| Entry |
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| Symbol |
MET
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| Name |
(RefSeq) hepatocyte growth factor receptor precursor
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| KO |
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| Organism |
oaa Ornithorhynchus anatinus (platypus)
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| Pathway |
| oaa01521 | EGFR tyrosine kinase inhibitor resistance |
| oaa05100 | Bacterial invasion of epithelial cells |
| oaa05202 | Transcriptional misregulation in cancer |
| oaa05208 | Chemical carcinogenesis - reactive oxygen species |
| oaa05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:oaa00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100079345 (MET)
04015 Rap1 signaling pathway
100079345 (MET)
04151 PI3K-Akt signaling pathway
100079345 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
100079345 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100079345 (MET)
05202 Transcriptional misregulation in cancer
100079345 (MET)
05206 MicroRNAs in cancer
100079345 (MET)
05205 Proteoglycans in cancer
100079345 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
100079345 (MET)
05230 Central carbon metabolism in cancer
100079345 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100079345 (MET)
05226 Gastric cancer
100079345 (MET)
05218 Melanoma
100079345 (MET)
05211 Renal cell carcinoma
100079345 (MET)
05223 Non-small cell lung cancer
100079345 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
100079345 (MET)
09174 Infectious disease: parasitic
05144 Malaria
100079345 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100079345 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:oaa01001]
100079345 (MET)
Enzymes [BR:oaa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100079345 (MET)
Protein kinases [BR:oaa01001]
Receptor tyrosine kinases (RTK)
MET family
100079345 (MET)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
10:39283809..39403668
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| AA seq |
1382 aa
MKPPTVHIPGIVVLLFTLVQRSSEECREALRRSGTDVNVSYSLPHFIANTTLLNIVVHRD
DLYLGAVNKIYVLDKNLQDFVEYPTGPVLEHPDCAPCENCSAIAHSSKADLRDNVNMALL
IETYYHYEQLIICGSVDGGACWRFPLPLGEPTDFHSKKHCMFSHQADEESKDCPDCIVST
LGTKVLLVEKDRFVNFFVGNTINSSSHPFSSLHSISVRRLKETLDGFKFLTDQSYIDVLP
QFRDSYPIKYIHAFESNQFIYFLTVQKETVESQTFHTRIIRFCSMDSELHSYMEMPLECI
LTEKRRRRSTNKEVFNVLQAAYVSKPGAHLARQIGTGLNDDILYGVFAQSKPDSAEPMNR
SAICAFPIKYINEFFSKIVNKNNVRCLQHFYGNHHRHCANRTFQWNSSGCEVRDDEYRME
FTTPLQRVDLSMGKFSHVLLTSISTFIKGNLTVANLGTAEGRFMQVVISRSDPPSPHVDF
LLDNHPVSPEVIVVNSSMPDGYTLVITGKKITKIPLNGLGCDHFKSCRQCLSAPSFVQCG
WCDDRCTTAEKCDYGLWTQDTCPPTIFEIIPSSAPLEGGTMLTVCGWDFGFQKNNKFELR
KTKVLVGNQSCTLFFNESSTNKLKCTAGPSTQPRLNISISVSNAQGGRRSKTFSYVDPKI
TSISPRYGPIAGGTLLTLTGKYLNCGSSRHISIGGKTCTLRSVSEHVLECYTPSQTVPTL
YAVKMKIDLANREAGTFIYKEDPVIHEIHPTKSFLSGGSTITGFGKNLNGSSAPKMIIQV
AEVGRNFTVACQSRSNAEIICCTTPSLQQLNLPPPFKTKAFFVFDGVQSANFDLIYVHNP
VFKLFEKPVMISMGNKHVLEIKGDHIDSEAVKGEVLKVGNKSCENVLLNLESVFCTVPRD
LLKVNTELNIEWQQAVSSTILGKVIVLPDQNFTGLIAGVASISVLLLLFLGLFLWMKKKK
QIKDLGSELVRYDPRVHTPHLDRLVSARSISPTAEMVSNESVDYRATFPEDQFPNSSQNG
SCRQAHYPLADLSPILSSGDSNPSSPLLQSNVHIDISALNPDLVQAVQHVVIGPDSLMVH
FTEIIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV
LSLLGICLRREGSPLVVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTSKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLFEVMLKC
WHPNAEMRPSFSELVSKIAVIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDAPDRVV
DT |
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| NT seq |
4149 nt +upstreamnt +downstreamnt
atgaagccccccactgttcacattcccggaattgtggtgctcctgttcactttggtccag
aggagcagcgaagagtgcagagaagccctgaggaggtctgggacagatgtcaacgtgagc
tactcgctgccccacttcatcgcgaataccaccctcctaaatatcgtcgtccaccgggat
gacctctatctgggcgccgtcaacaagatctacgtcttagacaaaaacctccaggacttc
gtagagtacccgactgggccagtgttggaacatcctgactgcgctccatgtgagaactgc
tccgccatagcccattcgtcgaaagcagacttgagggataacgtcaacatggccctgctg
