIGLPCSTKNETRPPCVPTPGKREPQGISWDSPLDGSNKSAGPP
EPEVSMRRTSLQLKLKIDDFILHKMLGKGSFGKVFLAEFKRTNQFFAIKALKKDVVLMDD
DVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSR
ATFYAAEVILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADFGMCKENMLGDAKTNTFC
GTPDYIAPEILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR
WLEREAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPYD
CSNFDKEFLSEKPRLSFADRALINSMDQNMFSNFSFINPGMETLICS

NT seq 2124 nt +upstreamnt +downstreamnt
atgtcaccgtttcttcgaatcggtttatccaactttgactgtgggacctgccaagcttgt
cagggagaggcagtgaacccctactgcgctgtgcttgtcaaagagtatgtggaatcagaa
aatgggcagatgtacatccagaaaaagccaaccatgtacccaccttgggacagcaccttt
gacgcccacattaacaagggaagggtgatgcagatcatcgtgaagggcaagaatgtagac
ctcatctcagaaacaaccgtggaactctactccctggcggagagatgccgcaagaacaat
gggcggacagaaatatggttagagctgaaacctcaaggccgaatgctaatgaatgcaaga
tactttctggaaatgagtgacacaaaggacatgagtgagtttgagaatgaaggattcttt
gcactgcatcagcgccgaggagccatcaaacaggccaaagtccaccatgtcaagtgtcac
gagttcacggccacctttttccctcaacccacattttgctctgtctgccatgaatttgtc
tggggcctgaacaagcagggttaccagtgccgacagtgtaatgcagcgattcacaagaag
tgcattgataaagtgatagccaagtgcacaggatccgcaatcaatagccgagaaaccatg
ttccataaggagagattcaagatcgacatgccacacagattcaaagtctacaactacaag
agtccaaccttctgtgagcactgtggtaccctgctctgggggctggcgaggcaaggactc
aaatgtgatgcatgtggcatgaacgtccaccaccgatgccagacaaaggttgccaatctt
tgtggtataaaccagaagctaatggctgaagcactagcgatgattgaaagcacccaacag
gctcgctccttacgagattcagaacacatcttccgagaaggcccagttgaaattggtctc
ccatgctccaccaaaaacgaaaccaggccaccatgcgtaccaacacctgggaaaagagaa
ccccagggcatttcctgggattcccctttggatgggtcaaataaatcggccggtcctcct
gaacccgaagtgagcatgcgcaggacttcactgcagctgaaactgaagatcgatgacttc
atcctgcacaagatgttgggaaaaggaagttttggcaaggtcttcctggcagagttcaag
agaaccaatcagtttttcgcaataaaagccttaaagaaagatgtggtgttgatggatgat
gacgtcgagtgtacaatggtggaaaagagggttctgtccttggcatgggagcatccattt
ctaacacacatgttctgcacattccagaccaaggaaaatctctttttcgtgatggagtat
ctcaatggaggcgacttaatgtaccacatccaaagttgccacaaatttgatctttccaga
gccacgttttatgctgctgaggtcatccttggtctgcagttccttcattccaaaggaatt
gtctacagggacctgaagcttgataatatcctgttagacagagatggacatatcaaaata
gcagactttgggatgtgcaaagagaacatgctaggagatgcgaagacaaatactttctgt
ggaactcctgactacattgctccggagatcttgctgggtcagaagtacaaccattccgtc
gactggtggtccttcggggtgctcgtttatgagatgctgattggccagtcccccttccac
gggcaggacgaggaggagctgttccactccatccgcatggacaaccccttctacccgagg
tggctcgaaagggaggccaaggaccttctagtgaagctttttgtgagagaacctgagaag
aggctgggagtgagaggagacatccgccagcatcctttgtttcgagagatcaactgggaa
gagcttgaaaggaaagagattgacccacccttcagaccaaaagtgaaatcaccatatgac
tgtagcaatttcgacaaggaattcctaagtgagaaaccccggctatcattcgccgacaga
gcactcatcaacagcatggaccagaacatgttcagcaacttttccttcattaacccaggg
atggagactctcatttgctcctga

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