| Entry |
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| Symbol |
LYS2
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| Name |
(RefSeq) L-aminoadipate-semialdehyde dehydrogenase
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| KO |
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| Organism |
sce Saccharomyces cerevisiae (budding yeast)
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| Pathway |
| sce01110 | Biosynthesis of secondary metabolites |
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| Module |
| sce_M00030 | Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine |
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| Brite |
KEGG Orthology (KO) [BR:sce00001]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
YBR115C (LYS2)
Enzymes [BR:sce01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.95 L-2-aminoadipate reductase
YBR115C (LYS2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
II:complement(469748..473926)
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| AA seq |
1392 aa
MTNEKVWIEKLDNPTLSVLPHDFLRPQQEPYTKQATYSLQLPQLDVPHDSFSNKYAVALS
VWAALIYRVTGDDDIVLYIANNKILRFNIQPTWSFNELYSTINNELNKLNSIEANFSFDE
LAEKIQSCQDLERTPQLFRLAFLENQDFKLDEFKHHLVDFALNLDTSNNAHVLNLIYNSL
LYSNERVTIVADQFTQYLTAALSDPSNCITKISLITASSKDSLPDPTKNLGWCDFVGCIH
DIFQDNAEAFPERTCVVETPTLNSDKSRSFTYRDINRTSNIVAHYLIKTGIKRGDVVMIY
SSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPRGLIVIRAAGQLDQLVED
YINDELEIVSRINSIAIQENGTIEGGKLDNGEDVLAPYDHYKDTRTGVVVGPDSNPTLSF
TSGSEGIPKGVLGRHFSLAYYFNWMSKRFNLTENDKFTMLSGIAHDPIQRDMFTPLFLGA
QLYVPTQDDIGTPGRLAEWMSKYGCTVTHLTPAMGQLLTAQATTPFPKLHHAFFVGDILT
KRDCLRLQTLAENCRIVNMYGTTETQRAVSYFEVKSKNDDPNFLKKLKDVMPAGKGMLNV
QLLVVNRNDRTQICGIGEIGEIYVRAGGLAEGYRGLPELNKEKFVNNWFVEKDHWNYLDK
DNGEPWRQFWLGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTHISQ
HPLVRENITLVRKNADNEPTLITFMVPRFDKPDDLSKFQSDVPKEVETDPIVKGLIGYHL
LSKDIRTFLKKRLASYAMPSLIVVMDKLPLNPNGKVDKPKLQFPTPKQLNLVAENTVSET
DDSQFTNVEREVRDLWLSILPTKPASVSPDDSFFDLGGHSILATKMIFTLKKKLQVDLPL
GTIFKYPTIKAFAAEIDRIKSSGGSSQGEVVENVTANYAEDAKKLVETLPSSYPSREYFV
EPNSAEGKTTINVFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQK
AGITYGTWNEKFASNIKVVLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAK
LRDPNVISTINVMSLAAVGKPKFFDFVSSTSTLDTEYYFNLSDKLVSEGKPGILESDDLM
NSASGLTGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASANGSSNTDDFLLRFLKG
SVQLGKIPDIENSVNMVPVDHVARVVVATSLNPPKENELAVAQVTGHPRILFKDYLYTLH
DYGYDVEIESYSKWKKSLEASVIDRNEENALYPLLHMVLDNLPESTKAPELDDRNAVASL
KKDTAWTGVDWSNGIGVTPEEVGIYIAFLNKVGFLPPPTHNDKLPLPSIELTQAQISLVA
SGAGARGSSAAA |
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| NT seq |
4179 nt +upstreamnt +downstreamnt
atgactaacgaaaaggtctggatagagaagttggataatccaactctttcagtgttacca
catgactttttacgcccacaacaagaaccttatacgaaacaagctacatattcgttacag
ctacctcagctcgatgtgcctcatgatagtttttctaacaaatacgctgtcgctttgagt
gtatgggctgcattgatatatagagtaaccggtgacgatgatattgttctttatattgcg
aataacaaaatcttaagattcaatattcaaccaacgtggtcatttaatgagctgtattct
acaattaacaatgagttgaacaagctcaattctattgaggccaatttttcctttgacgag
ctagctgaaaaaattcaaagttgccaagatctggaaaggacccctcagttgttccgtttg
gcctttttggaaaaccaagatttcaaattagacgagttcaagcatcatttagtggacttt
gctttgaatttggataccagtaataatgcgcatgttttgaacttaatttataacagctta
ctgtattcgaatgaaagagtaaccattgttgcggaccaatttactcaatatttgactgct
gcgctaagcgatccatccaattgcataactaaaatctctctgatcaccgcatcatccaag
gatagtttacctgatccaactaagaacttgggctggtgcgatttcgtggggtgtattcac
gacattttccaggacaatgctgaagccttcccagagagaacctgtgttgtggagactcca
acactaaattccgacaagtcccgttctttcacttatcgcgacatcaaccgcacttctaac