atcgagacctactaccactatgagcaactgatcatctgcgggagtgtggatggaggggcc
tgctggaggttccccctgcctcttggggagccgactgacttccactccaaaaagcactgc
atgttctcccaccaggccgacgaagagtccaaagactgccccgactgcatcgtgagcacg
ctgggaaccaaagtcctgctggtcgagaaagaccgatttgtcaacttctttgtgggcaat
accatcaactcgtcttctcaccctttctcgtctctgcattccatctccgtgaggcggctg
aaggaaactctggatggctttaagttcttgacggatcagtcttacatcgacgttctgccg
cagttccgagattcgtaccccatcaagtacatccacgcttttgagagtaatcagttcatc
tatttcctgaccgtacagaaagaaactgtggaatcccaaactttccacacaagaattatc
cggttctgttcaatggattcggaattacattcctacatggaaatgcctctcgaatgcatc
ctcacagagaagaggaggaggaggtccaccaacaaggaagtgttcaatgtcctccaggct
gcctatgtcagtaagccaggggcccatctggctcggcaaataggaaccggattaaatgat
gacattctctatggggtgtttgcgcagagtaagccagactccgcagaacccatgaaccga
tctgctatctgcgcattccccatcaaatacatcaatgagttcttcagcaagattgtcaac
aagaacaacgtgaggtgtctgcaacacttttatgggaaccaccacagacactgtgcgaat
aggactttccagtggaattcttcgggctgcgaggtgcgtgatgacgaataccgcatggag
ttcaccacccctttacagcgcgtcgacctgtccatggggaagttcagtcatgtcctcctg
acgtcgatatccaccttcatcaaagggaacctcaccgtggccaatcttggcaccgccgag
gggcgattcatgcaggttgtgatttctcgctcagatccaccttcccctcatgtggatttt
cttctggacaaccacccggtctcccccgaagtcatcgtggtcaattcttcaatgccagat
ggctacacgctggtcatcacgggcaagaagataacgaagatcccactgaatggccttggc
tgtgatcacttcaagtcctgcaggcagtgtctgtcggctccctctttcgtgcagtgcggt
tggtgtgacgaccggtgcactactgcagagaagtgcgattatgggctgtggacccaagac
acctgcccacccacaatttttgagataatccccagcagtgcacccctggaaggaggaacc
atgctgactgtgtgtggctgggacttcggattccaaaagaataacaagtttgagctgagg
aaaaccaaggttctcgtcggcaaccagagctgcactctgttcttcaacgagagctccaca
aacaagctgaaatgcactgccgggccttccacccagccccgcctcaacatctccatcagt
gtttccaatgcccaaggcggaagacgatccaaaacgttctcgtacgtggaccctaagata
accagtatttctccccgctatggtcccatagctggaggaactttactcaccttaactggg
aagtacctgaactgtggaagttccagacacatttccatcggcggaaaaacatgcaccttg
aggagtgtgtcggaacacgttctagaatgctacacgccttcccagaccgtacccaccctc
tatgcggttaagatgaagatcgacttggccaatcgcgaagccggcactttcatctacaag
gaggaccccgtcatccatgagattcacccaaccaaatcattccttagtggcggaagcaca
atcaccggatttgggaaaaacctcaacggatccagtgctcctaagatgatcatccaagtc
gcagaagtgggcaggaacttcacagtagcatgtcaaagtcgttctaatgcagaaataatc
tgttgtacgactccttcactgcagcaactaaatctgccaccccccttcaaaacgaaagca
ttttttgtatttgatggggtccagtctgctaactttgacctcatttatgtgcacaatcca
gtgtttaagctgtttgaaaagccagtgatgatctcaatgggcaacaaacatgtactggaa
attaagggagaccatattgattccgaagcagtcaaaggggaggtgctgaaagttggaaat
aaaagctgcgagaacgtcctcttgaacttggaatctgtattctgcacggtccccagggat
ctgctgaaagtgaatacggagttaaatatagagtggcagcaggcagtctcctcgaccatc
cttggaaaggtgattgttctccctgaccagaatttcacaggactaatcgccggagtggcc
tccatctcggtcttactcttgttattcctgggcctttttctgtggatgaaaaagaagaaa
caaattaaagatctgggcagtgaattagttcgctatgacccaagagttcacacgcctcac
ctggaccgccttgtaagcgccaggagtatcagccccacggcggaaatggtttccaatgaa
tctgtggactaccgagcgacgttcccagaagatcagtttcccaattcctctcagaacgga
tcatgcagacaagcccattatcccctggccgacctgtcgcccattctctccagtggggac
tccaacccatctagcccacttctacagagcaacgttcacattgacatcagcgccctgaac
ccagatctagtccaagccgttcagcacgtggtgatcggaccagacagcctgatggtgcat
ttcactgaaatcataggaagaggtcattttgggtgtgtgtatcacggaactctgttggat
aatgatgacaaaaaaatccactgtgctgtgaagtccttgaatagaatcactgacatcgag
gaggtgtcacagttcctcaccgaggggatcatcatgaaggatttcagccaccccaacgtc
ctctcgctgctggggatctgtctccgcagggaagggtcacccctggtggtcttaccctac
atgaagcatggagacctacgcaactttataaggaacgaatctcacaatcccaccgtgaaa
gacctcatcggatttggcctccaagtggccaaaggtatgaaataccttgccagcaaaaag
tttgtccaccgagacttggctgcccgaaattgtatgctggatgaaaaattcactgtcaag
gtggctgattttggcctggcccgagatatgtacgataaagaatattacagcgtgcacaat
aaaacgggagccaagctgccagtgaaatggatggctctcgaaagtctgcagacacagaag
ttcacctccaagtcagatgtgtggtccttcggcgtccttctctgggagctgatgacacga
ggcgctcccccgtatcccgacgtgaacactttcgatataacggtctacctgctgcaagga
aggaggctgctacagccagaatactgtccggacccactatttgaagtcatgctaaaatgc
tggcatcccaacgctgaaatgcgcccgtccttctcggaactggtttcaaagatagcggtc
atcttctccactttcatcggcgagcattacgtccacgtgaacgccacctacgtcaacgtc
aagtgcgtggcgccctacccatccctcctgtcctcgcaggacgccccagacagggttgtg
gacacatga |
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