Saccharomyces cerevisiae (budding yeast): YBR115C
Help
Entry
YBR115C CDS
T00005
Symbol
LYS2
Name
(RefSeq) L-aminoadipate-semialdehyde dehydrogenase
KO
K00143
L-2-aminoadipate reductase [EC:
1.2.1.95
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00300
Lysine biosynthesis
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01230
Biosynthesis of amino acids
Module
sce_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
YBR115C (LYS2)
Enzymes [BR:
sce01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.95 L-2-aminoadipate reductase
YBR115C (LYS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NAD_binding_4
AMP-binding
PP-binding
Epimerase
Condensation
3Beta_HSD
AMP-binding_C
GDP_Man_Dehyd
Choline_bind_3
Motif
Other DBs
NCBI-GeneID:
852412
NCBI-ProteinID:
NP_009673
SGD:
S000000319
UniProt:
P07702
LinkDB
All DBs
Position
II:complement(469748..473926)
Genome browser
AA seq
1392 aa
AA seq
DB search
MTNEKVWIEKLDNPTLSVLPHDFLRPQQEPYTKQATYSLQLPQLDVPHDSFSNKYAVALS
VWAALIYRVTGDDDIVLYIANNKILRFNIQPTWSFNELYSTINNELNKLNSIEANFSFDE
LAEKIQSCQDLERTPQLFRLAFLENQDFKLDEFKHHLVDFALNLDTSNNAHVLNLIYNSL
LYSNERVTIVADQFTQYLTAALSDPSNCITKISLITASSKDSLPDPTKNLGWCDFVGCIH
DIFQDNAEAFPERTCVVETPTLNSDKSRSFTYRDINRTSNIVAHYLIKTGIKRGDVVMIY
SSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPRGLIVIRAAGQLDQLVED
YINDELEIVSRINSIAIQENGTIEGGKLDNGEDVLAPYDHYKDTRTGVVVGPDSNPTLSF
TSGSEGIPKGVLGRHFSLAYYFNWMSKRFNLTENDKFTMLSGIAHDPIQRDMFTPLFLGA
QLYVPTQDDIGTPGRLAEWMSKYGCTVTHLTPAMGQLLTAQATTPFPKLHHAFFVGDILT
KRDCLRLQTLAENCRIVNMYGTTETQRAVSYFEVKSKNDDPNFLKKLKDVMPAGKGMLNV
QLLVVNRNDRTQICGIGEIGEIYVRAGGLAEGYRGLPELNKEKFVNNWFVEKDHWNYLDK
DNGEPWRQFWLGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTHISQ
HPLVRENITLVRKNADNEPTLITFMVPRFDKPDDLSKFQSDVPKEVETDPIVKGLIGYHL
LSKDIRTFLKKRLASYAMPSLIVVMDKLPLNPNGKVDKPKLQFPTPKQLNLVAENTVSET
DDSQFTNVEREVRDLWLSILPTKPASVSPDDSFFDLGGHSILATKMIFTLKKKLQVDLPL
GTIFKYPTIKAFAAEIDRIKSSGGSSQGEVVENVTANYAEDAKKLVETLPSSYPSREYFV
EPNSAEGKTTINVFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQK
AGITYGTWNEKFASNIKVVLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAK
LRDPNVISTINVMSLAAVGKPKFFDFVSSTSTLDTEYYFNLSDKLVSEGKPGILESDDLM
NSASGLTGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASANGSSNTDDFLLRFLKG
SVQLGKIPDIENSVNMVPVDHVARVVVATSLNPPKENELAVAQVTGHPRILFKDYLYTLH
DYGYDVEIESYSKWKKSLEASVIDRNEENALYPLLHMVLDNLPESTKAPELDDRNAVASL
KKDTAWTGVDWSNGIGVTPEEVGIYIAFLNKVGFLPPPTHNDKLPLPSIELTQAQISLVA
SGAGARGSSAAA
NT seq
4179 nt
NT seq
+upstream
nt +downstream
nt
atgactaacgaaaaggtctggatagagaagttggataatccaactctttcagtgttacca
catgactttttacgcccacaacaagaaccttatacgaaacaagctacatattcgttacag
ctacctcagctcgatgtgcctcatgatagtttttctaacaaatacgctgtcgctttgagt
gtatgggctgcattgatatatagagtaaccggtgacgatgatattgttctttatattgcg
aataacaaaatcttaagattcaatattcaaccaacgtggtcatttaatgagctgtattct
acaattaacaatgagttgaacaagctcaattctattgaggccaatttttcctttgacgag
ctagctgaaaaaattcaaagttgccaagatctggaaaggacccctcagttgttccgtttg
gcctttttggaaaaccaagatttcaaattagacgagttcaagcatcatttagtggacttt
gctttgaatttggataccagtaataatgcgcatgttttgaacttaatttataacagctta
ctgtattcgaatgaaagagtaaccattgttgcggaccaatttactcaatatttgactgct
gcgctaagcgatccatccaattgcataactaaaatctctctgatcaccgcatcatccaag
gatagtttacctgatccaactaagaacttgggctggtgcgatttcgtggggtgtattcac
gacattttccaggacaatgctgaagccttcccagagagaacctgtgttgtggagactcca
acactaaattccgacaagtcccgttctttcacttatcgcgacatcaaccgcacttctaac
atagttgcccattatttgattaaaacaggtatcaaaagaggtgatgtagtgatgatctat
