| Entry |
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| Symbol |
Ret, PTC, RET51, RET9, c-Ret
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| Name |
(RefSeq) ret proto-oncogene
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
19713 (Ret)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
19713 (Ret)
05230 Central carbon metabolism in cancer
19713 (Ret)
09162 Cancer: specific types
05216 Thyroid cancer
19713 (Ret)
05223 Non-small cell lung cancer
19713 (Ret)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
19713 (Ret)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
19713 (Ret)
Protein kinases [BR:mmu01001]
Receptor tyrosine kinases (RTK)
RET family
19713 (Ret)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
6:complement(118128709..118174705)
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| AA seq |
1115 aa
MAKATSGAAGLGLKLILLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAP
GEVPSFRLGQHLYGVYRTRLHENDWIRINETTGLLYLNQSLDHSSWEQLSIRNGGFPLLT
IFLQVFLGSTAQREGECHWPGCTRVYFSFINDTFPNCSSFKAQDLCIPETAVSFRVRENR
PPGTFYHFHMLPVQFLCPNISVKYSLLGGDSLPFRCDPDCLEVSTRWALDRELREKYVLE
ALCIVAGPGANKETVTLSFPVTVYDEDDSAPTFSGGVGTASAVVEFKRKEGTVVATLQVF
DADVVPASGELVRRYTNTLLSGDSWAQQTFRVEHSPIETLVQVNNNSVRATMHNYKLILN
RSLSISESRVLQLAVLVNDSDFQGPGAGGILVLHFNVSVLPVTLNLPRAYSFPVNKRARR
YAQIGKVCVENCQEFSGVSIQYKLQPSSINCTALGVVTSPEDTSGTLFVNDTEALRRPEC
TKLQYTVVATDRQTRRQTQASLVVTVEGTSITEEVGCPKSCAVNKRRPECEECGGLGSPT
GRCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDAVESRDANICPQDCLRADIVGGHERGE
RQGIKAGYGICNCFPDEKKCFCEPEDSQGPLCDALCRTIITAALFSLIISILLSIFCVCH
HHKHGHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSTENQVPVDSFKIPEDPKWEF
PRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLL
KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSSSLD
HPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDV
YEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPER
LFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLA
ASTPSDSLLYDDGLSEEETPLVDCNNAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTR
ADGTSTGFPRYANDSVYANWMVSPSAAKLMDTFDS |
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| NT seq |
3348 nt +upstreamnt +downstreamnt
atggcgaaagcgacgtccggcgccgcagggctggggctgaagctgattttgctcctgccg
ctgctaggagaagccccactgggcctctatttctcaagggatgcttactgggagaggctg
tatgtagaccagccagctggcacacctctgctctatgtccatgccctacgggatgcccct
ggagaagtgccgagcttccgcctgggccagcatctctatggcgtctaccgtacacggctg
catgagaatgactggatccgcatcaatgagactactggccttctctacctcaatcagagc
ctggaccacagttcctgggaacagctcagcatccgcaatggtggtttccccctgctcacc
atcttcctccaggtctttctggggtccacagcccagagagagggagaatgccattggcca
ggctgtacccgtgtgtacttctccttcatcaacgacaccttcccaaattgtagctccttc
aaagcccaggatctctgcatcccagagacagccgtgtccttccgagtcagggagaacagg
cctcctggcaccttctaccacttccacatgttacccgtgcagttcctttgtcccaacatc
agtgtgaagtacagtctcttaggaggggatagtctgcccttccgttgtgacccagactgc