atagttgcccattatttgattaaaacaggtatcaaaagaggtgatgtagtgatgatctat
tcttctaggggtgtggatttgatggtatgtgtgatgggtgtcttgaaagccggcgcaacc
ttttcagttatcgaccctgcatatcccccagccagacaaaccatttacttaggtgttgct
aaaccacgtgggttgattgttattagagctgctggacaattggatcaactagtagaagat
tacatcaatgatgaattggagattgtttcaagaatcaattccatcgctattcaagaaaat
ggtaccattgaaggtggcaaattggacaatggcgaggatgttttggctccatatgatcac
tacaaagacaccagaacaggtgttgtagttggaccagattccaacccaaccctatctttc
acatctggttccgaaggtattcctaagggtgttcttggtagacatttttccttggcttat
tatttcaattggatgtccaaaaggttcaacttaacagaaaatgataaattcacaatgctg
agcggtattgcacatgatccaattcaaagagatatgtttacaccattatttttaggtgcc
caattgtatgtccctactcaagatgatattggtacaccgggccgtttagcggaatggatg
agtaagtatggttgcacagttacccatttaacacctgccatgggtcaattacttactgcc
caagctactacaccattccctaagttacatcatgcgttctttgtgggtgacattttaaca
aaacgtgattgtctgaggttacaaaccttggcagaaaattgccgtattgttaatatgtac
ggtaccactgaaacacagcgtgcagtttcttatttcgaagttaaatcaaaaaatgacgat
ccaaactttttgaaaaaattgaaagatgtcatgcctgctggtaaaggtatgttgaacgtt
cagctactagttgttaacaggaacgatcgtactcaaatatgtggtattggcgaaataggt
gagatttatgttcgtgcaggtggtttggccgaaggttatagaggattaccagaattgaat
aaagaaaaatttgtgaacaactggtttgttgaaaaagatcactggaattatttggataag
gataatggtgaaccttggagacaattctggttaggtccaagagatagattgtacagaacg
ggtgatttaggtcgttatctaccaaacggtgactgtgaatgttgcggtagggctgatgat
caagttaaaattcgtgggttcagaatcgaattaggagaaatagatacgcacatttcccaa
catccattggtaagagaaaacattactttagttcgcaaaaatgccgacaatgagccaaca
ttgatcacatttatggtcccaagatttgacaagccagatgacttgtctaagttccaaagt
gatgttccaaaggaggttgaaactgaccctatagttaagggcttaatcggttaccatctt
ttatccaaggacatcaggactttcttaaagaaaagattggctagctatgctatgccttcc
ttgattgtggttatggataaactaccattgaatccaaatggtaaagttgataagcctaaa
cttcaattcccaactcccaagcaattaaatttggtagctgaaaatacagtttctgaaact
gacgactctcagtttaccaatgttgagcgcgaggttagagacttatggttaagtatatta
cctaccaagccagcatctgtatcaccagatgattcgtttttcgatttaggtggtcattct
atcttggctaccaaaatgatttttaccttaaagaaaaagctgcaagttgatttaccattg
ggcacaattttcaagtatccaacgataaaggcctttgccgcggaaattgacagaattaaa
tcatcgggtggatcatctcaaggtgaggtcgtcgaaaatgtcactgcaaattatgcggaa
gacgccaagaaattggttgagacgctaccaagttcgtacccctctcgagaatattttgtt
gaacctaatagtgccgaaggaaaaacaacaattaatgtgtttgttaccggtgtcacagga
tttctgggctcctacatccttgcagatttgttaggacgttctccaaagaactacagtttc
aaagtgtttgcccacgtcagggccaaggatgaagaagctgcatttgcaagattacaaaag
gcaggtatcacctatggtacttggaacgaaaaatttgcctcaaatattaaagttgtatta
ggcgatttatctaaaagccaatttggtctttcagatgagaagtggatggatttggcaaac
acagttgatataattatccataatggtgcgttagttcactgggtttatccatatgccaaa
ttgagggatccaaatgttatttcaactatcaatgttatgagcttagccgccgtcggcaag
ccaaagttctttgactttgtttcctccacttctactcttgacactgaatactactttaat
ttgtcagataaacttgttagcgaagggaagccaggcattttagaatcagacgatttaatg
aactctgcaagcgggctcactggtggatatggtcagtccaaatgggctgctgagtacatc
attagacgtgcaggtgaaaggggcctacgtgggtgtattgtcagaccaggttacgtaaca
ggtgcctctgccaatggttcttcaaacacagatgatttcttattgagatttttgaaaggt
tcagtccaattaggtaagattccagatatcgaaaattccgtgaatatggttccagtagat
catgttgctcgtgttgttgttgctacgtctttgaatcctcccaaagaaaatgaattggcc
gttgctcaagtaacgggtcacccaagaatattattcaaagactacttgtatactttacac
gattatggttacgatgtcgaaatcgaaagctattctaaatggaagaaatcattggaggcg
tctgttattgacaggaatgaagaaaatgcgttgtatcctttgctacacatggtcttagac
aacttacctgaaagtaccaaagctccggaactagacgataggaacgccgtggcatcttta
aagaaagacaccgcatggacaggtgttgattggtctaatggaataggtgttactccagaa
gaggttggtatatatattgcatttttaaacaaggttggatttttacctccaccaactcat
aatgacaaacttccactgccaagtatagaactaactcaagcgcaaataagtctagttgct
tcaggtgctggtgctcgtggaagctccgcagcagcttaa |
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