| Entry |
|
|---|
| Symbol |
Ikbke, IKK-E, IKK-i, IKKepsilon, Ikki
|
|---|
| Name |
(RefSeq) inhibitor of kappaB kinase epsilon
|
|---|
| KO |
| K07211 | inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] |
|
|---|
| Organism |
mmu Mus musculus (house mouse)
|
|---|
| Pathway |
| mmu04620 | Toll-like receptor signaling pathway |
| mmu04621 | NOD-like receptor signaling pathway |
| mmu04622 | RIG-I-like receptor signaling pathway |
| mmu04625 | C-type lectin receptor signaling pathway |
| mmu05167 | Kaposi sarcoma-associated herpesvirus infection |
| mmu05168 | Herpes simplex virus 1 infection |
| mmu05207 | Chemical carcinogenesis - receptor activation |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
56489 (Ikbke)
04657 IL-17 signaling pathway
56489 (Ikbke)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
56489 (Ikbke)
09172 Infectious disease: viral
05161 Hepatitis B
56489 (Ikbke)
05160 Hepatitis C
56489 (Ikbke)
05171 Coronavirus disease - COVID-19
56489 (Ikbke)
05164 Influenza A
56489 (Ikbke)
05162 Measles
56489 (Ikbke)
05167 Kaposi sarcoma-associated herpesvirus infection
56489 (Ikbke)
05169 Epstein-Barr virus infection
56489 (Ikbke)
05165 Human papillomavirus infection
56489 (Ikbke)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
56489 (Ikbke)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
56489 (Ikbke)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mmu01001]
56489 (Ikbke)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
56489 (Ikbke)
Protein kinases [BR:mmu01001]
Serine/threonine kinases: Other
IKK family [OT]
56489 (Ikbke)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
1:complement(131182337..131207339)
|
|---|
| AA seq |
717 aa
MQSTTNYLWHTDDLLGQGATASVYKARNKKSGEVVAVKVFNSASYRRPPEVQVREFEVLR
RLNHQNIVKLFAVEETGGSRQKVLIMEYCSSGSLLSVLEDPENTFGLSEEEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE
KPAGAISGTQKQENGPLEWSYSLPITCRLSMGLQNQLVPILANILEVEEDKCWGFDQFFA
ETSDILQRTVIHVFSLPQAVLHHVYIHAHNTIAIFLEAVYEQTNVTPKHQEYLFEGHPCV
LEPSLSAQHIAHTAASSPLTLFSMSSDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGV
LGAGYQALWLARVLLDGQALMLRGLHWVLEVLQDTCQQTLEVTRTALLYLSSSLGTERFS
SGAGMPDVQERKEATELRTRLQTLSEILSKCSHNVTETQRSLSCLGEELLKNRDQIHEDN
KSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECV
QTYQVSLVTHGKRMRQVQRAQNHLHLIGHSVATCNSEARGAQESLNKIFDQLLLDRASEQ
GAEVSPQPMAPHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPSAPDV |
|---|
| NT seq |
2154 nt +upstreamnt +downstreamnt
atgcagagtaccactaactacctgtggcatactgatgacctgctagggcagggggccact
gccagtgtgtacaaggcccgaaacaagaaatccggggaggtggttgctgtaaaggtcttc
aactcagccagctatcggcgacctcctgaggttcaggtgagggagtttgaggtcctgcgg
aggctgaatcaccagaacatcgtgaagctattcgcagtggaggaaacgggaggcagccgg
cagaaggtgctaatcatggagtactgctccagtgggagcctgctgagcgtgctggaagac
cctgagaacacgttcgggctttctgaagaggagttcctagtggtgctgcgctgtgtggtg
gctggcatgaaccacctgcgggagaatggcattgtccatcgggacatcaaacctgggaac
atcatgcgcctggtgggcgaggaggggcagagcatctataagctgtctgacttcggggct
gcccgcaagctggacgatgatgagaagtttgtttctgtctatggtacagaggaatacctg
caccctgacatgtatgagcgtgcagtgctgcgcaaaccccagcaaaaggcatttggtgtg
actgtggatctctggagtattggggtgaccctgtaccacgcagccacaggcagtctgccc
ttcatccccttcggtgggccccggcgcaacaaagagatcatgtacagaatcaccacagag
aagccagccggggccatttcagggactcagaagcaggaaaatggtcccttggagtggagc
tacagcctccccatcacctgtagactgtccatgggactgcagaaccagctggtgcccatc
ctggccaacatcctggaggtggaagaggataagtgctggggctttgatcagttcttcgcg
gagaccagtgacattctgcagcgaacggtcatccacgtcttttccctaccccaggccgtt
ttgcatcatgtctacatccacgcccacaacacgattgccatctttttggaggctgtatat
gagcagaccaacgtgacccccaaacaccaggagtacctcttcgagggtcacccttgtgtc
cttgagccaagcctctcagcccagcacatcgcccacacagctgccagcagccctctaact
ctgttcagcatgtccagcgacacacctaaggggctggccttcagggaccctgctctggat
gtcccaaagttcgtccctaaggttgacctacaggccgattacagcacagctaagggggtg
ctgggcgctggctaccaggccctgtggctggcgcgggtcctgctggatggacaggcgttg
atgcttcgggggttacattgggtcctggaggtgcttcaggacacgtgccagcagacactg
gaggtcacacggacagccctcctctacctcagcagcagcctgggcactgaaaggttcagc
agtggagcggggatgcctgacgtccaggaacgaaaggaggccacagagctaagaaccagg
ctgcagactctctcagagatcctgtctaaatgttcccacaatgtcacagaaacccaaagg
agcctgagctgtctgggtgaagagcttttaaagaaccgggaccagattcatgaggataac
aaaagtatccagaagattcagtgttgtttggacaagatgcacttcatctacaaacagttc
aagaaatccaggatgaggccagggctcagctacaatgaggagcagatccacaagctggat
aaggtaaatttcagtcatctagccaagaggctgctgcaggtgttccaggaggagtgtgtg
cagacgtatcaggtgtcgctggtcacacacggcaagcggatgaggcaggtgcagagggcc
cagaaccacctgcatctcattggccactctgtggccacctgtaactcggaagcccgggga
gcccaggagagtctgaacaagatctttgatcagctccttctggacagagcttccgaacag
ggagctgaggtgtcaccgcaacctatggctcctcatcccggccctgatccgaaggacctg
gtcttccacatgcaggagctttgtaatgatatgaagctattggcctttgatctccaggac
aacaaccgactcatcgaacggttacatagagttccatcggcaccagatgtctga |
|---|