tcttctaggggtgtggatttgatggtatgtgtgatgggtgtcttgaaagccggcgcaacc
ttttcagttatcgaccctgcatatcccccagccagacaaaccatttacttaggtgttgct
aaaccacgtgggttgattgttattagagctgctggacaattggatcaactagtagaagat
tacatcaatgatgaattggagattgtttcaagaatcaattccatcgctattcaagaaaat
ggtaccattgaaggtggcaaattggacaatggcgaggatgttttggctccatatgatcac
tacaaagacaccagaacaggtgttgtagttggaccagattccaacccaaccctatctttc
acatctggttccgaaggtattcctaagggtgttcttggtagacatttttccttggcttat
tatttcaattggatgtccaaaaggttcaacttaacagaaaatgataaattcacaatgctg
agcggtattgcacatgatccaattcaaagagatatgtttacaccattatttttaggtgcc
caattgtatgtccctactcaagatgatattggtacaccgggccgtttagcggaatggatg
agtaagtatggttgcacagttacccatttaacacctgccatgggtcaattacttactgcc
caagctactacaccattccctaagttacatcatgcgttctttgtgggtgacattttaaca
aaacgtgattgtctgaggttacaaaccttggcagaaaattgccgtattgttaatatgtac
ggtaccactgaaacacagcgtgcagtttcttatttcgaagttaaatcaaaaaatgacgat
ccaaactttttgaaaaaattgaaagatgtcatgcctgctggtaaaggtatgttgaacgtt
cagctactagttgttaacaggaacgatcgtactcaaatatgtggtattggcgaaataggt
gagatttatgttcgtgcaggtggtttggccgaaggttatagaggattaccagaattgaat
aaagaaaaatttgtgaacaactggtttgttgaaaaagatcactggaattatttggataag
gataatggtgaaccttggagacaattctggttaggtccaagagatagattgtacagaacg
ggtgatttaggtcgttatctaccaaacggtgactgtgaatgttgcggtagggctgatgat
caagttaaaattcgtgggttcagaatcgaattaggagaaatagatacgcacatttcccaa
catccattggtaagagaaaacattactttagttcgcaaaaatgccgacaatgagccaaca
ttgatcacatttatggtcccaagatttgacaagccagatgacttgtctaagttccaaagt
gatgttccaaaggaggttgaaactgaccctatagttaagggcttaatcggttaccatctt
ttatccaaggacatcaggactttcttaaagaaaagattggctagctatgctatgccttcc
ttgattgtggttatggataaactaccattgaatccaaatggtaaagttgataagcctaaa
cttcaattcccaactcccaagcaattaaatttggtagctgaaaatacagtttctgaaact
gacgactctcagtttaccaatgttgagcgcgaggttagagacttatggttaagtatatta
cctaccaagccagcatctgtatcaccagatgattcgtttttcgatttaggtggtcattct
atcttggctaccaaaatgatttttaccttaaagaaaaagctgcaagttgatttaccattg
ggcacaattttcaagtatccaacgataaaggcctttgccgcggaaattgacagaattaaa
tcatcgggtggatcatctcaaggtgaggtcgtcgaaaatgtcactgcaaattatgcggaa
gacgccaagaaattggttgagacgctaccaagttcgtacccctctcgagaatattttgtt
gaacctaatagtgccgaaggaaaaacaacaattaatgtgtttgttaccggtgtcacagga
tttctgggctcctacatccttgcagatttgttaggacgttctccaaagaactacagtttc
aaagtgtttgcccacgtcagggccaaggatgaagaagctgcatttgcaagattacaaaag
gcaggtatcacctatggtacttggaacgaaaaatttgcctcaaatattaaagttgtatta
ggcgatttatctaaaagccaatttggtctttcagatgagaagtggatggatttggcaaac
acagttgatataattatccataatggtgcgttagttcactgggtttatccatatgccaaa
ttgagggatccaaatgttatttcaactatcaatgttatgagcttagccgccgtcggcaag
ccaaagttctttgactttgtttcctccacttctactcttgacactgaatactactttaat
ttgtcagataaacttgttagcgaagggaagccaggcattttagaatcagacgatttaatg
aactctgcaagcgggctcactggtggatatggtcagtccaaatgggctgctgagtacatc
attagacgtgcaggtgaaaggggcctacgtgggtgtattgtcagaccaggttacgtaaca
ggtgcctctgccaatggttcttcaaacacagatgatttcttattgagatttttgaaaggt
tcagtccaattaggtaagattccagatatcgaaaattccgtgaatatggttccagtagat
catgttgctcgtgttgttgttgctacgtctttgaatcctcccaaagaaaatgaattggcc
gttgctcaagtaacgggtcacccaagaatattattcaaagactacttgtatactttacac
gattatggttacgatgtcgaaatcgaaagctattctaaatggaagaaatcattggaggcg
tctgttattgacaggaatgaagaaaatgcgttgtatcctttgctacacatggtcttagac
aacttacctgaaagtaccaaagctccggaactagacgataggaacgccgtggcatcttta
aagaaagacaccgcatggacaggtgttgattggtctaatggaataggtgttactccagaa
gaggttggtatatatattgcatttttaaacaaggttggatttttacctccaccaactcat
aatgacaaacttccactgccaagtatagaactaactcaagcgcaaataagtctagttgct
tcaggtgctggtgctcgtggaagctccgcagcagcttaa
DBGET
integrated database retrieval system