ctggaggtgagcactcgctgggccctggatcgagagctccgggagaagtatgtgctggag
gctttgtgcatagtggcaggccctggtgccaacaaagagacggtgactctgtccttccca
gtgacagtgtatgatgaggacgactcggcgcccaccttctctggaggtgtgggcactgcc
agcgcggtggtggagtttaagcggaaggagggcactgtggtggccaccctgcaggtgttc
gatgcagatgtggtgccagcgtctggggagctggtgagacggtacacaaacacactcctc
tcaggggactcctgggcccagcagaccttccgggtggagcattcgcccatcgagaccttg
gtccaggtcaacaacaactccgttcgggcaaccatgcacaattacaagctgattctcaac
aggagcctgtctatctcagagagccgagtcctgcagctcgcggtcctggtcaacgactca
gacttccaggggcctggggcaggtggtatcctcgtcctccatttcaacgtgtctgtactg
cccgtcaccctgaacctacccagggcctactccttcccagtgaataagagggcccgccgc
tatgcccagatcgggaaagtctgtgtggaaaactgccaggagttcagcggtgtctccatc
cagtacaagctgcagccttccagcatcaactgcactgccctaggtgtggtcacctcaccc
gaggacacctcggggaccctatttgtaaatgacacagaggccctgcggcgacctgagtgc
accaagcttcagtacacggtggtagccactgaccggcagacccgcagacagacccaggct
tcgctagtggtcactgtggaggggacatccattactgaagaagtaggctgccccaagtcc
tgtgcagtaaacaagaggcgccccgagtgtgaggaatgtggtggcctgggttctccaact
ggcaggtgcgagtggcgccagggagatggtaaagggatcaccaggaacttctccacctgc
tcccccagtaccaggacctgccccgacggccactgtgatgctgtggagagccgggatgcc
aacatttgcccccaggactgtctccgtgccgacattgttggaggacacgagcgaggggag
cgccagggcattaaagcaggctacggcatctgcaactgtttccctgatgagaagaaatgc
ttctgcgagccagaggacagccagggcccactgtgtgatgcgctgtgccgcacgatcatc
acagctgccctcttctcccttatcatctccatcctgctgtccatcttctgtgtctgccac
caccacaagcatgggcacaagccgcccattgcatcagcggaaatgaccttctgccggccg
gcccagggcttcccaatcagttattcctcctcaggcacccgccggccctcactggattcc
acggagaaccaggttcctgtggactctttcaagatcccggaggatccaaagtgggaattt
cctcggaagaacttagttcttgggaaaactctgggagaaggcgagtttggaaaagttgtc
aaggccacagccttccgtctgaaaggccgggcaggatacaccacagtggctgtgaaaatg
ctgaaagaaaacgcctcccagagtgagttacgagacctgctgtctgagttcaaccttctg
aaacaagtcaaccatccacatgtcatcaagttgtatggggcctgcagccaggatgggcca
cttcttctcattgtggagtatgccaagtatggctccctgcggggattcctccgtgacagc
cgcaagattgggcctgcctatgtgagcggtggaggcagccgcaactccagctcgctggac
cacccagatgaaagggtactgaccatgggtgacctcatctccttcgcctggcagatctcg
aggggtatgcagtacttggcagaaatgaagcttgtacatcgggacttagctgccaggaac
atcttggtggctgagggacggaagatgaagatttccgactttgggctgtcccgagatgtt
tatgaggaagattcctatgtgaagaaaagcaagggccggattcccgtcaagtggatggca
attgagtcccttttcgatcacatctatactactcaaagtgatgtgtggtcctttggagtg
ctgctctgggagattgtgaccctgggaggcaacccctaccctggaattcctcctgaacga
ctcttcaaccttctgaagacaggccacaggatggagaggccagacaactgcagcgaggaa
atgtaccgtctgatgctgcagtgctggaagcaggagccagacaagaggccagtgtttgct
gacatcagcaaggatctggagaagatgatggtcaagagcagagactacttggacctggct
gcatccacaccttcggactcactgctgtatgacgatgggctctcagaagaggagacaccc
ctggtggactgtaacaatgctcccctcccgcgctccctcccttccacatggattgaaaac
aaactctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacgaga
gccgatggcactagcactgggttcccaagatatgcaaatgatagtgtatatgctaactgg
atggtttcaccctcagcggcaaaattaatggacacatttgatagctaa |
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